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Pharmacokinetics and Pharmacodynamics of Canagliflozin, a Sodium Glucose Co-Transporter 2 Inhibitor, in Subjects With Type 2 Diabetes Mellitus

Journal of clinical pharmacology, 2013-06, Vol.53 (6), p.601-610

2013

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Mechanism of Increased LDL (Low-Density Lipoprotein) and Decreased Triglycerides With SGLT2 (Sodium-Glucose Cotransporter 2) Inhibition

Arteriosclerosis, thrombosis, and vascular biology, 2018-09, Vol.38 (9), p.2207

2018

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Pharmacokinetics of Aprepitant After Single and Multiple Oral Doses in Healthy Volunteers

Journal of clinical pharmacology, 2006-03, Vol.46 (3), p.291-300

2006

Volltextzugriff (PDF)

Expression of insulin receptor mRNA and insulin receptor substrate 1 in pancreatic islet beta-cells

Diabetes (New York, N.Y.), 1996-06, Vol.45 (6), p.711

1996

Volltextzugriff (PDF)

Glucose-induced insulin receptor tyrosine phosphorylation in insulin-secreting beta-cells

Diabetes (New York, N.Y.), 1995-07, Vol.44 (7), p.802

1995

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Insulin and secretagogues differentially regulate fluid-phase pinocytosis in insulin-secreting beta-cells

Biochemical journal, 1996-09, Vol.318 ( Pt 2) (2), p.623-629

1996

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Regulation of insulin receptor substrate-1 in liver and muscle of animal models of insulin resistance

The Journal of clinical investigation, 1992-11, Vol.90 (5), p.1839-1849

1992

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Purification and partial sequence analysis of pp185, the major cellular substrate of the insulin receptor tyrosine kinase

The Journal of biological chemistry, 1991-05, Vol.266 (13), p.8302-8311

1991

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The Insulin Receptor and Its Substrate: Molecular Determinants of Early Events in Insulin Action

Recent Progress in Hormone Research, 1993, Vol.48, p.291-339

1993

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Genistein differentially inhibits postreceptor effects of insulin in rat adipocytes without inhibiting the insulin receptor kinase

The Journal of biological chemistry, 1992-02, Vol.267 (6), p.3946-3951

1992

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Wortmannin inhibits insulin secretion in pancreatic islets and beta-TC3 cells independent of its inhibition of phosphatidylinositol 3-kinase

Diabetes (New York, N.Y.), 1996-07, Vol.45 (7), p.854

1996

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Insulin receptor signaling in the beta-cell influences insulin gene expression and insulin content: evidence for autocrine beta-cell regulation

Diabetes (New York, N.Y.), 1998-08, Vol.47 (8), p.1243

1998

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Increased protein kinase C activity is linked to reduced insulin receptor autophosphorylation in liver of starved rats

The Journal of biological chemistry, 1990-06, Vol.265 (18), p.10226-10231

1990

Volltextzugriff (PDF)

A Technique for Isolating Single Cells for Analysis by Reverse Transcription Polymerase Chain Reaction

Analytical biochemistry, 1995-09, Vol.230 (1), p.193-196

1995

Volltextzugriff (PDF)

Infected acute myocardial infarct with rupture in systemic lupus erythematosus

The American journal of cardiology, 1987-02, Vol.59 (5), p.488-489

1987

Volltextzugriff (PDF)

Phase III, Randomized Study of Gemcitabine and Oxaliplatin Versus Gemcitabine (fixed-dose rate infusion) Compared With Gemcitabine (30-minute infusion) in Patients With Pancreatic Carcinoma E6201: A Trial of the Eastern Cooperative Oncology Group

Journal of clinical oncology, 2009-08, Vol.27 (23), p.3778-3785

2009

Volltextzugriff (PDF)

T cell-intrinsic ASC critically promotes T(H)17-mediated experimental autoimmune encephalomyelitis

Nature immunology, 2016-05, Vol.17 (5), p.583

2016

Volltextzugriff (PDF)

Phase I Study of Intravenous Vascular Endothelial Growth Factor Trap, Aflibercept, in Patients With Advanced Solid Tumors

