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Risk prediction of prevalent diabetes in a Swiss population using a weighted genetic score--the CoLaus Study

Diabetologia, 2009-04, Vol.52 (4), p.600-608

2009

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Polyallelic structural variants can provide accurate, highly informative genetic markers focused on diagnosis and therapeutic targets: Accuracy vs. Precision

Clinical pharmacology and therapeutics, 2016-02, Vol.99 (2), p.169-171

Roses, AD

2016

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Genome-wide association study of recurrent major depressive disorder in two European case-control cohorts

Molecular psychiatry, 2010-06, Vol.15 (6), p.589-601

2010

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A genome-wide association study implicates the APOE locus in nonpathological cognitive ageing

Molecular psychiatry, 2014-01, Vol.19 (1), p.76-87

2014

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Using Genetics to Enable Studies on the Prevention of Alzheimer's Disease

Clinical pharmacology and therapeutics, 2013-02, Vol.93 (2), p.177-185

2013

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Efficacy of rosiglitazone in a genetically defined population with mild-to-moderate Alzheimer's disease

The pharmacogenomics journal, 2006-07, Vol.6 (4), p.246-254

2006

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Pharmacogenetics and future drug development and delivery

The Lancet (British edition), 2000-04, Vol.355 (9212), p.1358-1361

Roses, Allen D

2000

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Pharmacogenetics of hypersensitivity to abacavir: from PGx hypothesis to confirmation to clinical utility

The pharmacogenomics journal, 2008-12, Vol.8 (6), p.365-374

2008

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Complex disease-associated pharmacogenetics: drug efficacy, drug safety, and confirmation of a pathogenetic hypothesis (Alzheimer's disease)

The pharmacogenomics journal, 2007-02, Vol.7 (1), p.10-28

2007

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Gene Dose of Apolipoprotein E Type 4 Allele and the Risk of Alzheimer's Disease in Late Onset Families

Science (American Association for the Advancement of Science), 1993-08, Vol.261 (5123), p.921-923

1993

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Increased Amyloid β-Peptide Deposition in Cerebral Cortex as a Consequence of Apolipoprotein E Genotype in Late-Onset Alzheimer Disease

Proceedings of the National Academy of Sciences - PNAS, 1993-10, Vol.90 (20), p.9649-9653

1993

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Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

Nature (London), 1995-06, Vol.375 (6534), p.754-760

1995

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Stimulation of Cholecystokinin-A Receptors With Gl181771X: A Failed Clinical Trial That Did Not Test the Pharmacogenetic Hypothesis for Reduction of Food Intake

Clinical pharmacology and therapeutics, 2009-04, Vol.85 (4), p.362-365

Roses, AD

2009

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Apolipoprotein E Affects the Rate of Alzheimer Disease Expression: (β-Amyloid Burden Is a Secondary Consequence Dependent on APOE Genotype and Duration of Disease

Journal of neuropathology and experimental neurology, 1994-09, Vol.53 (5), p.429-437

Roses, Allen D

1994

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APOLIPOPROTEIN E ALLELES AS RISK FACTORS IN ALZHEIMER'S DISEASE

Annual review of medicine, 1996-01, Vol.47 (1), p.387-400

Roses, M.D, Allen D

1996

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Apolipoprotein E: High-Avidity Binding to β-Amyloid and Increased Frequency of Type 4 Allele in Late-Onset Familial Alzheimer Disease

Proceedings of the National Academy of Sciences - PNAS, 1993-03, Vol.90 (5), p.1977-1981

1993

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Pharmacogenetics

Human molecular genetics, 2001-10, Vol.10 (20), p.2261-2267

ROSES, Allen D

2001

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Binding of Human Apolipoprotein E to Synthetic Amyloid β Peptide: Isoform-Specific Effects and Implications for Late-Onset Alzheimer Disease

Proceedings of the National Academy of Sciences - PNAS, 1993-09, Vol.90 (17), p.8098-8102

