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Protein kinase D3 modulates MMP1 and MMP13 expression in human chondrocytes

PloS one, 2018-04, Vol.13 (4), p.e0195864

2018

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Leptin produced by joint white adipose tissue induces cartilage degradation via upregulation and activation of matrix metalloproteinases

Annals of the rheumatic diseases, 2012-03, Vol.71 (3), p.455-462

2012

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Leptin and Pro-Inflammatory Stimuli Synergistically Upregulate MMP-1 and MMP-3 Secretion in Human Gingival Fibroblasts

PloS one, 2016-02, Vol.11 (2), p.e0148024-e0148024

2016

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Macrophage migration and invasion is regulated by MMP10 expression

PloS one, 2013-05, Vol.8 (5), p.e63555

2013

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Proteinase-activated receptor 2 modulates OA-related pain, cartilage and bone pathology

Annals of the rheumatic diseases, 2016-11, Vol.75 (11), p.1989-1997

2016

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Systems biology reveals how altered TGFβ signalling with age reduces protection against pro-inflammatory stimuli

PLoS computational biology, 2019-01, Vol.15 (1), p.e1006685-e1006685

2019

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cAMP response element‐binding (CREB) recruitment following a specific CpG demethylation leads to the elevated expression of the matrix metalloproteinase 13 in human articular chondrocytes and osteoarthritis

The FASEB journal, 2012-07, Vol.26 (7), p.3000-3011

2012

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Novel Gain-of-Function Mutation in Stat1 Sumoylation Site Leads to CMC/CID Phenotype Responsive to Ruxolitinib

Journal of clinical immunology, 2019-11, Vol.39 (8), p.776-785

2019

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Tribbles and arthritis: what are the links?

Biochemical Society transactions, 2015-10, Vol.43 (5), p.1051

2015

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Cytokine-induced cysteine- serine-rich nuclear protein-1 (CSRNP1) selectively contributes to MMP1 expression in human chondrocytes

PloS one, 2018-11, Vol.13 (11), p.e0207240-e0207240

2018

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Activity of matrix metalloproteinase‐9 against native collagen types I and III

The FEBS journal, 2007-03, Vol.274 (5), p.1246-1255

2007

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The Mammalian Chitinase-like Lectin, YKL-40, Binds Specifically to Type I Collagen and Modulates the Rate of Type I Collagen Fibril Formation

The Journal of biological chemistry, 2006-07, Vol.281 (30), p.21082-21095

2006

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Glycogen Synthase Kinase 3 Inhibition Stimulates Human Cartilage Destruction and Exacerbates Murine Osteoarthritis

Arthritis & rheumatology (Hoboken, N.J.), 2014-08, Vol.66 (8), p.2175-2187

2014

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Oxidative changes and signalling pathways are pivotal in initiating age-related changes in articular cartilage

Annals of the rheumatic diseases, 2016-02, Vol.75 (2), p.449-458

2016

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Synergistic Collagenase Expression and Cartilage Collagenolysis Are Phosphatidylinositol 3-Kinase/Akt Signaling-dependent

The Journal of biological chemistry, 2008-05, Vol.283 (21), p.14221-14229

2008

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Cytokine-induced MMP13 Expression in Human Chondrocytes Is Dependent on Activating Transcription Factor 3 (ATF3) Regulation

The Journal of biological chemistry, 2017-02, Vol.292 (5), p.1625-1636

2017

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Matrix metalloproteinase‐13 is fully activated by neutrophil elastase and inactivates its serpin inhibitor, alpha‐1 antitrypsin: Implications for osteoarthritis

The FEBS journal, 2022-01, Vol.289 (1), p.121-139

2022

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Gain‐of‐function STAT1 mutations impair STAT3 activity in patients with chronic mucocutaneous candidiasis (CMC)

European journal of immunology, 2015-10, Vol.45 (10), p.2834-2846

2015

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Serine proteinases in the turnover of the cartilage extracellular matrix in the joint: implications for therapeutics

British journal of pharmacology, 2019-01, Vol.176 (1), p.38-51

2019

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Collagenase gene regulation by pro-inflammatory cytokines in cartilage

Frontiers in bioscience, 2007-01, Vol.12, p.536

2007

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Fibroblast activation protein alpha is expressed by chondrocytes following a pro-inflammatory stimulus and is elevated in osteoarthritis

