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PRAS40 Regulates mTORC1 Kinase Activity by Functioning as a Direct Inhibitor of Substrate Binding

The Journal of biological chemistry, 2007-07, Vol.282 (27), p.20036-20044

2007

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Inhibition of mTOR Activity Restores Tamoxifen Response in Breast Cancer Cells with Aberrant Akt Activity

Clinical cancer research, 2004-12, Vol.10 (23), p.8059-8067

2004

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Mechanism of Akt1 inhibition of breast cancer cell invasion reveals a protumorigenic role for TSC2

Proceedings of the National Academy of Sciences - PNAS, 2006-03, Vol.103 (11), p.4134-4139

2006

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Identification of a Proline-rich Akt Substrate as a 14-3-3 Binding Partner

The Journal of biological chemistry, 2003-03, Vol.278 (12), p.10189-10194

2003

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Inorganic Polyphosphate Stimulates Mammalian TOR, a Kinase Involved in the Proliferation of Mammary Cancer Cells

Proceedings of the National Academy of Sciences - PNAS, 2003-09, Vol.100 (20), p.11249-11254

2003

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Protein kinase B/Akt phosphorylation of PDE3A and its role in mammalian oocyte maturation

The EMBO journal, 2006-12, Vol.25 (24), p.5716-5725

2006

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Modulation of Insulin-stimulated Degradation of Human Insulin Receptor Substrate-1 by Serine 312 Phosphorylation

The Journal of biological chemistry, 2003-03, Vol.278 (10), p.8199-8211

2003

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Insulin-stimulated Akt kinase activity is reduced in skeletal muscle from NIDDM subjects

Diabetes (New York, N.Y.), 1998-08, Vol.47 (8), p.1281

1998

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Protein Kinase C Modulation of Insulin Receptor Substrate-1 Tyrosine Phosphorylation Requires Serine 612

Biochemistry (Easton), 1997-10, Vol.36 (42), p.12939-12947

1997

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Expression of Constitutively Active Akt-3 in MCF-7 Breast Cancer Cells Reverses the Estrogen and Tamoxifen Responsivity of these Cells in Vivo

Clinical cancer research, 2003-08, Vol.9 (8), p.2933-2939

2003

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Akt promotes increased mammalian cell size by stimulating protein synthesis and inhibiting protein degradation

American journal of physiology: endocrinology and metabolism, 2003-11, Vol.285 (5), p.E964-E972

2003

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Juxtamembrane tyrosine residues couple the Eph family receptor EphB2/Nuk to specific SH2 domain proteins in neuronal cells

The EMBO journal, 1997-07, Vol.16 (13), p.3877-3888

1997

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Divergent effects of exercise on metabolic and mitogenic signaling pathways in human skeletal muscle

The FASEB journal, 1998-10, Vol.12 (13), p.1379-1389

1998

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On the Mechanism for Neomycin Reversal of Wortmannin Inhibition of Insulin Stimulation of Glucose Uptake

The Journal of biological chemistry, 2004-12, Vol.279 (53), p.55277-55282

2004

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A comparative study of the efficacy of intervention strategies on student electricity use in campus residence halls

International journal of sustainability in higher education, 2017-01, Vol.18 (4), p.503-519

2017

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Improved glucose tolerance restores insulin-stimulated Akt kinase activity and glucose transport in skeletal muscle from diabetic Goto-Kakizaki rats

Diabetes (New York, N.Y.), 1997-12, Vol.46 (12), p.2110

1997

Volltextzugriff (PDF)

Reduced Hippocampal Insulin-Degrading Enzyme in Late-Onset Alzheimer's Disease Is Associated with the Apolipoprotein E-ε4 Allele

The American journal of pathology, 2003, Vol.162 (1), p.313-319

2003

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Stimulation of Lipolysis and Hormone-sensitive Lipase via the Extracellular Signal-regulated Kinase Pathway

The Journal of biological chemistry, 2001-11, Vol.276 (48), p.45456-45461

2001

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Up-regulation of Akt3 in Estrogen Receptor-deficient Breast Cancers and Androgen-independent Prostate Cancer Lines

The Journal of biological chemistry, 1999-07, Vol.274 (31), p.21528-21532

1999

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Expression of a Constitutively Active Akt Ser/Thr Kinase in 3T3-L1 Adipocytes Stimulates Glucose Uptake and Glucose Transporter 4 Translocation

