UB Paderborn / Katalog / Suche / in CDI

Structure and function of a CE4 deacetylase isolated from a marine environment

PloS one, 2017-11, Vol.12 (11), p.e0187544-e0187544

2017

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Molecular Basis for the Inhibition of p53 by Mdmx

Cell cycle (Georgetown, Tex.), 2007-10, Vol.6 (19), p.2386-2392

2007

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Novel DYRK1A Inhibitor Rescues Learning and Memory Deficits in a Mouse Model of Down Syndrome

Pharmaceuticals (Basel, Switzerland), 2021-11, Vol.14 (11), p.1170

2021

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Shugoshin is a Mad1/Cdc20-like interactor of Mad2

The EMBO journal, 2011-07, Vol.30 (14), p.2868-2880

2011

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DYRK1A Kinase Inhibitors Promote β-Cell Survival and Insulin Homeostasis

Cells (Basel, Switzerland), 2021-08, Vol.10 (9), p.2263

2021

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Harmonin homology domain-mediated interaction of RTEL1 helicase with RPA and DNA provides insights into its recruitment to DNA repair sites

Nucleic acids research, 2024-02, Vol.52 (3), p.1450

2024

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Identification, functional characterization, assembly and structure of ToxIN type III toxin-antitoxin complex from E. coli

Nucleic acids research, 2022-02, Vol.50 (3), p.1687

2022

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2.09 Å Resolution structure of E. coli HigBA toxin-antitoxin complex reveals an ordered DNA-binding domain and intrinsic dynamics in antitoxin

Biochemical journal, 2020-10, Vol.477 (20), p.4001-4019

2020

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Probing the ATP-Binding Pocket of Protein Kinase DYRK1A with Benzothiazole Fragment Molecules

Journal of medicinal chemistry, 2016-11, Vol.59 (21), p.9814-9824

2016

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The structure of a dual-specificity tyrosine phosphorylation-regulated kinase 1A-PKC412 complex reveals disulfide-bridge formation with the anomalous catalytic loop HRD(HCD) cysteine

Acta crystallographica. Section D, Biological crystallography., 2015-05, Vol.71 (5), p.1207-1215

2015

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R2D ligase: Unveiling a novel DNA ligase with surprising DNA‐to‐RNA ligation activity

Biotechnology journal, 2024-03, Vol.19 (3), p.e2300711-n/a

2024

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Novel Scaffolds for Dual Specificity Tyrosine-Phosphorylation-Regulated Kinase (DYRK1A) Inhibitors

Journal of medicinal chemistry, 2018-09, Vol.61 (17), p.7560-7572

2018

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Luciferin and derivatives as a DYRK selective scaffold for the design of protein kinase inhibitors

European journal of medicinal chemistry, 2015-04, Vol.94, p.140-148

2015

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The crystal structure of the N‐acetylglucosamine 2‐epimerase from Nostoc sp. KVJ10 reveals the true dimer

Acta crystallographica. Section D, Biological crystallography., 2019-01, Vol.75 (1), p.90-100

2019

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Shugoshin is a Mad1/Cdc20‐like interactor of Mad2

The EMBO journal, 2011-07, Vol.30 (14), p.2868-2880

2011

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The crystal structure of haemoglobin from Atlantic cod

Acta crystallographica. Section F, Structural biology and crystallization communications, 2019-08, Vol.75 (8), p.537-542

2019

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NMR indicates that the small molecule RITA does not block p53-MDM2 binding in vitro

Nature medicine, 2005-11, Vol.11 (11), p.1135-1136

2005

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Assessing protein kinase target similarity: Comparing sequence, structure, and cheminformatics approaches

Biochimica et biophysica acta, 2015-10, Vol.1854 (10), p.1605-1616

2015

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An NMR-Based Antagonist Induced Dissociation Assay for Targeting the Ligand−Protein and Protein−Protein Interactions in Competition Binding Experiments

