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Discovery and SAR studies of 2-alkyl-3-phenyl-2,4,5,6,7,8-hexahydropyrazolo[3,4-d]azepines as 5-HT7/2 inhibitors leading to the identification of a clinical candidate

Bioorganic & medicinal chemistry letters, 2021-01, Vol.31, p.127669-127669, Article 127669

2021

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Novel methyl substituted 1-(5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)methanones are P2X7 antagonists

Bioorganic & medicinal chemistry letters, 2015-08, Vol.25 (16), p.3157-3163

2015

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Characterization of N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-3-(3-cyano-phenyl)-N-[1-(2-cyclopentyl-ethyl)-piperidin-4yl]acrylamide (JNJ-5207787), a small molecule antagonist of the neuropeptide Y Y2 receptor

The Journal of pharmacology and experimental therapeutics, 2004-03, Vol.308 (3), p.1130

2004

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Substituted 5,6-(Dihydropyrido[3,4‑d]pyrimidin-7(8H)‑yl)-methanones as P2X7 Antagonists

ACS chemical neuroscience, 2016-04, Vol.7 (4), p.498-504

2016

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Palladium-Catalyzed Coupling of Pyrazole Triflates with Arylboronic Acids

Journal of organic chemistry, 2005-05, Vol.70 (10), p.4188-4190

2005

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Novel tetrahydropyrido[3,2-c]pyrroles as 5-HT7 antagonists

Bioorganic & medicinal chemistry letters, 2011-01, Vol.21 (1), p.42-44

2011

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Novel substituted 4-phenyl-[1,3]dioxanes: potent and selective orexin receptor 2 (OX 2R) antagonists

Bioorganic & medicinal chemistry letters, 2004-08, Vol.14 (16), p.4225-4229

2004

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The discovery and synthesis of JNJ 31020028, a small molecule antagonist of the Neuropeptide Y Y2 receptor

Bioorganic & medicinal chemistry letters, 2011-09, Vol.21 (18), p.5552-5556

2011

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2-Alkyl-4-aryl-pyrimidine fused heterocycles as selective 5-HT2A antagonists

Bioorganic & medicinal chemistry letters, 2008-03, Vol.18 (6), p.2103-2108

2008

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Novel non-peptidic neuropeptide Y Y2 receptor antagonists

Bioorganic & medicinal chemistry letters, 2004-03, Vol.14 (5), p.1239-1242

2004

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Discovery and SAR studies of 2-alkyl-3-phenyl-2,4,5,6,7,8-hexahydropyrazolo[3,4-d]azepines as 5-HT 7/2 inhibitors leading to the identification of a clinical candidate

Bioorganic & medicinal chemistry letters, 2021-01, Vol.31, p.127669

2021

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Novel tetrahydropyrido[3,2-c]pyrroles as 5-HT sub(7) antagonists

Bioorganic & medicinal chemistry letters, 2011-01, Vol.21 (1), p.42-44

2011

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The discovery and synthesis of JNJ 31020028, a small molecule antagonist of the Neuropeptide Y Y sub(2) receptor

Bioorganic & medicinal chemistry letters, 2011-09, Vol.21 (18), p.5552-5556

2011

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Corrigendum to “2-Alkyl-4-aryl-pyrimidine fused heterocycles as selective 5-HT2A antagonists” [Bioorg. Med. Chem. Lett. 18 (2008) 2103–2108]

Bioorganic & medicinal chemistry letters, 2008-07, Vol.18 (14), p.4253

2008

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2-Alkyl-4-aryl-pyrimidine fused heterocycles as selective 5-HT 2A antagonists

Bioorganic & medicinal chemistry letters, 2008, Vol.18 (6), p.2103-2108

2008

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Corrigendum to “2-Alkyl-4-aryl-pyrimidine fused heterocycles as selective 5-HT 2A antagonists” [Bioorg. Med. Chem. Lett. 18 (2008) 2103–2108]

Bioorganic & medicinal chemistry letters, 2008, Vol.18 (14), p.4253-4253

2008

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Novel tetrahydropyrido[3,2-c]pyrroles as 5-HT(7) antagonists

Bioorganic & medicinal chemistry letters, 2011-01, Vol.21 (1), p.42-44

2011

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Novel substituted 4-phenyl-[1,3]dioxanes: potent and selective orexin receptor 2 (OX(2)R) antagonists

Bioorganic & medicinal chemistry letters, 2004-08, Vol.14 (16), p.4225-4229

2004

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Novel non-peptidic neuropeptide Y Y 2 receptor antagonists