The Journal of biological chemistry, 1996-12, Vol.271 (49), p.31372-31378

1996

Volltextzugriff (PDF)

Modulation of Insulin Receptor Substrate-1 Tyrosine Phosphorylation and Function by Mitogen-activated Protein Kinase

The Journal of biological chemistry, 1997-12, Vol.272 (50), p.31400-31406

1997

Volltextzugriff (PDF)

Evidence of Insulin-Stimulated Phosphorylation and Activation of the Mammalian Target of Rapamycin Mediated by a Protein Kinase B Signaling Pathway

Proceedings of the National Academy of Sciences - PNAS, 1998-06, Vol.95 (13), p.7772-7777

1998

Volltextzugriff (PDF)

Akt, a Pleckstrin Homology Domain Containing Kinase, Is Activated Primarily by Phosphorylation

The Journal of biological chemistry, 1996-09, Vol.271 (36), p.21920-21926

1996

Volltextzugriff (PDF)

Structure of the Receptor for Insulin-Like Growth Factor II: The Puzzle Amplified

Science (American Association for the Advancement of Science), 1988-03, Vol.239 (4845), p.1269-1271

Roth, Richard A.

1988

Volltextzugriff (PDF)

Insulin-like growth factor II receptor as a multifunctional binding protein

Nature (London), 1987-09, Vol.329 (6137), p.301-307

1987

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PRAS40 Regulates mTORC1 Kinase Activity by Functioning as a Direct Inhibitor of Substrate Binding

Inhibition of mTOR Activity Restores Tamoxifen Response in Breast Cancer Cells with Aberrant Akt Activity

Mechanism of Akt1 inhibition of breast cancer cell invasion reveals a protumorigenic role for TSC2

Identification of a Proline-rich Akt Substrate as a 14-3-3 Binding Partner

Inorganic Polyphosphate Stimulates Mammalian TOR, a Kinase Involved in the Proliferation of Mammary Cancer Cells

Protein kinase B/Akt phosphorylation of PDE3A and its role in mammalian oocyte maturation

Modulation of Insulin-stimulated Degradation of Human Insulin Receptor Substrate-1 by Serine 312 Phosphorylation

Insulin-stimulated Akt kinase activity is reduced in skeletal muscle from NIDDM subjects

Protein Kinase C Modulation of Insulin Receptor Substrate-1 Tyrosine Phosphorylation Requires Serine 612

Expression of Constitutively Active Akt-3 in MCF-7 Breast Cancer Cells Reverses the Estrogen and Tamoxifen Responsivity of these Cells in Vivo

Akt promotes increased mammalian cell size by stimulating protein synthesis and inhibiting protein degradation

Juxtamembrane tyrosine residues couple the Eph family receptor EphB2/Nuk to specific SH2 domain proteins in neuronal cells

Divergent effects of exercise on metabolic and mitogenic signaling pathways in human skeletal muscle

On the Mechanism for Neomycin Reversal of Wortmannin Inhibition of Insulin Stimulation of Glucose Uptake

A comparative study of the efficacy of intervention strategies on student electricity use in campus residence halls

Improved glucose tolerance restores insulin-stimulated Akt kinase activity and glucose transport in skeletal muscle from diabetic Goto-Kakizaki rats

Reduced Hippocampal Insulin-Degrading Enzyme in Late-Onset Alzheimer's Disease Is Associated with the Apolipoprotein E-ε4 Allele

Stimulation of Lipolysis and Hormone-sensitive Lipase via the Extracellular Signal-regulated Kinase Pathway

Up-regulation of Akt3 in Estrogen Receptor-deficient Breast Cancers and Androgen-independent Prostate Cancer Lines

Expression of a Constitutively Active Akt Ser/Thr Kinase in 3T3-L1 Adipocytes Stimulates Glucose Uptake and Glucose Transporter 4 Translocation

Modulation of Insulin Receptor Substrate-1 Tyrosine Phosphorylation and Function by Mitogen-activated Protein Kinase

Evidence of Insulin-Stimulated Phosphorylation and Activation of the Mammalian Target of Rapamycin Mediated by a Protein Kinase B Signaling Pathway

Akt, a Pleckstrin Homology Domain Containing Kinase, Is Activated Primarily by Phosphorylation

Structure of the Receptor for Insulin-Like Growth Factor II: The Puzzle Amplified

Insulin-like growth factor II receptor as a multifunctional binding protein

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