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Transcriptomic responses are sex-dependent in the skeletal muscle and liver in offspring of obese mice

American journal of physiology: endocrinology and metabolism, 2022-10, Vol.323 (4), p.E336-E353

2022

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Regulation of amino acid transporter trafficking by mTORC1 in primary human trophoblast cells is mediated by the ubiquitin ligase Nedd4-2

Clinical science (1979), 2016-04, Vol.130 (7), p.499-512

2016

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Activation of Placental mTOR Signaling and Amino Acid Transporters in Obese Women Giving Birth to Large Babies

The journal of clinical endocrinology and metabolism, 2013-01, Vol.98 (1), p.105-113

2013

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Adiponectin supplementation in pregnant mice prevents the adverse effects of maternal obesity on placental function and fetal growth

Proceedings of the National Academy of Sciences - PNAS, 2015-10, Vol.112 (41), p.12858-12863

2015

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Increased ubiquitination and reduced plasma membrane trafficking of placental amino acid transporter SNAT-2 in human IUGR

Clinical science (1979), 2015-12, Vol.129 (12), p.1131-1141

2015

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Down-regulation of placental Cdc42 and Rac1 links mTORC2 inhibition to decreased trophoblast amino acid transport in human intrauterine growth restriction

Clinical science (1979), 2020-01, Vol.134 (1), p.53-70

2020

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Down‐regulation of placental mTOR, insulin/IGF‐I signaling, and nutrient transporters in response to maternal nutrient restriction in the baboon

The FASEB journal, 2014-03, Vol.28 (3), p.1294-1305

2014

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Maternal folate deficiency causes inhibition of mTOR signaling, down-regulation of placental amino acid transporters and fetal growth restriction in mice

Scientific reports, 2017-06, Vol.7 (1), p.3982-15, Article 3982

2017

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Overexpression of the LAT1 in primary human trophoblast cells increases the uptake of essential amino acids and activates mTOR signaling

Clinical science (1979), 2023-11, Vol.137 (21), p.1651-1664

2023

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Mechanistic Target of Rapamycin Complex 1 Promotes the Expression of Genes Encoding Electron Transport Chain Proteins and Stimulates Oxidative Phosphorylation in Primary Human Trophoblast Cells by Regulating Mitochondrial Biogenesis

Scientific reports, 2019-01, Vol.9 (1), p.246-246, Article 246

2019

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Maternal glucagon-like peptide-1 is positively associated with fetal growth in pregnancies complicated with obesity

Clinical science (1979), 2023-04, Vol.137 (8), p.663-678

2023

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Placenta-specific Slc38a2/SNAT2 knockdown causes fetal growth restriction in mice

Clinical science (1979), 2021-09, Vol.135 (17), p.2049-2066

2021

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Maternal Protein Restriction in the Rat Inhibits Placental Insulin, mTOR, and STAT3 Signaling and Down-Regulates Placental Amino Acid Transporters

Endocrinology (Philadelphia), 2011-03, Vol.152 (3), p.1119-1129

2011

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Inhibition of mechanistic target of rapamycin signaling decreases levels of O-GlcNAc transferase and increases serotonin release in the human placenta

Clinical science (1979), 2020-12, Vol.134 (23), p.3123-3136

2020

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Placental Remote Control of Fetal Metabolism: Trophoblast mTOR Signaling Regulates Liver IGFBP-1 Phosphorylation and IGF-1 Bioavailability

International journal of molecular sciences, 2023-04, Vol.24 (8), p.7273

2023

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Chronic maternal infusion of full‐length adiponectin in pregnant mice down‐regulates placental amino acid transporter activity and expression and decreases fetal growth

The Journal of physiology, 2012-03, Vol.590 (6), p.1495-1509

2012

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Reduction of In Vivo Placental Amino Acid Transport Precedes the Development of Intrauterine Growth Restriction in the Non-Human Primate

Nutrients, 2021-08, Vol.13 (8), p.2892

2021

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mTORC1 Transcriptional Regulation of Ribosome Subunits, Protein Synthesis, and Molecular Transport in Primary Human Trophoblast Cells

Frontiers in cell and developmental biology, 2020-11, Vol.8, p.583801-583801

2020

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Maternal obesity alters the placental transcriptome in a fetal sex-dependent manner

Frontiers in cell and developmental biology, 2023-06, Vol.11, p.1178533

2023

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Mammalian target of rapamycin signalling modulates amino acid uptake by regulating transporter cell surface abundance in primary human trophoblast cells

