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Metabolism of lysergic acid diethylamide (LSD): an update

Drug metabolism reviews, 2019-07, Vol.51 (3), p.378-387

Libânio Osório Marta, Rui Filipe

2019

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Regulation of Aquaporin Functional Properties Mediated by the Antioxidant Effects of Natural Compounds

International journal of molecular sciences, 2017-12, Vol.18 (12), p.2665

2017

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Marrubium vulgare L. Leave Extract: Phytochemical Composition, Antioxidant and Wound Healing Properties

Molecules (Basel, Switzerland), 2017-10, Vol.22 (11), p.1851

2017

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Dual-Functioning Scaffolds for the Treatment of Spinal Cord Injury: Alginate Nanofibers Loaded with the Sigma 1 Receptor (S1R) Agonist RC-33 in Chitosan Films

Marine drugs, 2019-12, Vol.18 (1), p.21

2019

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Sigma Receptors as Endoplasmic Reticulum Stress "Gatekeepers" and their Modulators as Emerging New Weapons in the Fight Against Cancer

Frontiers in pharmacology, 2018-07, Vol.9, p.711-711

2018

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Setup and Validation of a Reliable Docking Protocol for the Development of Neuroprotective Agents by Targeting the Sigma-1 Receptor (S1R)

International journal of molecular sciences, 2020-10, Vol.21 (20), p.7708

2020

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PEG 400/Cerium Ammonium Nitrate Combined with Microwave-Assisted Synthesis for Rapid Access to Beta-Amino Ketones. An Easy-to-Use Protocol for Discovering New Hit Compounds

Molecules (Basel, Switzerland), 2018-03, Vol.23 (4), p.775

2018

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Novel Enantiopure Sigma Receptor Modulators: Quick (Semi-)Preparative Chiral Resolution via HPLC and Absolute Configuration Assignment

Molecules (Basel, Switzerland), 2016-09, Vol.21 (9), p.1210

2016

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Are sigma modulators an effective opportunity for cancer treatment? A patent overview (1996-2016)

Expert opinion on therapeutic patents, 2017-05, Vol.27 (5), p.565-578

2017

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Anti-tumor Efficacy Assessment of the Sigma Receptor Pan Modulator RC-106. A Promising Therapeutic Tool for Pancreatic Cancer

Frontiers in pharmacology, 2019-05, Vol.10, p.490-490

2019

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Exploring the RC-106 Chemical Space: Design and Synthesis of Novel (E)-1-(3-Arylbut-2-en-1-yl)-4-(Substituted) Piperazine Derivatives as Potential Anticancer Agents

Frontiers in chemistry, 2020-06, Vol.8, p.495-495

2020

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Vinca alkaloids and analogues as anti-cancer agents: Looking back, peering ahead

Bioorganic & medicinal chemistry letters, 2018-09, Vol.28 (17), p.2816-2826

2018

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Efficient Access to All‐Carbon Quaternary and Tertiary α‐Functionalized Homoallyl‐type Aldehydes from Ketones

Angewandte Chemie International Edition, 2017-10, Vol.56 (41), p.12677-12682

International ed. in English, 2017

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Synthesis of a drug discovery library for the identification of sigma receptors modulators

Biodiscovery, 2017-07, Vol.20, p.e14958-3

2017

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Sigma 1 receptor modulators as a new weapon against multiple sclerosis

Biodiscovery, 2017-07, Vol.20, p.e14565-3

2017

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Bitopic Sigma 1 Receptor Modulators to Shed Light on Molecular Mechanisms Underpinning Ligand Binding and Receptor Oligomerization

Journal of medicinal chemistry, 2021-10, Vol.64 (20), p.14997-15016

2021

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A practical guide for using lithium halocarbenoids in homologation reactions

Monatshefte für Chemie, 2018, Vol.149 (7), p.1285-1291

2018

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Approaches for multi-gram scale isolation of enantiomers for drug discovery

Expert opinion on drug discovery, 2017-12, Vol.12 (12), p.1253-1269

2017

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New Insights into the Opening of the Occluded Ligand-Binding Pocket of Sigma1 Receptor: Binding of a Novel Bivalent RC-33 Derivative

Journal of chemical information and modeling, 2020-02, Vol.60 (2), p.756-765

2020

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"Fit-for-purpose" development of analytical and (semi)preparative enantioselective high performance liquid and supercritical fluid chromatography for the access to a novel σ1 receptor agonist