1993

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Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease

Nature genetics, 1994-06, Vol.7 (2), p.180-184

1994

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SNPing Away at Complex Diseases: Analysis of Single-Nucleotide Polymorphisms around APOE in Alzheimer Disease

American journal of human genetics, 2000-08, Vol.67 (2), p.383-394

2000

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A TOMM40 variable-length polymorphism predicts the age of late-onset Alzheimer's disease

The pharmacogenomics journal, 2010-10, Vol.10 (5), p.375-384

2010

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Apolipoprotein E and Alzheimer's disease

Annual review of neuroscience, 1996-01, Vol.19 (1), p.53-77

1996

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Apolipoprotein E and Alzheimer Disease

Proceedings of the National Academy of Sciences - PNAS, 1995-05, Vol.92 (11), p.4725-4727

1995

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Susceptibility of transgenic mice expressing human apolipoprotein E to closed head injury: The allele E3 is neuroprotective whereas E4 increases fatalities

Neuroscience, 2000-01, Vol.101 (4), p.879-884

2000

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Apolipoprotein E genotyping in the differential diagnosis, not prediction, of Alzheimer's disease

Annals of neurology, 1995-07, Vol.38 (1), p.6-14

Roses, Allen D.

1995

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Risk prediction of prevalent diabetes in a Swiss population using a weighted genetic score--the CoLaus Study

Polyallelic structural variants can provide accurate, highly informative genetic markers focused on diagnosis and therapeutic targets: Accuracy vs. Precision

Genome-wide association study of recurrent major depressive disorder in two European case-control cohorts

A genome-wide association study implicates the APOE locus in nonpathological cognitive ageing

Using Genetics to Enable Studies on the Prevention of Alzheimer's Disease

Efficacy of rosiglitazone in a genetically defined population with mild-to-moderate Alzheimer's disease

Pharmacogenetics and future drug development and delivery

Pharmacogenetics of hypersensitivity to abacavir: from PGx hypothesis to confirmation to clinical utility

Complex disease-associated pharmacogenetics: drug efficacy, drug safety, and confirmation of a pathogenetic hypothesis (Alzheimer's disease)

Gene Dose of Apolipoprotein E Type 4 Allele and the Risk of Alzheimer's Disease in Late Onset Families

Increased Amyloid β-Peptide Deposition in Cerebral Cortex as a Consequence of Apolipoprotein E Genotype in Late-Onset Alzheimer Disease

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

Stimulation of Cholecystokinin-A Receptors With Gl181771X: A Failed Clinical Trial That Did Not Test the Pharmacogenetic Hypothesis for Reduction of Food Intake

Apolipoprotein E Affects the Rate of Alzheimer Disease Expression: (β-Amyloid Burden Is a Secondary Consequence Dependent on APOE Genotype and Duration of Disease

APOLIPOPROTEIN E ALLELES AS RISK FACTORS IN ALZHEIMER'S DISEASE

Apolipoprotein E: High-Avidity Binding to β-Amyloid and Increased Frequency of Type 4 Allele in Late-Onset Familial Alzheimer Disease

Pharmacogenetics

Binding of Human Apolipoprotein E to Synthetic Amyloid β Peptide: Isoform-Specific Effects and Implications for Late-Onset Alzheimer Disease

Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease

SNPing Away at Complex Diseases: Analysis of Single-Nucleotide Polymorphisms around APOE in Alzheimer Disease

A TOMM40 variable-length polymorphism predicts the age of late-onset Alzheimer's disease

Apolipoprotein E and Alzheimer's disease

Apolipoprotein E and Alzheimer Disease

Susceptibility of transgenic mice expressing human apolipoprotein E to closed head injury: The allele E3 is neuroprotective whereas E4 increases fatalities

Apolipoprotein E genotyping in the differential diagnosis, not prediction, of Alzheimer's disease

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