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The antioxidant responsive element. Activation by oxidative stress and identification of the DNA consensus sequence required for functional activity

The Journal of biological chemistry, 1991-06, Vol.266 (18), p.11632-11639

1991

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Transcriptional regulation of the rat glutathione S-transferase Ya subunit gene. Characterization of a xenobiotic-responsive element controlling inducible expression by phenolic antioxidants

The Journal of biological chemistry, 1990-08, Vol.265 (24), p.14648-14653

1990

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Cloning and expression of a cDNA for the human prostanoid FP receptor

The Journal of biological chemistry, 1994-01, Vol.269 (4), p.2632-2636

1994

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Cloning and expression of a cDNA for the human prostanoid IP receptor

The Journal of biological chemistry, 1994-04, Vol.269 (16), p.12173-12178

1994

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Compendium of gene expression profiles comprising a baseline model of the human liver drug metabolism transcriptome

Xenobiotica, 2006-10, Vol.36 (10-11), p.938-962

2006

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Regulation of Glutathione S-Transferase Ya Subunit Gene Expression: Identification of a Unique Xenobiotic-Responsive Element Controlling Inducible Expression by Planar Aromatic Compounds

Proceedings of the National Academy of Sciences - PNAS, 1990-05, Vol.87 (10), p.3826-3830

1990

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Studies on cytochrome P-450-mediated bioactivation of diclofenac in rats and in human hepatocytes: identification of glutathione conjugated metabolites

Drug metabolism and disposition, 1999-03, Vol.27 (3), p.365

1999

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Transcriptional regulation of a rat liver glutathione S-transferase Ya subunit gene. Analysis of the antioxidant response element and its activation by the phorbol ester 12-O-tetradecanoylphorbol-13-acetate

The Journal of biological chemistry, 1994-05, Vol.269 (18), p.13656-13662

1994

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An invasive cleavage assay for direct quantitation of specific RNAs

Nature biotechnology, 2001-07, Vol.19 (7), p.673-676

2001

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Substrate inhibition kinetics for cytochrome P450-catalyzed reactions

Drug metabolism and disposition, 2001-04, Vol.29 (4 Pt 1), p.368

2001

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Major role of human liver microsomal cytochrome P450 2C9 (CYP2C9) in the oxidative metabolism of celecoxib, a novel cyclooxygenase-II inhibitor

The Journal of pharmacology and experimental therapeutics, 2000-05, Vol.293 (2), p.453

2000

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Glutathione S-transferases, structure, regulation, and therapeutic implications

The Journal of biological chemistry, 1993-06, Vol.268 (16), p.11475-11478

1993

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A Kinetic Model for the Metabolic Interaction of Two Substrates at the Active Site of Cytochrome P450 3A4

The Journal of biological chemistry, 2001-01, Vol.276 (3), p.2256-2262

2001

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Inhibition of hepatocarcinogenic responses to 1,2-dimethylhydrazine by diallyl sulfide, a component of garlic oil

Carcinogenesis (New York), 1987-08, Vol.8 (8), p.1155-1157

1987

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Pathogenesis of skin and liver neoplasms in white suckers from industrially polluted areas in Lake Ontario

The Science of the total environment, 1990-05, Vol.94 (1), p.105-123

1990

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Sigmoidal kinetic model for two co-operative substrate-binding sites in a cytochrome P450 3A4 active site: an example of the metabolism of diazepam and its derivatives

Biochemical journal, 1999-06, Vol.340 ( Pt 3) (3), p.845-853

1999

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Rapid lipid peroxidation in the nuclear fraction of rat liver induced by a diet deficient in choline and methionine

Cancer letters, 1984-01, Vol.24 (3), p.251-255

1984

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Protective activity of different hepatic cytosolic glutathione S-transferases against DNA-binding metabolites of aflatoxin B1

Toxicology and applied pharmacology, 1990-09, Vol.105 (3), p.351-363

1990

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Transcription regulation of rat glutathione S-transferase Ya subunit gene expression by chemopreventive agents

