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On-target and Off-target-based Toxicologic Effects

Toxicologic pathology, 2013-02, Vol.41 (2), p.310-314

Rudmann, Daniel G.

2013

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The Emergence of Microphysiological Systems (Organs-on-chips) as Paradigm-changing Tools for Toxicologic Pathology

Toxicologic Pathology, 2019-01, Vol.47 (1), p.4-10

Rudmann, Daniel G.

2019

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ADVANCING NON-CLINICAL PATHOLOGY USING DECISION SUPPORT DEEP LEARNING

Journal of pathology informatics, 2022, Vol.13, p.100028, Article 100028

Rudmann, Daniel

2022

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The Gold Standard Paradox in Digital Image Analysis: Manual Versus Automated Scoring as Ground Truth

Archives of pathology & laboratory medicine (1976), 2017-09, Vol.141 (9), p.1267-1275

2017

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High Molecular Weight Polyethylene Glycol Cellular Distribution and PEG-associated Cytoplasmic Vacuolation Is Molecular Weight Dependent and Does Not Require Conjugation to Proteins

Toxicologic pathology, 2013-10, Vol.41 (7), p.970-983

2013

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Response to Letter to the Editor Regarding “Interstitial Adipocytes in the Beagle Dog and New Zealand White Rabbit Choroid Plexus”

Toxicologic pathology, 2019-10, Vol.47 (7), p.901-901

2019

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Interstitial Adipocytes in the Beagle Dog and New Zealand White Rabbit Choroid Plexus

Toxicologic pathology, 2019-06, Vol.47 (4), p.553-555

2019

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Mini Review: The Last Mile—Opportunities and Challenges for Machine Learning in Digital Toxicologic Pathology

Toxicologic Pathology, 2021-06, Vol.49 (4), p.714-719

2021

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Tailored Pig Models for Preclinical Efficacy and Safety Testing of Targeted Therapies

Toxicologic pathology, 2016-04, Vol.44 (3), p.346-357

2016

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Society of Toxicologic Pathology Digital Pathology and Image Analysis Special Interest Group Article: Opinion on the Application of Artificial Intelligence and Machine Learning to Digital Toxicologic Pathology

Toxicologic pathology, 2020-02, Vol.48 (2), p.277-294

2020

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Duchenne and Becker Muscular Dystrophies: A Review of Animal Models, Clinical End Points, and Biomarker Quantification

Toxicologic pathology, 2017-10, Vol.45 (7), p.961-976

2017

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Validation of a Muscle-Specific Tissue Image Analysis Tool for Quantitative Assessment of Dystrophin Staining in Frozen Muscle Biopsies

Archives of pathology & laboratory medicine (1976), 2019-02, Vol.143 (2), p.197-205

2019

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Proliferative and Nonproliferative Lesions of the Rat and Mouse Mammary, Zymbal’s, Preputial, and Clitoral Glands

Toxicologic pathology, 2012-08, Vol.40 (6_suppl), p.7S-39S

2012

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Using Automated Image Analysis Algorithms to Distinguish Normal, Aberrant, and Degenerate Mitotic Figures Induced by Eg5 Inhibition

Toxicologic pathology, 2016-07, Vol.44 (5), p.663-672

2016

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The Rat Mammary Gland: Morphologic Changes as an Indicator of Systemic Hormonal Perturbations Induced by Xenobiotics

Toxicologic Pathology, 2007-02, Vol.35 (2), p.199-207

2007

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Rat-Specific Decreases in Platelet Count Caused by a Humanized Monoclonal Antibody Against Sclerostin

Toxicological sciences, 2012-02, Vol.125 (2), p.586-594

2012

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Qualification of Cardiac Troponin I Concentration in Mouse Serum Using Isoproterenol and Implementation in Pharmacology Studies to Accelerate Drug Development

Toxicologic pathology, 2009-08, Vol.37 (5), p.617-628

2009

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Developing a Qualification and Verification Strategy for Digital Tissue Image Analysis in Toxicological Pathology

Toxicologic pathology, 2021-06, Vol.49 (4), p.773-783

2021

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A Selective Estrogen Receptor Modulator Designed for the Treatment of Uterine Leiomyoma with Unique Tissue Specificity for Uterus and Ovaries in Rats

Journal of medicinal chemistry, 2005-11, Vol.48 (22), p.6772-6775

2005

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A New Selective Estrogen Receptor Modulator with Potent Uterine Antagonist Activity, Agonist Activity in Bone, and Minimal Ovarian Stimulation

