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Vitamin K-Dependent Protein Activation: Normal Gamma-Glutamyl Carboxylation and Disruption in Disease

International journal of molecular sciences, 2022-05, Vol.23 (10), p.5759

2022

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Ccq1 restrains Mre11-mediated degradation to distinguish short telomeres from double-strand breaks

Nucleic acids research, 2024-04, Vol.52 (7), p.3722

2024

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A multiplexed, three-dimensional pooling and next-generation sequencing strategy for creating barcoded mutant arrays: construction of a Schizosaccharomyces pombe transposon insertion library

Nucleic acids research, 2022-09, Vol.50 (17), p.e102

2022

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Identification of a lifespan extending mutation in the Schizosaccharomyces pombe cyclin gene clg1+ by direct selection of long-lived mutants

PloS one, 2013-07, Vol.8 (7), p.e69084

2013

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Telomere-binding proteins Taz1 and Rap1 regulate DSB repair and suppress gross chromosomal rearrangements in fission yeast

PLoS genetics, 2019-08, Vol.15 (8), p.e1008335-e1008335

2019

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The utility of a near-infrared spectrometer to predict the maturity of green peas (Pisum sativum)

Computers and electronics in agriculture, 2022-02, Vol.193, p.106643, Article 106643

2022

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Roles of putative Rho-GEF Gef2 in division-site positioning and contractile-ring function in fission yeast cytokinesis

Molecular biology of the cell, 2012-04, Vol.23 (7), p.1181-1195

2012

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The physiology of vitamin K nutriture and vitamin K‐dependent protein function in atherosclerosis

Journal of thrombosis and haemostasis, 2004-12, Vol.2 (12), p.2118-2132

2004

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Zinc finger protein Loz1 is required for zinc-responsive regulation of gene expression in fission yeast

Proceedings of the National Academy of Sciences - PNAS, 2013-09, Vol.110 (38), p.15371-15376

2013

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A proto-telomere is elongated by telomerase in a shelterin-dependent manner in quiescent fission yeast cells

Nucleic acids research, 2022-11, Vol.50 (20), p.11682

2022

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A curious new role for MRN in Schizosaccharomyces pombe non-homologous end-joining

Current genetics, 2018-04, Vol.64 (2), p.359-364

2018

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Commentary: Government Mandates, Unintended Consequences, and the Power of Prevention

Annals of emergency medicine, 2010-04, Vol.55 (4), p.374-377

Runge, Jeffrey W., MD

2010

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Warfarin alters vitamin K metabolism: a surprising mechanism of VKORC1 uncoupling necessitates an additional reductase

Blood, 2018-06, Vol.131 (25), p.2826-2835

2018

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GGCX mutants that impair hemostasis reveal the importance of processivity and full carboxylation to VKD protein function

Blood, 2022-10, Vol.140 (15), p.1710-1722

2022

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The inhibition of checkpoint activation by telomeres does not involve exclusion of dimethylation of histone H4 lysine 20 (H4K20me2) [version 2; peer review: 2 approved, 1 not approved]

F1000 research, 2018, Vol.7, p.1027

2018

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Generation and analysis of a barcode-tagged insertion mutant library in the fission yeast Schizosaccharomyces pombe

BMC genomics, 2012-05, Vol.13 (1), p.161-161, Article 161

2012

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new method to efficiently induce a site‐specific double‐strand break in the fission yeast Schizosaccharomyces pombe

Yeast (Chichester, England), 2012-07, Vol.29 (7), p.275-291

2012

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A two-step model for senescence triggered by a single critically short telomere

Nature cell biology, 2009-08, Vol.11 (8), p.988-993

2009

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Rif1 phosphorylation site analysis in telomere length regulation and the response to damaged telomeres

DNA repair, 2018-05, Vol.65, p.26-33

2018

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A Heterochromatin Domain Forms Gradually at a New Telomere and Is Dynamic at Stable Telomeres

Molecular and cellular biology, 2018-08, Vol.38 (15)

