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Multi-organ system for the evaluation of efficacy and off-target toxicity of anticancer therapeutics

Science translational medicine, 2019-06, Vol.11 (497)

2019

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Validation of an adipose-liver human-on-a-chip model of NAFLD for preclinical therapeutic efficacy evaluation

Scientific reports, 2021-06, Vol.11 (1), p.13159-13159, Article 13159

2021

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A functional hiPSC-cortical neuron differentiation and maturation model and its application to neurological disorders

Stem cell reports, 2022-01, Vol.17 (1), p.96-109

2022

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Differential Monocyte Actuation in a Three‐Organ Functional Innate Immune System‐on‐a‐Chip

Advanced science, 2020-07, Vol.7 (13), p.2000323-n/a

2020

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Classical Complement Pathway Inhibition in a “Human‐On‐A‐Chip” Model of Autoimmune Demyelinating Neuropathies

Advanced therapeutics, 2022-06, Vol.5 (6), p.n/a

2022

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Functional myotube formation from adult rat satellite cells in a defined serum-free system

Biotechnology progress, 2015-07, Vol.31 (4), p.997-1003

2015

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A Functional Human-on-a-Chip Autoimmune Disease Model of Myasthenia Gravis for Development of Therapeutics

Frontiers in cell and developmental biology, 2021-11, Vol.9, p.745897-745897

2021

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Skeletal muscle tissue engineering: A maturation model promoting long-term survival of myotubes, structural development of the excitation–contraction coupling apparatus and neonatal myosin heavy chain expression

Biomaterials, 2009-10, Vol.30 (29), p.5392-5402

2009

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Tissue engineering the mechanosensory circuit of the stretch reflex arc: Sensory neuron innervation of intrafusal muscle fibers

Biomaterials, 2010-11, Vol.31 (32), p.8218-8227

2010

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Embryonic motoneuron-skeletal muscle co-culture in a defined system

Neuroscience, 2007-05, Vol.146 (2), p.481-488

2007

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Functional skeletal muscle model derived from SOD1-mutant ALS patient iPSCs recapitulates hallmarks of disease progression

Scientific reports, 2020-08, Vol.10 (1), p.14302-14302, Article 14302

2020

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A human induced pluripotent stem cell‐derived cortical neuron human‐on‐a chip system to study Aβ42 and tau‐induced pathophysiological effects on long‐term potentiation

Alzheimer's & dementia : translational research & clinical interventions, 2020, Vol.6 (1), p.n/a

2020

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Photolithographic Patterning of C2C12 Myotubes using Vitronectin as Growth Substrate in Serum-Free Medium

Biotechnology progress, 2007, Vol.23 (1), p.265-268

2007

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Total Skeletal Muscle PGC-1 Deficiency Uncouples Mitochondrial Derangements from Fiber Type Determination and Insulin Sensitivity

Cell metabolism, 2010-12, Vol.12 (6), p.633-642

2010

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Node of Ranvier formation on motoneurons in vitro

Biomaterials, 2009-07, Vol.30 (21), p.3567-3572

2009

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A defined long-term in vitro tissue engineered model of neuromuscular junctions

Biomaterials, 2010-06, Vol.31 (18), p.4880-4888

2010

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Tissue engineering intrafusal fibers: Dose- and time-dependent differentiation of nuclear bag fibers in a defined in vitro system using neuregulin 1- β -1

Biomaterials, 2008-03, Vol.29 (8), p.994-1004

2008

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Myelination and Node of Ranvier Formation in a Human Motoneuron–Schwann Cell Serum-Free Coculture

ACS chemical neuroscience, 2020-09, Vol.11 (17), p.2615-2623

2020

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Thermoacoustic instability: model-based optimal control designs and experimental validation

IEEE transactions on control systems technology, 2000-11, Vol.8 (6), p.905-918

2000

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The oxygen dependence of mitochondrial oxidative phosphorylation measured by a new optical method for measuring oxygen concentration