Journal of medicinal chemistry, 2007-09, Vol.50 (18), p.4382-4387

2007

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Enzyme-adenylate structure of a bacterial ATP-dependent DNA ligase with a minimized DNA-binding surface

Acta crystallographica. Section D, Biological crystallography., 2014-11, Vol.70 (11), p.3043-3056

2014

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Monitoring the Effects of Antagonists on Protein−Protein Interactions with NMR Spectroscopy

Journal of the American Chemical Society, 2005-09, Vol.127 (38), p.13220-13226

2005

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Shugoshin is a Mad1/Cdc20-like interactor of Mad2: Biochemically linking shugoshin to the spindle checkpoint

The EMBO journal, 2011-07, Vol.30 (14), p.2868-2880

2011

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p38α MAP Kinase Dimers with Swapped Activation Segments and a Novel Catalytic Loop Conformation

Journal of molecular biology, 2011-08, Vol.411 (2), p.474-485

2011

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Isoquinolin-1-one Inhibitors of the MDM2-p53 Interaction

ChemMedChem, 2008-07, Vol.3 (7), p.1118-1128

2008

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Structural origins of AGC protein kinase inhibitor selectivities: PKA as a drug discovery tool

Biological chemistry, 2012-10, Vol.393 (10), p.1121-1129

2012

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Structure and function of a CE4 deacetylase isolated from a marine environment

Molecular Basis for the Inhibition of p53 by Mdmx

Novel DYRK1A Inhibitor Rescues Learning and Memory Deficits in a Mouse Model of Down Syndrome

Shugoshin is a Mad1/Cdc20-like interactor of Mad2

DYRK1A Kinase Inhibitors Promote β-Cell Survival and Insulin Homeostasis

Harmonin homology domain-mediated interaction of RTEL1 helicase with RPA and DNA provides insights into its recruitment to DNA repair sites

Identification, functional characterization, assembly and structure of ToxIN type III toxin-antitoxin complex from E. coli

2.09 Å Resolution structure of E. coli HigBA toxin-antitoxin complex reveals an ordered DNA-binding domain and intrinsic dynamics in antitoxin

Probing the ATP-Binding Pocket of Protein Kinase DYRK1A with Benzothiazole Fragment Molecules

The structure of a dual-specificity tyrosine phosphorylation-regulated kinase 1A-PKC412 complex reveals disulfide-bridge formation with the anomalous catalytic loop HRD(HCD) cysteine

R2D ligase: Unveiling a novel DNA ligase with surprising DNA‐to‐RNA ligation activity

Novel Scaffolds for Dual Specificity Tyrosine-Phosphorylation-Regulated Kinase (DYRK1A) Inhibitors

Luciferin and derivatives as a DYRK selective scaffold for the design of protein kinase inhibitors

The crystal structure of the N‐acetylglucosamine 2‐epimerase from Nostoc sp. KVJ10 reveals the true dimer

Shugoshin is a Mad1/Cdc20‐like interactor of Mad2

The crystal structure of haemoglobin from Atlantic cod

NMR indicates that the small molecule RITA does not block p53-MDM2 binding in vitro

Assessing protein kinase target similarity: Comparing sequence, structure, and cheminformatics approaches

An NMR-Based Antagonist Induced Dissociation Assay for Targeting the Ligand−Protein and Protein−Protein Interactions in Competition Binding Experiments

Enzyme-adenylate structure of a bacterial ATP-dependent DNA ligase with a minimized DNA-binding surface

Monitoring the Effects of Antagonists on Protein−Protein Interactions with NMR Spectroscopy

Shugoshin is a Mad1/Cdc20-like interactor of Mad2: Biochemically linking shugoshin to the spindle checkpoint

p38α MAP Kinase Dimers with Swapped Activation Segments and a Novel Catalytic Loop Conformation

Isoquinolin-1-one Inhibitors of the MDM2-p53 Interaction

Structural origins of AGC protein kinase inhibitor selectivities: PKA as a drug discovery tool

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