UB Paderborn / Katalog / Suche / in CDI

1 – 25 von 577

Sortiert nach

A Shape-Based 3-D Scaffold Hopping Method and Its Application to a Bacterial Protein−Protein Interaction

Journal of medicinal chemistry, 2005-03, Vol.48 (5), p.1489-1495

2005

Volltextzugriff (PDF)

Functional, Biophysical, and Structural Bases for Antibacterial Activity of Tigecycline

Antimicrobial Agents and Chemotherapy, 2006-06, Vol.50 (6), p.2156-2166

2006

Volltextzugriff (PDF)

Rethinking drug design in the artificial intelligence era

Nature reviews. Drug discovery, 2020-05, Vol.19 (5), p.353-364

2020

Volltextzugriff (PDF)

The Role of Helix 1 Aspartates and Salt Bridges in the Stability and Conversion of Prion Protein

The Journal of biological chemistry, 2003-04, Vol.278 (14), p.12522-12529

2003

Volltextzugriff (PDF)

Potent, selective, and orally bioavailable matrix metalloproteinase-13 inhibitors for the treatment of osteoarthritis

Bioorganic & medicinal chemistry, 2005-12, Vol.13 (24), p.6629-6644

2005

Volltextzugriff (PDF)

Discovery of novel inhibitors of the ZipA/FtsZ complex by NMR fragment screening coupled with structure-based design

Bioorganic & medicinal chemistry, 2006-12, Vol.14 (23), p.7953-7961

2006

Volltextzugriff (PDF)

Machine Learning Models to Predict Inhibition of the Bile Salt Export Pump

Journal of chemical information and modeling, 2021-02, Vol.61 (2), p.587-602

2021

Volltextzugriff (PDF)

Structure-based design of carboxybiphenylindole inhibitors of the ZipA-FtsZ interaction

Organic & biomolecular chemistry, 2003-12, Vol.1 (23), p.4138-4140

2003

Volltextzugriff (PDF)

Identification of potent and selective MMP-13 inhibitors

Bioorganic & medicinal chemistry letters, 2005-09, Vol.15 (18), p.4105-4109

2005

Volltextzugriff (PDF)

Design and synthesis of indolo[2,3- a]quinolizin-7-one inhibitors of the ZipA–FtsZ interaction

Bioorganic & medicinal chemistry letters, 2004-03, Vol.14 (6), p.1427-1431

2004

Volltextzugriff (PDF)

FeNO Structure in Distal Pocket Mutants of Myoglobin Based on Resonance Raman Spectroscopy

Biochemistry (Easton), 2003-05, Vol.42 (17), p.4896-4903

2003

Volltextzugriff (PDF)

Impact of Mobility on Structure-Based Drug Design for the MMPs

Journal of the American Chemical Society, 2002-10, Vol.124 (43), p.12658-12659

2002

Volltextzugriff (PDF)

Structure-Based Identification of the Binding Site for the Hemiasterlin Analogue HTI-286 on Tubulin

Biochemistry (Easton), 2005-12, Vol.44 (48), p.15871-15879

2005

Volltextzugriff (PDF)

IR spectra of cytochrome c denatured with deuterated guanidine hydrochloride show increase in β sheet

Biopolymers, 2003, Vol.72 (3), p.193-204

2003

Volltextzugriff (PDF)

Synthesis and SAR of highly selective MMP-13 inhibitors

Bioorganic & medicinal chemistry letters, 2005-11, Vol.15 (22), p.4961-4966

2005

Volltextzugriff (PDF)

The application of x-ray, NMR, and molecular modeling in the design of MMP inhibitors

Current topics in medicinal chemistry, 2004-01, Vol.4 (12), p.1311

2004

Volltextzugriff (PDF)

3,4-Disubstituted benzofuran P1′ MMP-13 inhibitors: Optimization of selectivity and reduction of protein binding

Bioorganic & medicinal chemistry letters, 2009-08, Vol.19 (16), p.4546-4550

2009

Volltextzugriff (PDF)

Combinatorial synthesis of substituted 3-(2-indolyl)piperidines and 2-phenyl indoles as inhibitors of ZipA–FtsZ interaction

Bioorganic & medicinal chemistry, 2004-10, Vol.12 (19), p.5115-5131

2004

Volltextzugriff (PDF)

Alternative Modes of Substrate Distortion in Enzyme and Antibody Catalyzed Ferrochelation Reactions

Biochemistry (Easton), 1998-01, Vol.37 (3), p.779-782

1998

Volltextzugriff (PDF)

Resonance Raman Spectra of Ferrochelatase Reveal Porphyrin Distortion upon Metal Binding