Journal of clinical oncology, 2010-01, Vol.28 (2), p.207-214

2010

Volltextzugriff (PDF)

Treatment of Patients with the Hypereosinophilic Syndrome with Mepolizumab

The New England journal of medicine, 2008-03, Vol.358 (12), p.1215-1228

2008

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A novel class of TMPRSS2 inhibitors potently block SARS-CoV-2 and MERS-CoV viral entry and protect human epithelial lung cells

Proceedings of the National Academy of Sciences - PNAS, 2021-10, Vol.118 (43)

2021

Volltextzugriff (PDF)

Transcatheter Aortic-Valve Replacement with a Balloon-Expandable Valve in Low-Risk Patients

The New England journal of medicine, 2019-05, Vol.380 (18), p.1695-1705

2019

Volltextzugriff (PDF)

The E3 ubiquitin ligase midline 1 promotes allergen and rhinovirus-induced asthma by inhibiting protein phosphatase 2A activity

Nature medicine, 2013-02, Vol.19 (2), p.232-237

2013

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Pharmacokinetics and Pharmacodynamics of Canagliflozin, a Sodium Glucose Co-Transporter 2 Inhibitor, in Subjects With Type 2 Diabetes Mellitus

Mechanism of Increased LDL (Low-Density Lipoprotein) and Decreased Triglycerides With SGLT2 (Sodium-Glucose Cotransporter 2) Inhibition

Pharmacokinetics of Aprepitant After Single and Multiple Oral Doses in Healthy Volunteers

Expression of insulin receptor mRNA and insulin receptor substrate 1 in pancreatic islet beta-cells

Glucose-induced insulin receptor tyrosine phosphorylation in insulin-secreting beta-cells

Insulin and secretagogues differentially regulate fluid-phase pinocytosis in insulin-secreting beta-cells

Regulation of insulin receptor substrate-1 in liver and muscle of animal models of insulin resistance

Purification and partial sequence analysis of pp185, the major cellular substrate of the insulin receptor tyrosine kinase

The Insulin Receptor and Its Substrate: Molecular Determinants of Early Events in Insulin Action

Genistein differentially inhibits postreceptor effects of insulin in rat adipocytes without inhibiting the insulin receptor kinase

Wortmannin inhibits insulin secretion in pancreatic islets and beta-TC3 cells independent of its inhibition of phosphatidylinositol 3-kinase

Insulin receptor signaling in the beta-cell influences insulin gene expression and insulin content: evidence for autocrine beta-cell regulation

Increased protein kinase C activity is linked to reduced insulin receptor autophosphorylation in liver of starved rats

A Technique for Isolating Single Cells for Analysis by Reverse Transcription Polymerase Chain Reaction

Infected acute myocardial infarct with rupture in systemic lupus erythematosus

A Next-Generation TRK Kinase Inhibitor Overcomes Acquired Resistance to Prior TRK Kinase Inhibition in Patients with TRK Fusion-Positive Solid Tumors

Phase III, Randomized Study of Gemcitabine and Oxaliplatin Versus Gemcitabine (fixed-dose rate infusion) Compared With Gemcitabine (30-minute infusion) in Patients With Pancreatic Carcinoma E6201: A Trial of the Eastern Cooperative Oncology Group

Liver microRNA-21 is overexpressed in non-alcoholic steatohepatitis and contributes to the disease in experimental models by inhibiting PPARα expression

T cell-intrinsic ASC critically promotes T(H)17-mediated experimental autoimmune encephalomyelitis

Phase I Study of Intravenous Vascular Endothelial Growth Factor Trap, Aflibercept, in Patients With Advanced Solid Tumors

Treatment of Patients with the Hypereosinophilic Syndrome with Mepolizumab

A novel class of TMPRSS2 inhibitors potently block SARS-CoV-2 and MERS-CoV viral entry and protect human epithelial lung cells

Transcatheter Aortic-Valve Replacement with a Balloon-Expandable Valve in Low-Risk Patients

Single cell transcriptomic analysis of HPV16-infected epithelium identifies a keratinocyte subpopulation implicated in cancer

The E3 ubiquitin ligase midline 1 promotes allergen and rhinovirus-induced asthma by inhibiting protein phosphatase 2A activity

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