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Metabolic activation and deactivation of arylamine carcinogens by recombinant human NAT1 and polymorphic NAT2 acetyltransferases

Carcinogenesis (New York), 1993-08, Vol.14 (8), p.1633-1638

1993

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Metabolic activation of N-hydroxyarylamines and N-hydroxyarylamides by 16 recombinant human NAT2 allozymes: effects of 7 specific NAT2 nucleic acid substitutions

Cancer research (Chicago, Ill.), 1995-08, Vol.55 (16), p.3531-3536

1995

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Molecular genetics of human polymorphic N-acetyltransferase: enzymatic analysis of 15 recombinant wild-type, mutant, and chimeric NAT2 allozymes

Human molecular genetics, 1994-05, Vol.3 (5), p.729-734

1994

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Human N-acetylation of benzidine : Role of NAT1 and NAT2

Cancer research (Chicago, Ill.), 1996-09, Vol.56 (17), p.3941-3947

1996

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Prostate-specific human N-acetyltransferase 2 (NAT2) expression in the mouse

The Journal of pharmacology and experimental therapeutics, 1999-07, Vol.290 (1), p.182

1999

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SCREENING METHOD FOR URINARY BLADDER TUMOR DETECTION IN THE SYRIAN HAMSTER

Toxicology mechanisms and methods, 1999-04, Vol.9 (2), p.91-95

Feng, Timothy D. Rustan, Adrian J. Fretland, A. Marvin Cooley, Kap J. Lee, William K. Becker, David W. Hein, Yi

1999

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Metabolic activation of N-hydroxy-2-aminofluorene and N-hydroxy-2-acetylaminofluorene by monomorphic N-acetyltransferase (NAT1) and polymorphic N-acetyltransferase (NAT2) in colon cytosols of Syrian hamsters congenic at the NAT2 locus

Cancer research (Chicago, Ill.), 1993-02, Vol.53 (3), p.509-514

1993

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Rodent models of the human acetylation polymorphism: Comparisons of recombinant acetyltransferases

Mutation research, 1997-05, Vol.376 (1), p.101-106

1997

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Purification of hepatic polymorphic arylamine N-acetyltransferase from homozygous rapid acetylator inbred hamster: identity with polymorphic N-hydroxyarylamine-O-acetyltransferase

Cancer research (Chicago, Ill.), 1990-12, Vol.50 (24), p.7942-7949

1990

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Metabolic activation of aromatic and heterocyclic N-hydroxyarylamines by wild-type and mutant recombinant human NAT1 and NAT2 acetyltransferases

Archives of toxicology, 1994-02, Vol.68 (2), p.129-133

1994

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Identification of a novel allele at the human NAT1 acetyltransferase locus

Biochemical and biophysical research communications, 1997-04, Vol.233 (3), p.584-591

1997

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Higher Frequency of Aberrant Crypt Foci in Rapid Than Slow Acetylator Inbred Rats Administered the Colon Carcinogen 3,2′-Dimethyl-4-aminobiphenyl

Toxicology and applied pharmacology, 1997-11, Vol.147 (1), p.56-62

1997

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Human acetylator genotype : relationship to colorectal cancer incidence and arylamine N-acetyltransferase expression in colon cytosol

Archives of toxicology, 1993-08, Vol.67 (7), p.445-452

1993

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Acetyltransferases and susceptibility to chemicals

Toxicology letters, 1992-12, Vol.64, p.123-130

1992

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Construction of Syrian Hamster Lines Congenic at the Polymorphic Acetyltransferase Locus ( NAT2): Acetylator Genotype-Dependent N- and O-Acetylation of Arylamine Carcinogens

Toxicology and applied pharmacology, 1994, Vol.124 (1), p.16-24

1994

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Identification of a Novel Allele at the HumanNAT1Acetyltransferase Locus

Biochemical and biophysical research communications, 1997-04, Vol.233 (3), p.584-591

1997

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Acetylator Genotype-Dependent Formation of 2-Aminofluorene-Hemoglobin Adducts in Rapid and Slow Acetylator Syrian Hamsters Congenic at the NAT2 Locus

Toxicology and applied pharmacology, 1994, Vol.124 (1), p.10-15

1994

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Metabolic activation of aromatic and heterocyclicN-hydroxyarylamines by wild-type and mutant recombinant human NAT1 and NAT2 acetyltransferases

Archives of toxicology, 1994-02, Vol.68 (2), p.129-133

1994

Volltextzugriff (PDF)

Acetylator genotype-dependent N-acetylation of arylamines in vivo and in vitro by hepatic and extrahepatic organ cytosols of Syrian hamsters congenic at the polymorphic acetyltransferase locus

Archives of toxicology, 1992, Vol.66 (2), p.112-117

1992

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A rapid and sensitive method for detection of urinary bladder tumors in rodents

