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Botulinum Neurotoxins: Biology, Pharmacology, and Toxicology

Pharmacological reviews, 2017-04, Vol.69 (2), p.200-235

2017

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Toxicology and pharmacology of botulinum and tetanus neurotoxins: an update

Archives of toxicology, 2022-06, Vol.96 (6), p.1521-1539

2022

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Long-Distance Retrograde Effects of Botulinum Neurotoxin A

The Journal of neuroscience, 2008-04, Vol.28 (14), p.3689-3696

2008

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Clinical duration of action of different botulinum toxin types in humans

Toxicon (Oxford), 2020-05, Vol.179, p.84-91

2020

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Evidence for anterograde transport and transcytosis of botulinum neurotoxin A (BoNT/A)

The Journal of neuroscience, 2011-11, Vol.31 (44), p.15650-15659

2011

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Botulinum neurotoxins A and E undergo retrograde axonal transport in primary motor neurons

PLoS pathogens, 2012-12, Vol.8 (12), p.e1003087

2012

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On the translocation of botulinum and tetanus neurotoxins across the membrane of acidic intracellular compartments

Biochimica et biophysica acta, 2016-03, Vol.1858 (3), p.467-474

2016

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Hsp90 and Thioredoxin-Thioredoxin Reductase enable the catalytic activity of Clostridial neurotoxins inside nerve terminals

Toxicon (Oxford), 2018-06, Vol.147, p.32-37

2018

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Detection of VAMP Proteolysis by Tetanus and Botulinum Neurotoxin Type B In Vivo with a Cleavage-Specific Antibody

International journal of molecular sciences, 2022-04, Vol.23 (8), p.4355

2022

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Botulinum neurotoxin C mutants reveal different effects of syntaxin or SNAP-25 proteolysis on neuromuscular transmission

PLoS pathogens, 2017-08, Vol.13 (8), p.e1006567

2017

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Latrotoxin-Induced Neuromuscular Junction Degeneration Reveals Urocortin 2 as a Critical Contributor to Motor Axon Terminal Regeneration

International journal of molecular sciences, 2022-01, Vol.23 (3), p.1186

2022

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Thioredoxin and Its Reductase Are Present on Synaptic Vesicles, and Their Inhibition Prevents the Paralysis Induced by Botulinum Neurotoxins

Cell reports (Cambridge), 2014-09, Vol.8 (6), p.1870-1878

2014

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Tables of Toxicity of Botulinum and Tetanus Neurotoxins

Toxins, 2019-11, Vol.11 (12), p.686

2019

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Novel Small Molecule Inhibitors That Prevent the Neuroparalysis of Tetanus Neurotoxin

Pharmaceuticals (Basel, Switzerland), 2021-11, Vol.14 (11), p.1134

2021

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Tetanus neurotoxin-induced epilepsy in mouse visual cortex

Epilepsia (Copenhagen), 2012-07, Vol.53 (7), p.e132-e136

2012

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Botulinum neurotoxins: genetic, structural and mechanistic insights

Nature reviews. Microbiology, 2014-08, Vol.12 (8), p.535-549

2014

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High Conservation of Tetanus and Botulinum Neurotoxins Cleavage Sites on Human SNARE Proteins Suggests That These Pathogens Exerted Little or No Evolutionary Pressure on Humans

Toxins, 2017-12, Vol.9 (12), p.404

2017

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Botulinum Neurotoxins: Biology, Pharmacology, and Toxicology

Pharmacological reviews, 2017-04, Vol.69 (2), p.200-235

2017

Volltextzugriff (PDF)

Altered sensory processing and dendritic remodeling in hyperexcitable visual cortical networks

Brain structure & function, 2016-07, Vol.221 (6), p.2919-2936

2016

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Equivalent Effects of Snake PLA2 Neurotoxins and Lysophospholipid-Fatty Acid Mixtures

Science (American Association for the Advancement of Science), 2005-12, Vol.310 (5754), p.1678-1680

2005

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Evidence for a radial SNARE super-complex mediating neurotransmitter release at the Drosophila neuromuscular junction

Journal of cell science, 2013-07, Vol.126 (Pt 14), p.3134-3140

2013

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A Novel Inhibitor Prevents the Peripheral Neuroparalysis of Botulinum Neurotoxins

Scientific reports, 2015-12, Vol.5 (1), p.17513, Article 17513

2015

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The thioredoxin reductase – Thioredoxin redox system cleaves the interchain disulphide bond of botulinum neurotoxins on the cytosolic surface of synaptic vesicles

Toxicon (Oxford), 2015-12, Vol.107 (Pt A), p.32-36

2015

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Entering neurons: botulinum toxins and synaptic vesicle recycling

EMBO reports, 2006-10, Vol.7 (10), p.995-999

2006

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SNAP-25 Modulation of Calcium Dynamics Underlies Differences in GABAergic and Glutamatergic Responsiveness to Depolarization

Neuron (Cambridge, Mass.), 2004-02, Vol.41 (4), p.599-610

2004

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Botulinum Neurotoxins: Biology, Pharmacology, and Toxicology

Toxicology and pharmacology of botulinum and tetanus neurotoxins: an update

Long-Distance Retrograde Effects of Botulinum Neurotoxin A

Clinical duration of action of different botulinum toxin types in humans

Evidence for anterograde transport and transcytosis of botulinum neurotoxin A (BoNT/A)

Botulinum neurotoxins A and E undergo retrograde axonal transport in primary motor neurons

On the translocation of botulinum and tetanus neurotoxins across the membrane of acidic intracellular compartments

Hsp90 and Thioredoxin-Thioredoxin Reductase enable the catalytic activity of Clostridial neurotoxins inside nerve terminals

Detection of VAMP Proteolysis by Tetanus and Botulinum Neurotoxin Type B In Vivo with a Cleavage-Specific Antibody

Botulinum neurotoxin C mutants reveal different effects of syntaxin or SNAP-25 proteolysis on neuromuscular transmission

Latrotoxin-Induced Neuromuscular Junction Degeneration Reveals Urocortin 2 as a Critical Contributor to Motor Axon Terminal Regeneration

Thioredoxin and Its Reductase Are Present on Synaptic Vesicles, and Their Inhibition Prevents the Paralysis Induced by Botulinum Neurotoxins

Tables of Toxicity of Botulinum and Tetanus Neurotoxins

Novel Small Molecule Inhibitors That Prevent the Neuroparalysis of Tetanus Neurotoxin

Tetanus neurotoxin-induced epilepsy in mouse visual cortex

Botulinum neurotoxins: genetic, structural and mechanistic insights

High Conservation of Tetanus and Botulinum Neurotoxins Cleavage Sites on Human SNARE Proteins Suggests That These Pathogens Exerted Little or No Evolutionary Pressure on Humans

Botulinum Neurotoxins: Biology, Pharmacology, and Toxicology

Altered sensory processing and dendritic remodeling in hyperexcitable visual cortical networks

Equivalent Effects of Snake PLA2 Neurotoxins and Lysophospholipid-Fatty Acid Mixtures

Evidence for a radial SNARE super-complex mediating neurotransmitter release at the Drosophila neuromuscular junction

A Novel Inhibitor Prevents the Peripheral Neuroparalysis of Botulinum Neurotoxins

The thioredoxin reductase – Thioredoxin redox system cleaves the interchain disulphide bond of botulinum neurotoxins on the cytosolic surface of synaptic vesicles

Entering neurons: botulinum toxins and synaptic vesicle recycling

SNAP-25 Modulation of Calcium Dynamics Underlies Differences in GABAergic and Glutamatergic Responsiveness to Depolarization

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