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Stability engineering of the human antibody repertoire

FEBS letters, 2014-01, Vol.588 (2), p.269-277

2014

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Efficient Intracellular Delivery of CRISPR-Cas Ribonucleoproteins through Receptor Mediated Endocytosis

ACS chemical biology, 2019-03, Vol.14 (3), p.554-561

2019

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CRISPR-Cpf1 mediates efficient homology-directed repair and temperature-controlled genome editing

Nature communications, 2017-12, Vol.8 (1), p.2024-9, Article 2024

2017

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General strategy for the generation of human antibody variable domains with increased aggregation resistance

Proceedings of the National Academy of Sciences - PNAS, 2012-07, Vol.109 (27), p.10879-10884

2012

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Redemption of autoantibodies on anergic B cells by variable-region glycosylation and mutation away from self-reactivity

Proceedings of the National Academy of Sciences - PNAS, 2014-06, Vol.111 (25), p.E2567-E2575

2014

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Receptor-Mediated Delivery of CRISPR-Cas9 Endonuclease for Cell-Type-Specific Gene Editing

Journal of the American Chemical Society, 2018-05, Vol.140 (21), p.6596-6603

2018

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Next-Generation Sequencing of Antibody Display Repertoires

Frontiers in immunology, 2018-02, Vol.9, p.118-118

2018

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Broadly neutralizing SARS-CoV-2 antibodies through epitope-based selection from convalescent patients

Nature communications, 2023-02, Vol.14 (1), p.687-13, Article 687

2023

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Long-term persistence of RBD+ memory B cells encoding neutralizing antibodies in SARS-CoV-2 infection

Cell reports. Medicine, 2021-04, Vol.2 (4), p.100228-100228, Article 100228

2021

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Potent SARS-CoV-2 binding and neutralization through maturation of iconic SARS-CoV-1 antibodies

mAbs, 2021-01, Vol.13 (1), p.1922134-1922134

2021

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Bispecific antibodies with native chain structure

Nature biotechnology, 2014-02, Vol.32 (2), p.136-137

2014

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Antibody-mediated delivery of CRISPR-Cas9 ribonucleoproteins in human cells

Protein engineering, design and selection, 2022-02, Vol.35

2022

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I-motif DNA structures are formed in the nuclei of human cells

Nature chemistry, 2018-06, Vol.10 (6), p.631-637

2018

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Fully Human VH Single Domains That Rival the Stability and Cleft Recognition of Camelid Antibodies

The Journal of biological chemistry, 2015-05, Vol.290 (19), p.11905-11917

2015

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Bispecific antibodies with native chain structure: two new methods overcome a major hurdle that blocked easy and efficient design and expression of human bispecific antibodies

Nature biotechnology, 2014-02, Vol.32 (2), p.136

2014

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Optimized CRISPR-Cpf1 system for genome editing in zebrafish

Methods (San Diego, Calif.), 2018-11, Vol.150, p.11-18

2018

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Immunizations with diverse sarbecovirus receptor-binding domains elicit SARS-CoV-2 neutralizing antibodies against a conserved site of vulnerability

Immunity (Cambridge, Mass.), 2021-12, Vol.54 (12), p.2908-2921.e6

2021

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Human genomic DNA is widely interspersed with i-motif structures

The EMBO journal, 2024-10, Vol.43 (20), p.4786-4804

2024

Volltextzugriff (PDF)

The retroelement Lx9 puts a brake on the immune response to virus infection

Nature (London), 2022-08, Vol.608 (7924), p.757-765

2022

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Human Antibody Bispecifics through Phage Display Selection

Biochemistry (Easton), 2019-04, Vol.58 (13), p.1701-1704

2019

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Tracking the clonal dynamics of SARS-CoV-2-specific T cells in children and adults with mild/asymptomatic COVID-19

Clinical immunology (Orlando, Fla.), 2023-01, Vol.246, p.109209, Article 109209

2023

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Expression of high-affinity human antibody fragments in bacteria

Nature protocols, 2012-02, Vol.7 (2), p.364-373

2012

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Rapid prediction of expression and refolding yields using phage display

Protein engineering, design and selection, 2013-10, Vol.26 (10), p.671-674

2013

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Structural basis for epitope masking and strain specificity of a conserved epitope in an intrinsically disordered malaria vaccine candidate

Scientific reports, 2015-05, Vol.5 (1), p.10103-10103, Article 10103

2015

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Stability engineering of the human antibody repertoire

Efficient Intracellular Delivery of CRISPR-Cas Ribonucleoproteins through Receptor Mediated Endocytosis

CRISPR-Cpf1 mediates efficient homology-directed repair and temperature-controlled genome editing

General strategy for the generation of human antibody variable domains with increased aggregation resistance

Redemption of autoantibodies on anergic B cells by variable-region glycosylation and mutation away from self-reactivity

Receptor-Mediated Delivery of CRISPR-Cas9 Endonuclease for Cell-Type-Specific Gene Editing

Next-Generation Sequencing of Antibody Display Repertoires

Broadly neutralizing SARS-CoV-2 antibodies through epitope-based selection from convalescent patients

Long-term persistence of RBD+ memory B cells encoding neutralizing antibodies in SARS-CoV-2 infection

High titre neutralizing antibodies in response to SARS-CoV-2 infection require RBD-specific CD4 T cells that include proliferative memory cells

Potent SARS-CoV-2 binding and neutralization through maturation of iconic SARS-CoV-1 antibodies

Bispecific antibodies with native chain structure

Antibody-mediated delivery of CRISPR-Cas9 ribonucleoproteins in human cells

I-motif DNA structures are formed in the nuclei of human cells

Fully Human VH Single Domains That Rival the Stability and Cleft Recognition of Camelid Antibodies

Bispecific antibodies with native chain structure: two new methods overcome a major hurdle that blocked easy and efficient design and expression of human bispecific antibodies

Optimized CRISPR-Cpf1 system for genome editing in zebrafish

Immunizations with diverse sarbecovirus receptor-binding domains elicit SARS-CoV-2 neutralizing antibodies against a conserved site of vulnerability

Human genomic DNA is widely interspersed with i-motif structures

The retroelement Lx9 puts a brake on the immune response to virus infection

Human Antibody Bispecifics through Phage Display Selection

Tracking the clonal dynamics of SARS-CoV-2-specific T cells in children and adults with mild/asymptomatic COVID-19

Expression of high-affinity human antibody fragments in bacteria

Rapid prediction of expression and refolding yields using phage display

Structural basis for epitope masking and strain specificity of a conserved epitope in an intrinsically disordered malaria vaccine candidate

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