The Journal of physiology, 2013-02, Vol.591 (3), p.609-625

2013

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REPLY TO CARBILLON: Fetal/placental weight ratio and placental function

Proceedings of the National Academy of Sciences - PNAS, 2016-01, Vol.113 (3), p.E261-E261

2016

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Mechanistic Target of Rapamycin Complex 2 Regulation of the Primary Human Trophoblast Cell Transcriptome

Frontiers in cell and developmental biology, 2021-11, Vol.9, p.670980-670980

2021

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Normalization of maternal adiponectin in obese pregnant mice prevents programming of impaired glucose metabolism in adult offspring

The FASEB journal, 2022-07, Vol.36 (7), p.e22383-n/a

2022

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Increased placental nutrient transport in a novel mouse model of maternal obesity with fetal overgrowth

Obesity (Silver Spring, Md.), 2015-08, Vol.23 (8), p.1663-1670

2015

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Activation of placental insulin and mTOR signaling in a mouse model of maternal obesity associated with fetal overgrowth

American journal of physiology. Regulatory, integrative and comparative physiology, 2016-01, Vol.310 (1), p.R87-R93

2016

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Transcriptomic responses are sex-dependent in the skeletal muscle and liver in offspring of obese mice

Regulation of amino acid transporter trafficking by mTORC1 in primary human trophoblast cells is mediated by the ubiquitin ligase Nedd4-2

Activation of Placental mTOR Signaling and Amino Acid Transporters in Obese Women Giving Birth to Large Babies

Adiponectin supplementation in pregnant mice prevents the adverse effects of maternal obesity on placental function and fetal growth

Increased ubiquitination and reduced plasma membrane trafficking of placental amino acid transporter SNAT-2 in human IUGR

Down-regulation of placental Cdc42 and Rac1 links mTORC2 inhibition to decreased trophoblast amino acid transport in human intrauterine growth restriction

Down‐regulation of placental mTOR, insulin/IGF‐I signaling, and nutrient transporters in response to maternal nutrient restriction in the baboon

Maternal folate deficiency causes inhibition of mTOR signaling, down-regulation of placental amino acid transporters and fetal growth restriction in mice

Overexpression of the LAT1 in primary human trophoblast cells increases the uptake of essential amino acids and activates mTOR signaling

Mechanistic Target of Rapamycin Complex 1 Promotes the Expression of Genes Encoding Electron Transport Chain Proteins and Stimulates Oxidative Phosphorylation in Primary Human Trophoblast Cells by Regulating Mitochondrial Biogenesis

Maternal glucagon-like peptide-1 is positively associated with fetal growth in pregnancies complicated with obesity

Placenta-specific Slc38a2/SNAT2 knockdown causes fetal growth restriction in mice

Maternal Protein Restriction in the Rat Inhibits Placental Insulin, mTOR, and STAT3 Signaling and Down-Regulates Placental Amino Acid Transporters

Inhibition of mechanistic target of rapamycin signaling decreases levels of O-GlcNAc transferase and increases serotonin release in the human placenta

Placental Remote Control of Fetal Metabolism: Trophoblast mTOR Signaling Regulates Liver IGFBP-1 Phosphorylation and IGF-1 Bioavailability

Chronic maternal infusion of full‐length adiponectin in pregnant mice down‐regulates placental amino acid transporter activity and expression and decreases fetal growth

Reduction of In Vivo Placental Amino Acid Transport Precedes the Development of Intrauterine Growth Restriction in the Non-Human Primate

mTORC1 Transcriptional Regulation of Ribosome Subunits, Protein Synthesis, and Molecular Transport in Primary Human Trophoblast Cells

Maternal obesity alters the placental transcriptome in a fetal sex-dependent manner

Mammalian target of rapamycin signalling modulates amino acid uptake by regulating transporter cell surface abundance in primary human trophoblast cells

REPLY TO CARBILLON: Fetal/placental weight ratio and placental function

Mechanistic Target of Rapamycin Complex 2 Regulation of the Primary Human Trophoblast Cell Transcriptome

Normalization of maternal adiponectin in obese pregnant mice prevents programming of impaired glucose metabolism in adult offspring

Increased placental nutrient transport in a novel mouse model of maternal obesity with fetal overgrowth

Activation of placental insulin and mTOR signaling in a mouse model of maternal obesity associated with fetal overgrowth

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