Journal of the American Chemical Society, 1997-12, Vol.119 (50), p.12170-12174

1997

Volltextzugriff (PDF)

Computational Modeling of Metalloporphyrin Structure and Vibrational Spectra: Porphyrin Ruffling in NiTPP

The journal of physical chemistry. B, 2000-05, Vol.104 (20), p.5020-5034

2000

Volltextzugriff (PDF)

Synthesis and biological evaluation of biphenylsulfonamide carboxylate aggrecanase-1 inhibitors

Bioorganic & medicinal chemistry letters, 2006-01, Vol.16 (2), p.311-316

2006

Volltextzugriff (PDF)

Machine Learning Models to Predict Inhibition of the Bile Salt Export Pump

Journal of chemical information and modeling, 2021-01, Vol.61 (2)

2021

Volltextzugriff (PDF)

Simulation of Non-Condon Enhancement and Interference Effects in the Resonance Raman Intensities of Metalloporphyrins

The journal of physical chemistry. B, 1998-09, Vol.102 (37), p.7280-7286

1998

Volltextzugriff (PDF)

1 – 25 von 577

Suche als RSS-Feed

Suchergebnisse filtern

Filter anzeigen

Nur zeigen

Geprüft (Peer-Review)
(487)
Mit Volltextzugriff
(480)

Publikationsform

4 weitere anzeigen...

Weniger anzeigen...

Sprache

Erscheinungsjahr

n.n

Thema

Science & Technology
(353)
Life Sciences & Biomedicine
(318)
Humans
(241)
Male
(181)
Female
(164)
Biological And Medical Sciences
(137)
Medical Sciences
(120)
Adult
(108)
Psychiatry
(93)
Middle Aged
(82)
Animals
(74)
Aged
(63)
Psychology. Psychoanalysis. Psychiatry
(62)
Pharmacology. Drug Treatments
(51)
Treatment Outcome
(49)
Physical Sciences
(45)
Social Sciences
(45)
Adolescent
(42)
Pharmacology & Pharmacy
(42)
Chemistry
(38)

15 weitere anzeigen...

Weniger anzeigen...

Neu hinzugefügt

... seit 90 Tagen
(6)

Menü

Weitere Dienste

Einstellungen

A Shape-Based 3-D Scaffold Hopping Method and Its Application to a Bacterial Protein−Protein Interaction

Functional, Biophysical, and Structural Bases for Antibacterial Activity of Tigecycline

Development of MK-8353, an orally administered ERK1/2 inhibitor, in patients with advanced solid tumors

Rethinking drug design in the artificial intelligence era

The Role of Helix 1 Aspartates and Salt Bridges in the Stability and Conversion of Prion Protein

Potent, selective, and orally bioavailable matrix metalloproteinase-13 inhibitors for the treatment of osteoarthritis

Discovery of novel inhibitors of the ZipA/FtsZ complex by NMR fragment screening coupled with structure-based design

Machine Learning Models to Predict Inhibition of the Bile Salt Export Pump

Structure-based design of carboxybiphenylindole inhibitors of the ZipA-FtsZ interaction

Identification of potent and selective MMP-13 inhibitors

Design and synthesis of indolo[2,3- a]quinolizin-7-one inhibitors of the ZipA–FtsZ interaction

FeNO Structure in Distal Pocket Mutants of Myoglobin Based on Resonance Raman Spectroscopy

Impact of Mobility on Structure-Based Drug Design for the MMPs

Structure-Based Identification of the Binding Site for the Hemiasterlin Analogue HTI-286 on Tubulin

IR spectra of cytochrome c denatured with deuterated guanidine hydrochloride show increase in β sheet

Synthesis and SAR of highly selective MMP-13 inhibitors

The application of x-ray, NMR, and molecular modeling in the design of MMP inhibitors

3,4-Disubstituted benzofuran P1′ MMP-13 inhibitors: Optimization of selectivity and reduction of protein binding

Combinatorial synthesis of substituted 3-(2-indolyl)piperidines and 2-phenyl indoles as inhibitors of ZipA–FtsZ interaction

Alternative Modes of Substrate Distortion in Enzyme and Antibody Catalyzed Ferrochelation Reactions

Resonance Raman Spectra of Ferrochelatase Reveal Porphyrin Distortion upon Metal Binding

Computational Modeling of Metalloporphyrin Structure and Vibrational Spectra: Porphyrin Ruffling in NiTPP

Synthesis and biological evaluation of biphenylsulfonamide carboxylate aggrecanase-1 inhibitors

Machine Learning Models to Predict Inhibition of the Bile Salt Export Pump

Simulation of Non-Condon Enhancement and Interference Effects in the Resonance Raman Intensities of Metalloporphyrins

Suchergebnisse filtern