Proceedings of the Western Pharmacology Society, 1998, Vol.41, p.11

1998

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Human brain tubulin purification: decrease in soluble tubulin with age

Neurochemical research, 1985, Vol.10 (1), p.1-18

1985

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Acetylator Genotype-Dependent Metabolic Activation of N-Hydroxy-2-Aminofluorene in Syrian Hamster Lines Congenic at the NAT2 Locus

Polycyclic aromatic compounds, 1994-08, Vol.7 (1-3), p.59-66

1994

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Cloning, expression, and functional characterization of rapid and slow acetylator polymorphic N-acetyl-transferase encoding genes of the Syrian hamster

Pharmacogenetics (London), 1996-02, Vol.6 (1), p.55-66

1996

Volltextzugriff (PDF)

Cloning, expression, and functional characterization of rapid and slow acetylator polymorphic N-acetyltransferase encoding genes of the Syrian hamster

Pharmacogenetics (London), 1996-02, Vol.6 (1), p.55-66

1996

Volltextzugriff (PDF)

Syrian hamster monomorphic N-acetyltransferase (NAT1) alleles: amplification, cloning, sequencing, and expression in E. coli

Pharmacogenetics (London), 1994-04, Vol.4 (2), p.82-90

1994

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Metabolic activation and deactivation of arylamine carcinogens by recombinant human NAT1 and polymorphic NAT2 acetyltransferases

Metabolic activation of N-hydroxyarylamines and N-hydroxyarylamides by 16 recombinant human NAT2 allozymes: effects of 7 specific NAT2 nucleic acid substitutions

Molecular genetics of human polymorphic N-acetyltransferase: enzymatic analysis of 15 recombinant wild-type, mutant, and chimeric NAT2 allozymes

Human N-acetylation of benzidine : Role of NAT1 and NAT2

Prostate-specific human N-acetyltransferase 2 (NAT2) expression in the mouse

SCREENING METHOD FOR URINARY BLADDER TUMOR DETECTION IN THE SYRIAN HAMSTER

Metabolic activation of N-hydroxy-2-aminofluorene and N-hydroxy-2-acetylaminofluorene by monomorphic N-acetyltransferase (NAT1) and polymorphic N-acetyltransferase (NAT2) in colon cytosols of Syrian hamsters congenic at the NAT2 locus

Rodent models of the human acetylation polymorphism: Comparisons of recombinant acetyltransferases

Purification of hepatic polymorphic arylamine N-acetyltransferase from homozygous rapid acetylator inbred hamster: identity with polymorphic N-hydroxyarylamine-O-acetyltransferase

Metabolic activation of aromatic and heterocyclic N-hydroxyarylamines by wild-type and mutant recombinant human NAT1 and NAT2 acetyltransferases

Identification of a novel allele at the human NAT1 acetyltransferase locus

Higher Frequency of Aberrant Crypt Foci in Rapid Than Slow Acetylator Inbred Rats Administered the Colon Carcinogen 3,2′-Dimethyl-4-aminobiphenyl

Human acetylator genotype : relationship to colorectal cancer incidence and arylamine N-acetyltransferase expression in colon cytosol

Acetyltransferases and susceptibility to chemicals

Construction of Syrian Hamster Lines Congenic at the Polymorphic Acetyltransferase Locus ( NAT2): Acetylator Genotype-Dependent N- and O-Acetylation of Arylamine Carcinogens

Identification of a Novel Allele at the HumanNAT1Acetyltransferase Locus

Acetylator Genotype-Dependent Formation of 2-Aminofluorene-Hemoglobin Adducts in Rapid and Slow Acetylator Syrian Hamsters Congenic at the NAT2 Locus

Metabolic activation of aromatic and heterocyclicN-hydroxyarylamines by wild-type and mutant recombinant human NAT1 and NAT2 acetyltransferases

Acetylator genotype-dependent N-acetylation of arylamines in vivo and in vitro by hepatic and extrahepatic organ cytosols of Syrian hamsters congenic at the polymorphic acetyltransferase locus

A rapid and sensitive method for detection of urinary bladder tumors in rodents

Human brain tubulin purification: decrease in soluble tubulin with age

Acetylator Genotype-Dependent Metabolic Activation of N-Hydroxy-2-Aminofluorene in Syrian Hamster Lines Congenic at the NAT2 Locus

Cloning, expression, and functional characterization of rapid and slow acetylator polymorphic N-acetyl-transferase encoding genes of the Syrian hamster

Cloning, expression, and functional characterization of rapid and slow acetylator polymorphic N-acetyltransferase encoding genes of the Syrian hamster

Syrian hamster monomorphic N-acetyltransferase (NAT1) alleles: amplification, cloning, sequencing, and expression in E. coli

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