Bioorganic & medicinal chemistry letters, 2004-03, Vol.14 (5), p.1239-1242

2004

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Palladium-Catalyzed Coupling of Pyrazole Triflates with Arylboronic Acids

ChemInform, 2005-10, Vol.36 (42), p.no-no

2005

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Novel Substituted 4-Phenyl-[1,3]dioxanes: Potent and Selective Orexin Receptor 2 (OX2R) Antagonists

ChemInform, 2004-12, Vol.35 (50), p.no-no

2004

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The Glucose Transporter Glut1 Is Selectively Essential for CD4 T Cell Activation and Effector Function

Cell metabolism, 2014-07, Vol.20 (1), p.61-72

2014

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Modulation of glucose transporter 1 (GLUT1) expression levels alters mouse mammary tumor cell growth in vitro and in vivo

PloS one, 2011-08, Vol.6 (8), p.e23205-e23205

2011

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Provable quantum advantage in randomness processing

Nature communications, 2015-09, Vol.6 (1), p.8203-8203, Article 8203

2015

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Sleep health among US Navy afloat versus ashore personnel in the Millennium Cohort Study

Journal of sleep research, 2024-05, p.e14207-e14207

2024

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Discovery and SAR studies of 2-alkyl-3-phenyl-2,4,5,6,7,8-hexahydropyrazolo[3,4-d]azepines as 5-HT7/2 inhibitors leading to the identification of a clinical candidate

Novel methyl substituted 1-(5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)methanones are P2X7 antagonists

Characterization of N-(1-Acetyl-2,3-dihydro-1H-indol-6-yl)-3-(3-cyano-phenyl)-N-[1-(2-cyclopentyl-ethyl)-piperidin-4yl]acrylamide (JNJ-5207787), a small molecule antagonist of the neuropeptide Y Y2 receptor

Substituted 5,6-(Dihydropyrido[3,4‑d]pyrimidin-7(8H)‑yl)-methanones as P2X7 Antagonists

Palladium-Catalyzed Coupling of Pyrazole Triflates with Arylboronic Acids

Novel tetrahydropyrido[3,2-c]pyrroles as 5-HT7 antagonists

Novel substituted 4-phenyl-[1,3]dioxanes: potent and selective orexin receptor 2 (OX 2R) antagonists

The discovery and synthesis of JNJ 31020028, a small molecule antagonist of the Neuropeptide Y Y2 receptor

2-Alkyl-4-aryl-pyrimidine fused heterocycles as selective 5-HT2A antagonists

Novel non-peptidic neuropeptide Y Y2 receptor antagonists

Discovery and SAR studies of 2-alkyl-3-phenyl-2,4,5,6,7,8-hexahydropyrazolo[3,4-d]azepines as 5-HT 7/2 inhibitors leading to the identification of a clinical candidate

Novel tetrahydropyrido[3,2-c]pyrroles as 5-HT sub(7) antagonists

The discovery and synthesis of JNJ 31020028, a small molecule antagonist of the Neuropeptide Y Y sub(2) receptor

Corrigendum to “2-Alkyl-4-aryl-pyrimidine fused heterocycles as selective 5-HT2A antagonists” [Bioorg. Med. Chem. Lett. 18 (2008) 2103–2108]

2-Alkyl-4-aryl-pyrimidine fused heterocycles as selective 5-HT 2A antagonists

Corrigendum to “2-Alkyl-4-aryl-pyrimidine fused heterocycles as selective 5-HT 2A antagonists” [Bioorg. Med. Chem. Lett. 18 (2008) 2103–2108]

Novel tetrahydropyrido[3,2-c]pyrroles as 5-HT(7) antagonists

Novel substituted 4-phenyl-[1,3]dioxanes: potent and selective orexin receptor 2 (OX(2)R) antagonists

Novel non-peptidic neuropeptide Y Y 2 receptor antagonists

Palladium-Catalyzed Coupling of Pyrazole Triflates with Arylboronic Acids

Novel Substituted 4-Phenyl-[1,3]dioxanes: Potent and Selective Orexin Receptor 2 (OX2R) Antagonists

The Glucose Transporter Glut1 Is Selectively Essential for CD4 T Cell Activation and Effector Function

Modulation of glucose transporter 1 (GLUT1) expression levels alters mouse mammary tumor cell growth in vitro and in vivo

Provable quantum advantage in randomness processing

Sleep health among US Navy afloat versus ashore personnel in the Millennium Cohort Study

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