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PEGylation improves the pharmacokinetic properties and ability of interferon gamma to inhibit growth of a human tumor xenograft in athymic mice

Journal of interferon & cytokine research, 2014-10, Vol.34 (10), p.759-768

2014

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Preclinical characterization of pirtobrutinib, a highly selective, noncovalent (reversible) BTK inhibitor

Blood, 2023-07, Vol.142 (1), p.62-72

2023

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Recombinant murine growth hormone from E. coli inclusion bodies: Expression, high-pressure solubilization and refolding, and characterization of activity and structure

Biotechnology progress, 2010-05, Vol.26 (3), p.743-749

2010

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Characterization of a Long-Acting Site-Specific PEGylated Murine GM-CSF Analog and Analysis of Its Hematopoietic Properties in Normal and Cyclophosphamide-Treated Neutropenic Rats

The Protein Journal, 2020-04, Vol.39 (2), p.160-173

2020

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Application of high hydrostatic pressure to dissociate aggregates and refold proteins

Current pharmaceutical biotechnology, 2009-06, Vol.10 (4), p.447-455

2009

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Enhanced Circulating Half-Life and Antitumor Activity of a Site-Specific Pegylated Interferon-α Protein Therapeutic

Bioconjugate chemistry, 2008-01, Vol.19 (1), p.299-305

2008

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A Long-Acting, Highly Potent Interferon α-2 Conjugate Created Using Site-Specific PEGylation

Bioconjugate chemistry, 2005-01, Vol.16 (1), p.200-207

2005

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A Long-Acting, Mono-PEGylated Human Growth Hormone Analog Is a Potent Stimulator of Weight Gain and Bone Growth in Hypophysectomized Rats

Endocrinology (Philadelphia), 2007-04, Vol.148 (4), p.1590-1597

2007

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Site-specific PEGylation enhances the pharmacokinetic properties and antitumor activity of interferon beta-1b

Journal of interferon & cytokine research, 2013-12, Vol.33 (12), p.769-777

2013

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Site-Specific PEGylation of Engineered Cysteine Analogues of Recombinant Human Granulocyte-Macrophage Colony-Stimulating Factor

Bioconjugate chemistry, 2005-09, Vol.16 (5), p.1291-1298

2005

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Design of homogeneous, monopegylated erythropoietin analogs with preserved in vitro bioactivity

Experimental hematology, 2006-06, Vol.34 (6), p.697-704

2006

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In Vivo Pre-Clinical Evaluation of LOXO-305 Alone and in Combination with Venetoclax, Rituximab, R-CHOP or Obinutuzumab on Human Xenograft Lymphoma Tumor Models in Mice

Blood, 2020-11, Vol.136 (Supplement 1), p.32-33

2020

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Site-Specific Protein PEGylation: Application to Cysteine Analogs of Recombinant Human Granulocyte Colony-Stimulating Factor

BioProcess international, 2005-04, Vol.3 (4), p.52-60

2005

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Identification and Characterization of a Pro-tumor Necrosis Factor-α-processing Enzyme from the ADAM Family of Zinc Metalloproteases

The Journal of biological chemistry, 1997-09, Vol.272 (39), p.24588-24593

1997

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Adenosine cyclic 3',5'-monophosphate dependent protein kinase: a new fluorescence displacement titration technique for characterizing the nucleotide binding site on the catalytic subunit

Biochemistry (Easton), 1983-12, Vol.22 (26), p.6310-6317

1983

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A Long-Acting, MonoPEGylated Human Growth Hormone Analog is a Potent Stimulator of Weight Gain and Bone Growth in Hypophysectomized Rats

Endocrinology (Philadelphia), 2007-01, Vol.148 (4), p.1590-1597

2007

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Enhanced Circulating Half-Life and Antitumor Activity of a Site-Specific Pegylated Interferon-[alpha] Protein Therapeutic

Bioconjugate chemistry, 2008-01, Vol.19 (1), p.299

2008

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Adenosine cyclic 3',5'-monophosphate-dependent protein kinase: Interaction of the catalytic subunit and holoenzyme with lin-benzoadenine nucleotides

Biochemistry (Easton), 1983-05, Vol.22 (10), p.2347-2352

1983

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Identification and Characterization of a Pro-tumor Necrosis Factor-Î±-processing Enzyme from the ADAM Family of Zinc Metalloproteases