2018

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Exon 2 skipping eliminates γ‐glutamyl carboxylase activity, indicating a partial splicing defect in a patient with vitamin K clotting factor deficiency

Journal of thrombosis and haemostasis, 2019-07, Vol.17 (7), p.1053-1063

2019

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Sir3p phosphorylation by the Slt2p pathway effects redistribution of silencing function and shortened lifespan

Nature genetics, 2003-04, Vol.33 (4), p.522-526

2003

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Genetic approaches to aging in budding and fission yeasts: new connections and new opportunities

Sub-cellular biochemistry, 2012-01, Vol.57, p.291

2012

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The Yeast Telomere Length Counting Machinery Is Sensitive to Sequences at the Telomere-Nontelomere Junction

Molecular and Cellular Biology, 1999-01, Vol.19 (1), p.31-45

1999

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The Vitamin K Oxidoreductase Is a Multimer That Efficiently Reduces Vitamin K Epoxide to Hydroquinone to Allow Vitamin K-dependent Protein Carboxylation

The Journal of biological chemistry, 2013-11, Vol.288 (44), p.31556-31566

2013

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Vitamin K-Dependent Protein Activation: Normal Gamma-Glutamyl Carboxylation and Disruption in Disease

Ccq1 restrains Mre11-mediated degradation to distinguish short telomeres from double-strand breaks

A multiplexed, three-dimensional pooling and next-generation sequencing strategy for creating barcoded mutant arrays: construction of a Schizosaccharomyces pombe transposon insertion library

Identification of a lifespan extending mutation in the Schizosaccharomyces pombe cyclin gene clg1+ by direct selection of long-lived mutants

Telomere-binding proteins Taz1 and Rap1 regulate DSB repair and suppress gross chromosomal rearrangements in fission yeast

The utility of a near-infrared spectrometer to predict the maturity of green peas (Pisum sativum)

Roles of putative Rho-GEF Gef2 in division-site positioning and contractile-ring function in fission yeast cytokinesis

The physiology of vitamin K nutriture and vitamin K‐dependent protein function in atherosclerosis

Zinc finger protein Loz1 is required for zinc-responsive regulation of gene expression in fission yeast

A proto-telomere is elongated by telomerase in a shelterin-dependent manner in quiescent fission yeast cells

A curious new role for MRN in Schizosaccharomyces pombe non-homologous end-joining

Commentary: Government Mandates, Unintended Consequences, and the Power of Prevention

Warfarin alters vitamin K metabolism: a surprising mechanism of VKORC1 uncoupling necessitates an additional reductase

GGCX mutants that impair hemostasis reveal the importance of processivity and full carboxylation to VKD protein function

The inhibition of checkpoint activation by telomeres does not involve exclusion of dimethylation of histone H4 lysine 20 (H4K20me2) [version 2; peer review: 2 approved, 1 not approved]

Generation and analysis of a barcode-tagged insertion mutant library in the fission yeast Schizosaccharomyces pombe

new method to efficiently induce a site‐specific double‐strand break in the fission yeast Schizosaccharomyces pombe

A two-step model for senescence triggered by a single critically short telomere

Rif1 phosphorylation site analysis in telomere length regulation and the response to damaged telomeres

A Heterochromatin Domain Forms Gradually at a New Telomere and Is Dynamic at Stable Telomeres

Exon 2 skipping eliminates γ‐glutamyl carboxylase activity, indicating a partial splicing defect in a patient with vitamin K clotting factor deficiency

Sir3p phosphorylation by the Slt2p pathway effects redistribution of silencing function and shortened lifespan

Genetic approaches to aging in budding and fission yeasts: new connections and new opportunities

The Yeast Telomere Length Counting Machinery Is Sensitive to Sequences at the Telomere-Nontelomere Junction

The Vitamin K Oxidoreductase Is a Multimer That Efficiently Reduces Vitamin K Epoxide to Hydroquinone to Allow Vitamin K-dependent Protein Carboxylation

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