Pharmaceutical research, 1996-07, Vol.13 (7), p.1043-1048

1996

Volltextzugriff (PDF)

Enzyme kinetics of cytochrome P450-mediated reactions

Current drug metabolism, 2001-03, Vol.2 (1), p.17

2001

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Electrospray Ionization Mass Spectrometric Analysis of Intact Cytochrome P450: Identification of Tienilic Acid Adducts to P450 2C9

Biochemistry (Easton), 1999-02, Vol.38 (8), p.2312-2319

1999

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Enantioselective activation of the peroxisome proliferator-activated receptor

The Journal of biological chemistry, 1993-03, Vol.268 (8), p.5530-5534

1993

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Bioreactor Systems in Drug Metabolism: Synthesis of Cytochrome P450-Generated Metabolites

Metabolic engineering, 2000-04, Vol.2 (2), p.115-125

2000

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Cloning and expression of three isoforms of the human EP3 prostanoid receptor

FEBS letters, 1994-01, Vol.338 (2), p.170-174

1994

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Halothane-Induced Liver Injury in Outbred Guinea Pigs: Role of Trifluoroacetylated Protein Adducts in Animal Susceptibility

Chemical research in toxicology, 2001-04, Vol.14 (4), p.362-370

2001

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The antioxidant responsive element. Activation by oxidative stress and identification of the DNA consensus sequence required for functional activity

Transcriptional regulation of the rat glutathione S-transferase Ya subunit gene. Characterization of a xenobiotic-responsive element controlling inducible expression by phenolic antioxidants

Cloning and expression of a cDNA for the human prostanoid FP receptor

Cloning and expression of a cDNA for the human prostanoid IP receptor

Compendium of gene expression profiles comprising a baseline model of the human liver drug metabolism transcriptome

Regulation of Glutathione S-Transferase Ya Subunit Gene Expression: Identification of a Unique Xenobiotic-Responsive Element Controlling Inducible Expression by Planar Aromatic Compounds

Studies on cytochrome P-450-mediated bioactivation of diclofenac in rats and in human hepatocytes: identification of glutathione conjugated metabolites

Transcriptional regulation of a rat liver glutathione S-transferase Ya subunit gene. Analysis of the antioxidant response element and its activation by the phorbol ester 12-O-tetradecanoylphorbol-13-acetate

An invasive cleavage assay for direct quantitation of specific RNAs

Substrate inhibition kinetics for cytochrome P450-catalyzed reactions

Major role of human liver microsomal cytochrome P450 2C9 (CYP2C9) in the oxidative metabolism of celecoxib, a novel cyclooxygenase-II inhibitor

Glutathione S-transferases, structure, regulation, and therapeutic implications

A Kinetic Model for the Metabolic Interaction of Two Substrates at the Active Site of Cytochrome P450 3A4

Inhibition of hepatocarcinogenic responses to 1,2-dimethylhydrazine by diallyl sulfide, a component of garlic oil

Pathogenesis of skin and liver neoplasms in white suckers from industrially polluted areas in Lake Ontario

Sigmoidal kinetic model for two co-operative substrate-binding sites in a cytochrome P450 3A4 active site: an example of the metabolism of diazepam and its derivatives

Rapid lipid peroxidation in the nuclear fraction of rat liver induced by a diet deficient in choline and methionine

Protective activity of different hepatic cytosolic glutathione S-transferases against DNA-binding metabolites of aflatoxin B1

Transcription regulation of rat glutathione S-transferase Ya subunit gene expression by chemopreventive agents

Enzyme kinetics of cytochrome P450-mediated reactions

Electrospray Ionization Mass Spectrometric Analysis of Intact Cytochrome P450: Identification of Tienilic Acid Adducts to P450 2C9

Enantioselective activation of the peroxisome proliferator-activated receptor

Bioreactor Systems in Drug Metabolism: Synthesis of Cytochrome P450-Generated Metabolites

Cloning and expression of three isoforms of the human EP3 prostanoid receptor

Halothane-Induced Liver Injury in Outbred Guinea Pigs: Role of Trifluoroacetylated Protein Adducts in Animal Susceptibility

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