Journal of pharmaceutical and biomedical analysis, 2016-01, Vol.118, p.363-369

2016

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Synthesis and biological evaluation of new aryl-alkyl(alkenyl)-4-benzylpiperidines, novel Sigma Receptor (SR) modulators, as potential anticancer-agents

European journal of medicinal chemistry, 2016-11, Vol.124, p.649-665

2016

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Gaining in pan-affinity towards sigma 1 and sigma 2 receptors. SAR studies on arylalkylamines

Bioorganic & medicinal chemistry, 2017-01, Vol.25 (1), p.11-19

2017

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Are sigma receptor modulators a weapon against multiple sclerosis disease?

Future medicinal chemistry, 2017-11, Vol.9 (17), p.2029-2051

2017

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Identification of dual Sigma1 receptor modulators/acetylcholinesterase inhibitors with antioxidant and neurotrophic properties, as neuroprotective agents

European journal of medicinal chemistry, 2018-10, Vol.158, p.353-370

2018

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Abstract 1129: Sigma receptors: Novel targets for the treatment of highly malignant tumors

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.1129-1129

2017

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Metabolism of lysergic acid diethylamide (LSD): an update

Regulation of Aquaporin Functional Properties Mediated by the Antioxidant Effects of Natural Compounds

Marrubium vulgare L. Leave Extract: Phytochemical Composition, Antioxidant and Wound Healing Properties

Dual-Functioning Scaffolds for the Treatment of Spinal Cord Injury: Alginate Nanofibers Loaded with the Sigma 1 Receptor (S1R) Agonist RC-33 in Chitosan Films

Sigma Receptors as Endoplasmic Reticulum Stress "Gatekeepers" and their Modulators as Emerging New Weapons in the Fight Against Cancer

Setup and Validation of a Reliable Docking Protocol for the Development of Neuroprotective Agents by Targeting the Sigma-1 Receptor (S1R)

PEG 400/Cerium Ammonium Nitrate Combined with Microwave-Assisted Synthesis for Rapid Access to Beta-Amino Ketones. An Easy-to-Use Protocol for Discovering New Hit Compounds

Novel Enantiopure Sigma Receptor Modulators: Quick (Semi-)Preparative Chiral Resolution via HPLC and Absolute Configuration Assignment

Are sigma modulators an effective opportunity for cancer treatment? A patent overview (1996-2016)

Anti-tumor Efficacy Assessment of the Sigma Receptor Pan Modulator RC-106. A Promising Therapeutic Tool for Pancreatic Cancer

Exploring the RC-106 Chemical Space: Design and Synthesis of Novel (E)-1-(3-Arylbut-2-en-1-yl)-4-(Substituted) Piperazine Derivatives as Potential Anticancer Agents

Vinca alkaloids and analogues as anti-cancer agents: Looking back, peering ahead

Efficient Access to All‐Carbon Quaternary and Tertiary α‐Functionalized Homoallyl‐type Aldehydes from Ketones

Synthesis of a drug discovery library for the identification of sigma receptors modulators

Sigma 1 receptor modulators as a new weapon against multiple sclerosis

Bitopic Sigma 1 Receptor Modulators to Shed Light on Molecular Mechanisms Underpinning Ligand Binding and Receptor Oligomerization

A practical guide for using lithium halocarbenoids in homologation reactions

Approaches for multi-gram scale isolation of enantiomers for drug discovery

New Insights into the Opening of the Occluded Ligand-Binding Pocket of Sigma1 Receptor: Binding of a Novel Bivalent RC-33 Derivative

"Fit-for-purpose" development of analytical and (semi)preparative enantioselective high performance liquid and supercritical fluid chromatography for the access to a novel σ1 receptor agonist

Synthesis and biological evaluation of new aryl-alkyl(alkenyl)-4-benzylpiperidines, novel Sigma Receptor (SR) modulators, as potential anticancer-agents

Gaining in pan-affinity towards sigma 1 and sigma 2 receptors. SAR studies on arylalkylamines

Are sigma receptor modulators a weapon against multiple sclerosis disease?

Identification of dual Sigma1 receptor modulators/acetylcholinesterase inhibitors with antioxidant and neurotrophic properties, as neuroprotective agents

Abstract 1129: Sigma receptors: Novel targets for the treatment of highly malignant tumors

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