Arthritis research & therapy, 2006-01, Vol.8 (1), p.R23-R23

2006

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Collagenolytic matrix metalloproteinases antagonize proteinase-activated receptor-2 activation, providing insights into extracellular matrix turnover

The Journal of biological chemistry, 2019-06, Vol.294 (26), p.10266-10277

2019

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Matriptase Induction of Metalloproteinase‐Dependent Aggrecanolysis In Vitro and In Vivo: Promotion of Osteoarthritic Cartilage Damage by Multiple Mechanisms

Arthritis & rheumatology (Hoboken, N.J.), 2017-08, Vol.69 (8), p.1601-1611

2017

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The serine proteinase hepsin is an activator of pro-matrix metalloproteinases: molecular mechanisms and implications for extracellular matrix turnover

Scientific reports, 2017-12, Vol.7 (1), p.16693-13, Article 16693

2017

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Protection against murine osteoarthritis by inhibition of the 26S proteasome and lysine-48 linked ubiquitination

Annals of the rheumatic diseases, 2015-08, Vol.74 (8), p.1580-1587

2015

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Protein kinase D3 modulates MMP1 and MMP13 expression in human chondrocytes

Leptin produced by joint white adipose tissue induces cartilage degradation via upregulation and activation of matrix metalloproteinases

Leptin and Pro-Inflammatory Stimuli Synergistically Upregulate MMP-1 and MMP-3 Secretion in Human Gingival Fibroblasts

Macrophage migration and invasion is regulated by MMP10 expression

Proteinase-activated receptor 2 modulates OA-related pain, cartilage and bone pathology

Systems biology reveals how altered TGFβ signalling with age reduces protection against pro-inflammatory stimuli

cAMP response element‐binding (CREB) recruitment following a specific CpG demethylation leads to the elevated expression of the matrix metalloproteinase 13 in human articular chondrocytes and osteoarthritis

Novel Gain-of-Function Mutation in Stat1 Sumoylation Site Leads to CMC/CID Phenotype Responsive to Ruxolitinib

Tribbles and arthritis: what are the links?

Cytokine-induced cysteine- serine-rich nuclear protein-1 (CSRNP1) selectively contributes to MMP1 expression in human chondrocytes

Activity of matrix metalloproteinase‐9 against native collagen types I and III

The Mammalian Chitinase-like Lectin, YKL-40, Binds Specifically to Type I Collagen and Modulates the Rate of Type I Collagen Fibril Formation

Glycogen Synthase Kinase 3 Inhibition Stimulates Human Cartilage Destruction and Exacerbates Murine Osteoarthritis

Oxidative changes and signalling pathways are pivotal in initiating age-related changes in articular cartilage

Synergistic Collagenase Expression and Cartilage Collagenolysis Are Phosphatidylinositol 3-Kinase/Akt Signaling-dependent

Cytokine-induced MMP13 Expression in Human Chondrocytes Is Dependent on Activating Transcription Factor 3 (ATF3) Regulation

Matrix metalloproteinase‐13 is fully activated by neutrophil elastase and inactivates its serpin inhibitor, alpha‐1 antitrypsin: Implications for osteoarthritis

Gain‐of‐function STAT1 mutations impair STAT3 activity in patients with chronic mucocutaneous candidiasis (CMC)

Serine proteinases in the turnover of the cartilage extracellular matrix in the joint: implications for therapeutics

Collagenase gene regulation by pro-inflammatory cytokines in cartilage

Fibroblast activation protein alpha is expressed by chondrocytes following a pro-inflammatory stimulus and is elevated in osteoarthritis

Collagenolytic matrix metalloproteinases antagonize proteinase-activated receptor-2 activation, providing insights into extracellular matrix turnover

Matriptase Induction of Metalloproteinase‐Dependent Aggrecanolysis In Vitro and In Vivo: Promotion of Osteoarthritic Cartilage Damage by Multiple Mechanisms

The serine proteinase hepsin is an activator of pro-matrix metalloproteinases: molecular mechanisms and implications for extracellular matrix turnover

Protection against murine osteoarthritis by inhibition of the 26S proteasome and lysine-48 linked ubiquitination

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