The Journal of biological chemistry, 1988-02, Vol.263 (6), p.2712-2718

1988

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An induced pluripotent stem cell-derived NMJ platform for study of the NGLY1-Congenital Disorder of Deglycosylation

Advanced therapeutics, 2022-11, Vol.5 (11)

2022

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Cellular energetics and the oxygen dependence of respiration in cardiac myocytes isolated from adult rat

The Journal of biological chemistry, 1990-09, Vol.265 (26), p.15392-15399

1990

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Myelination and node of Ranvier formation on sensory neurons in a defined in vitro system

In vitro cellular & developmental biology. Animal, 2013-09, Vol.49 (8), p.608-618

2013

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A human induced pluripotent stem cell-derived cortical neuron human-on-a chip system to study Aβ 42 and tau-induced pathophysiological effects on long-term potentiation

Alzheimer's & dementia : translational research & clinical interventions, 2020, Vol.6 (1), p.e12029

2020

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Oxygen pressure distribution in the heart in vivo and evaluation of the ischemic "border zone"

American journal of physiology. Heart and circulatory physiology, 1994-04, Vol.266 (4), p.H1676-H1680

1994

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Multi-organ system for the evaluation of efficacy and off-target toxicity of anticancer therapeutics

Validation of an adipose-liver human-on-a-chip model of NAFLD for preclinical therapeutic efficacy evaluation

A functional hiPSC-cortical neuron differentiation and maturation model and its application to neurological disorders

Differential Monocyte Actuation in a Three‐Organ Functional Innate Immune System‐on‐a‐Chip

Classical Complement Pathway Inhibition in a “Human‐On‐A‐Chip” Model of Autoimmune Demyelinating Neuropathies

Functional myotube formation from adult rat satellite cells in a defined serum-free system

A Functional Human-on-a-Chip Autoimmune Disease Model of Myasthenia Gravis for Development of Therapeutics

Skeletal muscle tissue engineering: A maturation model promoting long-term survival of myotubes, structural development of the excitation–contraction coupling apparatus and neonatal myosin heavy chain expression

Tissue engineering the mechanosensory circuit of the stretch reflex arc: Sensory neuron innervation of intrafusal muscle fibers

Embryonic motoneuron-skeletal muscle co-culture in a defined system

Functional skeletal muscle model derived from SOD1-mutant ALS patient iPSCs recapitulates hallmarks of disease progression

A human induced pluripotent stem cell‐derived cortical neuron human‐on‐a chip system to study Aβ42 and tau‐induced pathophysiological effects on long‐term potentiation

Photolithographic Patterning of C2C12 Myotubes using Vitronectin as Growth Substrate in Serum-Free Medium

Total Skeletal Muscle PGC-1 Deficiency Uncouples Mitochondrial Derangements from Fiber Type Determination and Insulin Sensitivity

Node of Ranvier formation on motoneurons in vitro

A defined long-term in vitro tissue engineered model of neuromuscular junctions

Tissue engineering intrafusal fibers: Dose- and time-dependent differentiation of nuclear bag fibers in a defined in vitro system using neuregulin 1- β -1

Myelination and Node of Ranvier Formation in a Human Motoneuron–Schwann Cell Serum-Free Coculture

Thermoacoustic instability: model-based optimal control designs and experimental validation

The oxygen dependence of mitochondrial oxidative phosphorylation measured by a new optical method for measuring oxygen concentration

An induced pluripotent stem cell-derived NMJ platform for study of the NGLY1-Congenital Disorder of Deglycosylation

Cellular energetics and the oxygen dependence of respiration in cardiac myocytes isolated from adult rat

Myelination and node of Ranvier formation on sensory neurons in a defined in vitro system

A human induced pluripotent stem cell-derived cortical neuron human-on-a chip system to study Aβ 42 and tau-induced pathophysiological effects on long-term potentiation

Oxygen pressure distribution in the heart in vivo and evaluation of the ischemic "border zone"

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