The Journal of biological chemistry, 1997-09, Vol.272 (39), p.24588

1997

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Beta, delta-peroxy analogs of adenosine and guanosine triphosphate: synthesis and biological activity

Science (American Association for the Advancement of Science), 1982-01, Vol.215, p.81

1982

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β,γ-peroxy Analogs of Adenosine and Guanosine Triphosphate: Synthesis and Biological Activity

Science (American Association for the Advancement of Science), 1982-01, Vol.215 (4528), p.81-82

1982

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Dimensional probing of the ATP binding site on firefly luciferase

Photochemistry and photobiology, 1982-06, Vol.35 (6), p.857-861

1982

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Synthesis and Biological Activity of a Profluorescent Analogue of Coenzyme B12

Proceedings of the National Academy of Sciences - PNAS, 1982-06, Vol.79 (11), p.3480-3484

1982

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Chemotaxis towards sugars by Bacillus subtilis

Journal of general microbiology, 1979-11, Vol.115 (1), p.167-172

1979

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PEGylation improves the pharmacokinetic properties and ability of interferon gamma to inhibit growth of a human tumor xenograft in athymic mice

Preclinical characterization of pirtobrutinib, a highly selective, noncovalent (reversible) BTK inhibitor

Recombinant murine growth hormone from E. coli inclusion bodies: Expression, high-pressure solubilization and refolding, and characterization of activity and structure

Characterization of a Long-Acting Site-Specific PEGylated Murine GM-CSF Analog and Analysis of Its Hematopoietic Properties in Normal and Cyclophosphamide-Treated Neutropenic Rats

Application of high hydrostatic pressure to dissociate aggregates and refold proteins

Enhanced Circulating Half-Life and Antitumor Activity of a Site-Specific Pegylated Interferon-α Protein Therapeutic

A Long-Acting, Highly Potent Interferon α-2 Conjugate Created Using Site-Specific PEGylation

A Long-Acting, Mono-PEGylated Human Growth Hormone Analog Is a Potent Stimulator of Weight Gain and Bone Growth in Hypophysectomized Rats

Site-specific PEGylation enhances the pharmacokinetic properties and antitumor activity of interferon beta-1b

Site-Specific PEGylation of Engineered Cysteine Analogues of Recombinant Human Granulocyte-Macrophage Colony-Stimulating Factor

Design of homogeneous, monopegylated erythropoietin analogs with preserved in vitro bioactivity

In Vivo Pre-Clinical Evaluation of LOXO-305 Alone and in Combination with Venetoclax, Rituximab, R-CHOP or Obinutuzumab on Human Xenograft Lymphoma Tumor Models in Mice

Pirtobrutinib preclinical characterization: a highly selective, non-covalent (reversible) BTK inhibitor

Site-Specific Protein PEGylation: Application to Cysteine Analogs of Recombinant Human Granulocyte Colony-Stimulating Factor

Identification and Characterization of a Pro-tumor Necrosis Factor-α-processing Enzyme from the ADAM Family of Zinc Metalloproteases

Adenosine cyclic 3',5'-monophosphate dependent protein kinase: a new fluorescence displacement titration technique for characterizing the nucleotide binding site on the catalytic subunit

A Long-Acting, MonoPEGylated Human Growth Hormone Analog is a Potent Stimulator of Weight Gain and Bone Growth in Hypophysectomized Rats

Enhanced Circulating Half-Life and Antitumor Activity of a Site-Specific Pegylated Interferon-[alpha] Protein Therapeutic

Adenosine cyclic 3',5'-monophosphate-dependent protein kinase: Interaction of the catalytic subunit and holoenzyme with lin-benzoadenine nucleotides

Identification and Characterization of a Pro-tumor Necrosis Factor-Î±-processing Enzyme from the ADAM Family of Zinc Metalloproteases

Beta, delta-peroxy analogs of adenosine and guanosine triphosphate: synthesis and biological activity

β,γ-peroxy Analogs of Adenosine and Guanosine Triphosphate: Synthesis and Biological Activity

Dimensional probing of the ATP binding site on firefly luciferase

Synthesis and Biological Activity of a Profluorescent Analogue of Coenzyme B12

Chemotaxis towards sugars by Bacillus subtilis

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