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Potential Sources of Inter-Subject Variability in Monoclonal Antibody Pharmacokinetics

Clinical pharmacokinetics, 2016-07, Vol.55 (7), p.789-805

2016

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Application of physiologically based pharmacokinetic models for therapeutic proteins and other novel modalities

Xenobiotica, 2022-08, Vol.52 (8), p.840-854

2022

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A novel fluorescent histamine H1 receptor antagonist demonstrates the advantage of using fluorescence correlation spectroscopy to study the binding of lipophilic ligands

British journal of pharmacology, 2012-03, Vol.165 (6), p.1789-1800

2012

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Learn–confirm in model‐informed drug development: Assessing an immunogenicity quantitative systems pharmacology platform

CPT: pharmacometrics and systems pharmacology, 2023-02, Vol.12 (2), p.139-143

2023

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Quantitative systems pharmacology‐based exploration of relevant anti‐amyloid therapy challenges in clinical practice

Alzheimer's & dementia : translational research & clinical interventions, 2024-04, Vol.10 (2), p.e12474-n/a

2024

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Pharmacokinetics, Pharmacodynamics and Physiologically-Based Pharmacokinetic Modelling of Monoclonal Antibodies

Clinical pharmacokinetics, 2013-02, Vol.52 (2), p.83-124

2013

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The use of PBPK/PD to establish clinically relevant dissolution specifications for zolpidem immediate release tablets

European journal of pharmaceutical sciences, 2020-12, Vol.155, p.105534-105534, Article 105534

2020

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Incorporation of the Time-Varying Postprandial Increase in Splanchnic Blood Flow into a PBPK Model to Predict the Effect of Food on the Pharmacokinetics of Orally Administered High-Extraction Drugs

The AAPS journal, 2017-07, Vol.19 (4), p.1205-1217

2017

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Physiologically-based pharmacokinetic modeling to predict drug-drug interaction of enzalutamide with combined P-gp and CYP3A substrates

Journal of pharmacokinetics and pharmacodynamics, 2023-10, Vol.50 (5), p.365-376

2023

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A novel fluorescent histamine H 1 receptor antagonist demonstrates the advantage of using fluorescence correlation spectroscopy to study the binding of lipophilic ligands

British journal of pharmacology, 2012-03, Vol.165 (6), p.1789-1800

2012

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Applications of linking PBPK and PD models to predict the impact of genotypic variability, formulation differences, differences in target binding capacity and target site drug concentrations on drug responses and variability

Frontiers in pharmacology, 2014-11, Vol.5, p.258-258

2014

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Bimolecular fluorescence complementation: lighting up seven transmembrane domain receptor signalling networks

British journal of pharmacology, 2010-02, Vol.159 (4), p.738-750

2010

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Abstract 2952: Predicting concentration of PARP inhibitors in human tumor tissue using PBPK modeling

Cancer research (Chicago, Ill.), 2019-07, Vol.79 (13_Supplement), p.2952-2952

2019

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A novel fluorescent histamine H, receptor antagonist demonstrates the advantage of using fluorescence correlation spectroscopy to study the binding of lipophilic ligands

British journal of pharmacology, 2012-03, Vol.165 (6), p.1789-1800

2012

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The Effect of Agonist Activation and Homodimerisation on the Membrane Diffusion of the Human Histamine H1 Receptor

Biophysical journal, 2009-02, Vol.96 (3), p.678a-678a

2009

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Coronavirus Disease among Workers in Food Processing, Food Manufacturing, and Agriculture Workplaces

Emerging infectious diseases, 2021-01, Vol.27 (1), p.243-249

2021

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Who is wearing a mask? Gender-, age-, and location-related differences during the COVID-19 pandemic

PloS one, 2020-10, Vol.15 (10), p.e0240785-e0240785

2020

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Climate and Urbanization Drive Mosquito Preference for Humans