Endocrinology (Philadelphia), 2005-10, Vol.146 (10), p.4524-4535

2005

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Modulation of allergic inflammation in mice deficient in TNF receptors

American journal of physiology. Lung cellular and molecular physiology, 2000-12, Vol.279 (6), p.1047-L1057

2000

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Androgen Dependent Mammary Gland Virilism in Rats Given the Selective Estrogen Receptor Modulator LY2066948 Hydrochloride

Toxicologic pathology, 2005-10, Vol.33 (6), p.711-719

2005

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Using Deep Learning Artificial Intelligence Algorithms to Verify N-Nitroso-N-Methylurea and Urethane Positive Control Proliferative Changes in Tg-RasH2 Mouse Carcinogenicity Studies

Toxicologic pathology, 2021-06, Vol.49 (4), p.938-949

2021

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Utilization of Genetically Altered Animals in the Pharmaceutical Industry

Toxicologic pathology, 1999-01, Vol.27 (1), p.111-114

1999

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Proposal to Eliminate Urethane-Treated Positive Control Dose Groups in 26-Week Tg.rasH2 Carcinogenicity Studies

International journal of toxicology, 2021-05, Vol.40 (3), p.207-210

2021

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On-target and Off-target-based Toxicologic Effects

The Emergence of Microphysiological Systems (Organs-on-chips) as Paradigm-changing Tools for Toxicologic Pathology

ADVANCING NON-CLINICAL PATHOLOGY USING DECISION SUPPORT DEEP LEARNING

The Gold Standard Paradox in Digital Image Analysis: Manual Versus Automated Scoring as Ground Truth

High Molecular Weight Polyethylene Glycol Cellular Distribution and PEG-associated Cytoplasmic Vacuolation Is Molecular Weight Dependent and Does Not Require Conjugation to Proteins

Response to Letter to the Editor Regarding “Interstitial Adipocytes in the Beagle Dog and New Zealand White Rabbit Choroid Plexus”

Interstitial Adipocytes in the Beagle Dog and New Zealand White Rabbit Choroid Plexus

Mini Review: The Last Mile—Opportunities and Challenges for Machine Learning in Digital Toxicologic Pathology

Tailored Pig Models for Preclinical Efficacy and Safety Testing of Targeted Therapies

Society of Toxicologic Pathology Digital Pathology and Image Analysis Special Interest Group Article: Opinion on the Application of Artificial Intelligence and Machine Learning to Digital Toxicologic Pathology

Duchenne and Becker Muscular Dystrophies: A Review of Animal Models, Clinical End Points, and Biomarker Quantification

Validation of a Muscle-Specific Tissue Image Analysis Tool for Quantitative Assessment of Dystrophin Staining in Frozen Muscle Biopsies

Proliferative and Nonproliferative Lesions of the Rat and Mouse Mammary, Zymbal’s, Preputial, and Clitoral Glands

Using Automated Image Analysis Algorithms to Distinguish Normal, Aberrant, and Degenerate Mitotic Figures Induced by Eg5 Inhibition

The Rat Mammary Gland: Morphologic Changes as an Indicator of Systemic Hormonal Perturbations Induced by Xenobiotics

Rat-Specific Decreases in Platelet Count Caused by a Humanized Monoclonal Antibody Against Sclerostin

Qualification of Cardiac Troponin I Concentration in Mouse Serum Using Isoproterenol and Implementation in Pharmacology Studies to Accelerate Drug Development

Developing a Qualification and Verification Strategy for Digital Tissue Image Analysis in Toxicological Pathology

A Selective Estrogen Receptor Modulator Designed for the Treatment of Uterine Leiomyoma with Unique Tissue Specificity for Uterus and Ovaries in Rats

A New Selective Estrogen Receptor Modulator with Potent Uterine Antagonist Activity, Agonist Activity in Bone, and Minimal Ovarian Stimulation

Modulation of allergic inflammation in mice deficient in TNF receptors

Androgen Dependent Mammary Gland Virilism in Rats Given the Selective Estrogen Receptor Modulator LY2066948 Hydrochloride

Using Deep Learning Artificial Intelligence Algorithms to Verify N-Nitroso-N-Methylurea and Urethane Positive Control Proliferative Changes in Tg-RasH2 Mouse Carcinogenicity Studies

Utilization of Genetically Altered Animals in the Pharmaceutical Industry

Proposal to Eliminate Urethane-Treated Positive Control Dose Groups in 26-Week Tg.rasH2 Carcinogenicity Studies

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