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Design, Synthesis, and Structure−Activity Relationships of Novel 2-Substituted Pyrazinoylguanidine Epithelial Sodium Channel Blockers: Drugs for Cystic Fibrosis and Chronic Bronchitis

Journal of medicinal chemistry, 2006-07, Vol.49 (14), p.4098-4115

2006

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Airway drug pharmacokinetics via analysis of exhaled breath condensate

Pulmonary pharmacology & therapeutics, 2014-02, Vol.27 (1), p.76-82

2014

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Effect of topically applied epithelial sodium channel inhibitors on tear production in normal mice and in mice with induced aqueous tear deficiency

Journal of ocular pharmacology and therapeutics, 2012-08, Vol.28 (4), p.433-438

2012

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Acute hyperkalemia associated with inhalation of a potent ENaC antagonist: Phase 1 trial of GS-9411

Journal of aerosol medicine and pulmonary drug delivery, 2014-06, Vol.27 (3), p.200-208

2014

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Pharmacological properties of N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N'-4-[4-(2,3-dihydroxypropoxy)phenyl]butyl-guanidine methanesulfonate (552-02), a novel epithelial sodium channel blocker with potential clinical efficacy for cystic fibrosis lung disease

The Journal of pharmacology and experimental therapeutics, 2008-04, Vol.325 (1), p.77-88

2008

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The novel long acting ENaC blocker P643 has therapeutic effects in chronic cystic fibrosis-like lung disease in mice

Journal of cystic fibrosis, 2009, Vol.8, p.S26-S26

2009

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Potent suppression of HIV-1 replication in humans by T-20, a peptide inhibitor of gp41-mediated virus entry

Nature medicine, 1998-11, Vol.4 (11), p.1302-1307

1998

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Christianity in South and Central Asia

1, 2019

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Convergent catalytic asymmetric synthesis of camptothecin analog GI147211C

Tetrahedron, 1997-08, Vol.53 (32), p.10953-10970

1997

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A short, enantioselective synthesis of the carbocyclic nucleoside carbovir

Journal of organic chemistry, 1991-08, Vol.56 (16), p.4990-4993

1991

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Characterization and localization of cannabinoid receptors in rat brain: a quantitative in vitro autoradiographic study

The Journal of neuroscience, 1991-02, Vol.11 (2), p.563-583

1991

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Cannabinoid Receptor Localization in Brain

Proceedings of the National Academy of Sciences - PNAS, 1990-03, Vol.87 (5), p.1932-1936

1990

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Christianity in Oceania

1, 2021

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The cannabinoid receptor: biochemical, anatomical and behavioral characterization

Trends in Neurosciences, 1990-10, Vol.13 (10), p.420-423

1990

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Behavioral, biochemical, and molecular modeling evaluations of cannabinoid analogs

Pharmacology Biochemistry and Behavior [PHARMACOL., BIOCHEM. BEHAV.]. Vol. 40, no. 3. 1991, 1991-11, Vol.40 (3), p.471-478

1991

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Large-Area Remote Sensing Coverage of Archaeological Sites with a Dual-Track Cart-Mounted Cesium Magnetometer

Journal of field archaeology, 2007-01, Vol.32 (2), p.133-148

2007

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Cannabinoid receptor binding and agonist activity of amides and esters of arachidonic acid

Molecular pharmacology, 1994-09, Vol.46 (3), p.516-522

1994

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Structure-activity relationships for cannabinoid receptor-binding and analgesic activity: studies of bicyclic cannabinoid analogs

Molecular pharmacology, 1993-11, Vol.44 (5), p.1008-1015

1993

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Design, synthesis, and pharmacological evaluation of ultrashort- to long-acting opioid analgetics

Journal of medicinal chemistry, 1991-07, Vol.34 (7), p.2202-2208

1991

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Design, synthesis, and pharmacological evaluation of ultrashort- to long-acting opioid analgesics

Journal of medicinal chemistry, 1991-07, Vol.34 (7), p.2202-2208

1991

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Ca(2+)-dependent release from rat brain of cannabinoid receptor binding activity

Journal of neurochemistry, 1992-02, Vol.58 (2), p.780-782

1992

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(Aminoalkyl)indole Isothiocyanates as Potential Electrophilic Affinity Ligands for the Brain Cannabinoid Receptor

Journal of medicinal chemistry, 1996-05, Vol.39 (10), p.1967-1974

1996

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Ca2+ ‐Dependent Release from Rat Brain of Cannabinoid Receptor Binding Activity

Journal of neurochemistry, 1992-02, Vol.58 (2), p.780-782

1992

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Substituted dihydrobenzopyran and dihydrobenzofuran thiazolidine-2,4-diones as hypoglycemic agents

Journal of medicinal chemistry, 1991-01, Vol.34 (1), p.319-325

1991

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Ca 2+ ‐Dependent Release from Rat Brain of Cannabinoid Receptor Binding Activity

Journal of neurochemistry, 1992-02, Vol.58 (2), p.780-782

1992

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Design, Synthesis, and Structure−Activity Relationships of Novel 2-Substituted Pyrazinoylguanidine Epithelial Sodium Channel Blockers: Drugs for Cystic Fibrosis and Chronic Bronchitis

Airway drug pharmacokinetics via analysis of exhaled breath condensate

Effect of topically applied epithelial sodium channel inhibitors on tear production in normal mice and in mice with induced aqueous tear deficiency

Acute hyperkalemia associated with inhalation of a potent ENaC antagonist: Phase 1 trial of GS-9411

Pharmacological properties of N-(3,5-diamino-6-chloropyrazine-2-carbonyl)-N'-4-[4-(2,3-dihydroxypropoxy)phenyl]butyl-guanidine methanesulfonate (552-02), a novel epithelial sodium channel blocker with potential clinical efficacy for cystic fibrosis lung disease

The novel long acting ENaC blocker P643 has therapeutic effects in chronic cystic fibrosis-like lung disease in mice

Potent suppression of HIV-1 replication in humans by T-20, a peptide inhibitor of gp41-mediated virus entry

Christianity in South and Central Asia

Convergent catalytic asymmetric synthesis of camptothecin analog GI147211C

A short, enantioselective synthesis of the carbocyclic nucleoside carbovir

Characterization and localization of cannabinoid receptors in rat brain: a quantitative in vitro autoradiographic study

Cannabinoid Receptor Localization in Brain

Christianity in Oceania

The cannabinoid receptor: biochemical, anatomical and behavioral characterization

Behavioral, biochemical, and molecular modeling evaluations of cannabinoid analogs

Large-Area Remote Sensing Coverage of Archaeological Sites with a Dual-Track Cart-Mounted Cesium Magnetometer

Cannabinoid receptor binding and agonist activity of amides and esters of arachidonic acid

Structure-activity relationships for cannabinoid receptor-binding and analgesic activity: studies of bicyclic cannabinoid analogs

Design, synthesis, and pharmacological evaluation of ultrashort- to long-acting opioid analgetics

Design, synthesis, and pharmacological evaluation of ultrashort- to long-acting opioid analgesics

Ca(2+)-dependent release from rat brain of cannabinoid receptor binding activity

(Aminoalkyl)indole Isothiocyanates as Potential Electrophilic Affinity Ligands for the Brain Cannabinoid Receptor

Ca2+ ‐Dependent Release from Rat Brain of Cannabinoid Receptor Binding Activity

Substituted dihydrobenzopyran and dihydrobenzofuran thiazolidine-2,4-diones as hypoglycemic agents

Ca 2+ ‐Dependent Release from Rat Brain of Cannabinoid Receptor Binding Activity

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