Current biology, 2020-09, Vol.30 (18), p.3570-3579.e6

2020

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A re-evaluation of the agronomic effectiveness of the nitrification inhibitors DCD and DMPP and the urease inhibitor NBPT

Agriculture, ecosystems & environment, 2018-01, Vol.252, p.69-73

2018

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The RCSB Protein Data Bank: new resources for research and education

Nucleic acids research, 2013-01, Vol.41 (Database issue), p.D475

2013

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Pod-based e-liquids impair human vascular endothelial cell function

PloS one, 2023-01, Vol.18 (1), p.e0280674-e0280674

2023

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The RCSB Protein Data Bank: views of structural biology for basic and applied research and education

Nucleic acids research, 2015-01, Vol.43 (Database issue), p.D345

2015

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Tau Mislocalization to Dendritic Spines Mediates Synaptic Dysfunction Independently of Neurodegeneration

Neuron (Cambridge, Mass.), 2010-12, Vol.68 (6), p.1067-1081

2010

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Single-cell analysis reveals prognostic fibroblast subpopulations linked to molecular and immunological subtypes of lung cancer

Nature communications, 2023-01, Vol.14 (1), p.387-387, Article 387

2023

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Potential Sources of Inter-Subject Variability in Monoclonal Antibody Pharmacokinetics

Application of physiologically based pharmacokinetic models for therapeutic proteins and other novel modalities

A novel fluorescent histamine H1 receptor antagonist demonstrates the advantage of using fluorescence correlation spectroscopy to study the binding of lipophilic ligands

Learn–confirm in model‐informed drug development: Assessing an immunogenicity quantitative systems pharmacology platform

Quantitative systems pharmacology‐based exploration of relevant anti‐amyloid therapy challenges in clinical practice

Pharmacokinetics, Pharmacodynamics and Physiologically-Based Pharmacokinetic Modelling of Monoclonal Antibodies

The use of PBPK/PD to establish clinically relevant dissolution specifications for zolpidem immediate release tablets

Incorporation of the Time-Varying Postprandial Increase in Splanchnic Blood Flow into a PBPK Model to Predict the Effect of Food on the Pharmacokinetics of Orally Administered High-Extraction Drugs

Physiologically-based pharmacokinetic modeling to predict drug-drug interaction of enzalutamide with combined P-gp and CYP3A substrates

A novel fluorescent histamine H 1 receptor antagonist demonstrates the advantage of using fluorescence correlation spectroscopy to study the binding of lipophilic ligands

Applications of linking PBPK and PD models to predict the impact of genotypic variability, formulation differences, differences in target binding capacity and target site drug concentrations on drug responses and variability

Bimolecular fluorescence complementation: lighting up seven transmembrane domain receptor signalling networks

Abstract 2952: Predicting concentration of PARP inhibitors in human tumor tissue using PBPK modeling

A novel fluorescent histamine H, receptor antagonist demonstrates the advantage of using fluorescence correlation spectroscopy to study the binding of lipophilic ligands

The Effect of Agonist Activation and Homodimerisation on the Membrane Diffusion of the Human Histamine H1 Receptor

Coronavirus Disease among Workers in Food Processing, Food Manufacturing, and Agriculture Workplaces

Who is wearing a mask? Gender-, age-, and location-related differences during the COVID-19 pandemic

Climate and Urbanization Drive Mosquito Preference for Humans

A re-evaluation of the agronomic effectiveness of the nitrification inhibitors DCD and DMPP and the urease inhibitor NBPT

The RCSB Protein Data Bank: new resources for research and education

Pod-based e-liquids impair human vascular endothelial cell function

The RCSB Protein Data Bank: views of structural biology for basic and applied research and education

Tau Mislocalization to Dendritic Spines Mediates Synaptic Dysfunction Independently of Neurodegeneration

The RCSB protein data bank: integrative view of protein, gene and 3D structural information

Single-cell analysis reveals prognostic fibroblast subpopulations linked to molecular and immunological subtypes of lung cancer

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