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Epigenetic Memory and Preferential Lineage-Specific Differentiation in Induced Pluripotent Stem Cells Derived from Human Pancreatic Islet Beta Cells

Cell stem cell, 2011-07, Vol.9 (1), p.17-23

2011

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Human islets contain four distinct subtypes of β cells

Nature communications, 2016-07, Vol.7 (1), p.11756-11756, Article 11756

2016

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Human pancreatic beta-like cells converted from fibroblasts

Nature communications, 2016-01, Vol.7 (1), p.10080-10080, Article 10080

2016

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Replication confers β cell immaturity

Nature communications, 2018-02, Vol.9 (1), p.485-12, Article 485

2018

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Small Molecules Facilitate the Reprogramming of Mouse Fibroblasts into Pancreatic Lineages

Cell stem cell, 2014-02, Vol.14 (2), p.228-236

2014

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From the dish to humans: A stem cell recipe for success

Cell metabolism, 2022-02, Vol.34 (2), p.193-196

2022

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FMRP promotes RNA localization to neuronal projections through interactions between its RGG domain and G-quadruplex RNA sequences

eLife, 2020-06, Vol.9

2020

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Loss of the transcription factor MAFB limits β-cell derivation from human PSCs

Nature communications, 2020-06, Vol.11 (1), p.2742-2742, Article 2742

2020

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Sox9 regulates alternative splicing and pancreatic beta cell function

Nature communications, 2024-01, Vol.15 (1), p.588-588, Article 588

2024

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Generation of Functional Thymic Epithelium from Human Embryonic Stem Cells that Supports Host T Cell Development

Cell stem cell, 2013-08, Vol.13 (2), p.219-229

2013

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Epithelial-mesenchymal transition in cells expanded in vitro from lineage-traced adult human pancreatic beta cells

PloS one, 2009-07, Vol.4 (7), p.e6417-e6417

2009

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In Vitro Proliferation of Cells Derived From Adult Human β-Cells Revealed By Cell-Lineage Tracing

Diabetes (New York, N.Y.), 2008-06, Vol.57 (6), p.1575-1583

2008

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The chromatin regulator Brg1 suppresses formation of intraductal papillary mucinous neoplasm and pancreatic ductal adenocarcinoma

Nature cell biology, 2014-03, Vol.16 (3), p.255

2014

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Insulin-producing cells generated from dedifferentiated human pancreatic beta cells expanded in vitro

PloS one, 2011-09, Vol.6 (9), p.e25566

2011

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Protecting Stem Cell Derived Pancreatic Beta-Like Cells From Diabetogenic T Cell Recognition

Frontiers in endocrinology (Lausanne), 2021-07, Vol.12, p.707881-707881

2021

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Cell Replacement Therapy for Type 1 Diabetes Patients: Potential Mechanisms Leading to Stem-Cell-Derived Pancreatic β-Cell Loss upon Transplant

Cells (Basel, Switzerland), 2023-02, Vol.12 (5), p.698

2023

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The beta cell-immune cell interface in type 1 diabetes (T1D)

Molecular metabolism (Germany), 2023-12, Vol.78, p.101809-101809, Article 101809

2023

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Human stem cell derived beta-like cells engineered to present PD-L1 improve transplant survival in NOD mice carrying human HLA class I

Frontiers in endocrinology (Lausanne), 2022-11, Vol.13, p.989815-989815

2022

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Proinsulin-Reactive CD4 T Cells in the Islets of Type 1 Diabetes Organ Donors

Frontiers in endocrinology (Lausanne), 2021-03, Vol.12, p.622647-622647

2021

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Stem cell-based multi-tissue platforms to model human autoimmune diabetes

Molecular metabolism (Germany), 2022-12, Vol.66, p.101610-101610, Article 101610

2022

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Mitigating Ischemic Injury of Stem Cell-Derived Insulin-Producing Cells after Transplant

Stem cell reports, 2017-09, Vol.9 (3), p.807-819

2017

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Stem-Cell-Derived β-Like Cells with a Functional PTPN2 Knockout Display Increased Immunogenicity

Cells (Basel, Switzerland), 2022-11, Vol.11 (23), p.3845

2022

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Recapitulating endocrine cell clustering in culture promotes maturation of human stem-cell-derived β cells

Nature cell biology, 2019-02, Vol.21 (2), p.263

2019

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Controlled induction of human pancreatic progenitors produces functional beta-like cells in vitro

The EMBO journal, 2015-07, Vol.34 (13), p.1759-1772

2015

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Regulatory approval of islet transplantation for treatment of type 1 diabetes: Implications and what is on the horizon

Molecular therapy, 2023-11, Vol.31 (11), p.3107-3108

2023

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Epigenetic Memory and Preferential Lineage-Specific Differentiation in Induced Pluripotent Stem Cells Derived from Human Pancreatic Islet Beta Cells

Human islets contain four distinct subtypes of β cells

Human pancreatic beta-like cells converted from fibroblasts

Replication confers β cell immaturity

Small Molecules Facilitate the Reprogramming of Mouse Fibroblasts into Pancreatic Lineages

From the dish to humans: A stem cell recipe for success

FMRP promotes RNA localization to neuronal projections through interactions between its RGG domain and G-quadruplex RNA sequences

Loss of the transcription factor MAFB limits β-cell derivation from human PSCs

Sox9 regulates alternative splicing and pancreatic beta cell function

Generation of Functional Thymic Epithelium from Human Embryonic Stem Cells that Supports Host T Cell Development

Epithelial-mesenchymal transition in cells expanded in vitro from lineage-traced adult human pancreatic beta cells

In Vitro Proliferation of Cells Derived From Adult Human β-Cells Revealed By Cell-Lineage Tracing

The chromatin regulator Brg1 suppresses formation of intraductal papillary mucinous neoplasm and pancreatic ductal adenocarcinoma

Insulin-producing cells generated from dedifferentiated human pancreatic beta cells expanded in vitro

Protecting Stem Cell Derived Pancreatic Beta-Like Cells From Diabetogenic T Cell Recognition

Cell Replacement Therapy for Type 1 Diabetes Patients: Potential Mechanisms Leading to Stem-Cell-Derived Pancreatic β-Cell Loss upon Transplant

The beta cell-immune cell interface in type 1 diabetes (T1D)

Human stem cell derived beta-like cells engineered to present PD-L1 improve transplant survival in NOD mice carrying human HLA class I

Proinsulin-Reactive CD4 T Cells in the Islets of Type 1 Diabetes Organ Donors

Stem cell-based multi-tissue platforms to model human autoimmune diabetes

Mitigating Ischemic Injury of Stem Cell-Derived Insulin-Producing Cells after Transplant

Stem-Cell-Derived β-Like Cells with a Functional PTPN2 Knockout Display Increased Immunogenicity

Recapitulating endocrine cell clustering in culture promotes maturation of human stem-cell-derived β cells

Controlled induction of human pancreatic progenitors produces functional beta-like cells in vitro

Regulatory approval of islet transplantation for treatment of type 1 diabetes: Implications and what is on the horizon

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