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IL-10 Alters Immunoproteostasis in APP Mice, Increasing Plaque Burden and Worsening Cognitive Behavior

Neuron (Cambridge, Mass.), 2015-02, Vol.85 (3), p.519-533

2015

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Increased brain hemopexin levels improve outcomes after intracerebral hemorrhage

Journal of cerebral blood flow and metabolism, 2018-06, Vol.38 (6), p.1032-1046

2018

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Amyloid β peptides overexpression in retinal pigment epithelial cells via AAV-mediated gene transfer mimics AMD-like pathology in mice

Scientific reports, 2017-06, Vol.7 (1), p.3222-15, Article 3222

2017

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APP-Mediated Signaling Prevents Memory Decline in Alzheimer’s Disease Mouse Model

Cell reports (Cambridge), 2019-04, Vol.27 (5), p.1345-1355.e6

2019

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Microglia-specific targeting by novel capsid-modified AAV6 vectors

Molecular therapy. Methods & clinical development, 2016-01, Vol.3 (C), p.16026-16026, Article 16026

2016

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Viral expression of ALS-linked ubiquilin-2 mutants causes inclusion pathology and behavioral deficits in mice

Molecular neurodegeneration, 2015-07, Vol.10 (1), p.25-25, Article 25

2015

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Re-Opening the Critical Window for Estrogen Therapy

The Journal of neuroscience, 2015-12, Vol.35 (49), p.16077-16093

2015

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TLR5 decoy receptor as a novel anti-amyloid therapeutic for Alzheimer's disease

The Journal of experimental medicine, 2018-09, Vol.215 (9), p.2247-2264

2018

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Widespread and Efficient Transduction of Spinal Cord and Brain Following Neonatal AAV Injection and Potential Disease Modifying Effect in ALS Mice

Molecular therapy, 2015-01, Vol.23 (1), p.53-62

2015

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Conformational templating of α-synuclein aggregates in neuronal-glial cultures

Molecular neurodegeneration, 2013-05, Vol.8 (1), p.17-17, Article 17

2013

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A human monoclonal IgG that binds aβ assemblies and diverse amyloids exhibits anti-amyloid activities in vitro and in vivo

The Journal of neuroscience, 2015-04, Vol.35 (16), p.6265-6276

2015

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Complex Relationships between Substrate Sequence and Sensitivity to Alterations in γ‑Secretase Processivity Induced by γ‑Secretase Modulators

Biochemistry (Easton), 2014-04, Vol.53 (12), p.1947-1957

2014

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Functionalized intrabodies as potential tau targeting therapy

Alzheimer's & dementia, 2015-07, Vol.11 (7), p.P227-P227

2015

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Modulating chemokine signaling in preclinical Alzheimer's disease models

Alzheimer's & dementia, 2015-07, Vol.11 (7), p.P157-P157

2015

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391. Increased Levels of Amyloid β Peptides in RPE via AAV-Mediated Gene Transfer Mimics AMD-Like Pathology in Mice

Molecular therapy, 2015-05, Vol.23, p.S155-S155

2015

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Re-Opening the Critical Windowfor Estrogen Therapy

The Journal of neuroscience, 2015-12, Vol.35 (49), p.16077-16093

2015

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O3‐04‐06: Functionalized intrabodies as potential tau targeting therapy

Alzheimer's & dementia, 2015-07, Vol.11 (7S_Part_5), p.P227-P227

2015

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O1‐11‐03: Modulating chemokine signaling in preclinical Alzheimer's disease models

Alzheimer's & dementia, 2015-07, Vol.11 (7S_Part_3), p.P157-P157

2015

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Conformational templating of [alpha]-synuclein aggregates in neuronal-glial cultures

Molecular neurodegeneration, 2013-05, Vol.8 (1), p.17-17

2013

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IL-10 Alters Immunoproteostasis in APP Mice, Increasing Plaque Burden and Worsening Cognitive Behavior

Increased brain hemopexin levels improve outcomes after intracerebral hemorrhage

Amyloid β peptides overexpression in retinal pigment epithelial cells via AAV-mediated gene transfer mimics AMD-like pathology in mice

APP-Mediated Signaling Prevents Memory Decline in Alzheimer’s Disease Mouse Model

Microglia-specific targeting by novel capsid-modified AAV6 vectors

Viral expression of ALS-linked ubiquilin-2 mutants causes inclusion pathology and behavioral deficits in mice

Re-Opening the Critical Window for Estrogen Therapy

TLR5 decoy receptor as a novel anti-amyloid therapeutic for Alzheimer's disease

Widespread and Efficient Transduction of Spinal Cord and Brain Following Neonatal AAV Injection and Potential Disease Modifying Effect in ALS Mice

Conformational templating of α-synuclein aggregates in neuronal-glial cultures

A human monoclonal IgG that binds aβ assemblies and diverse amyloids exhibits anti-amyloid activities in vitro and in vivo

Complex Relationships between Substrate Sequence and Sensitivity to Alterations in γ‑Secretase Processivity Induced by γ‑Secretase Modulators

Functionalized intrabodies as potential tau targeting therapy

Modulating chemokine signaling in preclinical Alzheimer's disease models

FROM SYSTEMS LEVEL TRANSCRIPTOMICS TO NEW IMMUNE TARGETS FOR ALZHEIMER’S DISEASE

391. Increased Levels of Amyloid β Peptides in RPE via AAV-Mediated Gene Transfer Mimics AMD-Like Pathology in Mice

Re-Opening the Critical Windowfor Estrogen Therapy

O3‐04‐06: Functionalized intrabodies as potential tau targeting therapy

O1‐11‐03: Modulating chemokine signaling in preclinical Alzheimer's disease models

F2‐01‐04: From Systems Level Transcriptomics to new Immune Targets for Alzheimer’s Disease

Conformational templating of [alpha]-synuclein aggregates in neuronal-glial cultures

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