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Enzymatic Ketonization of 2-Hydroxymuconate: Specificity and Mechanism Investigated by the Crystal Structures of Two Isomerases

Biochemistry (Easton), 1996-01, Vol.35 (3), p.792-802

1996

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Active membrane transport and receptor proteins from bacteria

Biochemical Society transactions, 2005-08, Vol.33 (Pt 4), p.867-872

2005

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Understanding the mechanism of ice binding by type III antifreeze proteins

Journal of molecular biology, 2001-01, Vol.305 (4), p.875-889

2001

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The Molecular Basis of Vancomycin Resistance in Clinically Relevant Enterococci: Crystal Structure of D-Alanyl-D-Lactate Ligase (VanA)

Proceedings of the National Academy of Sciences - PNAS, 2000-08, Vol.97 (16), p.8921-8925

2000

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Subcloning and nucleotide sequence of the 3,4-dihydroxyphenylacetate (homoprotocatechuate) 2,3-dioxygenase gene from Escherichia coli C

FEBS letters, 1990-11, Vol.275 (1), p.53-57

1990

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PhD students

Nature (London), 1990-03, Vol.344 (6261), p.10-10

ROPER, D. I

1990

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A road map for prioritizing warheads for cysteine targeting covalent inhibitors

European journal of medicinal chemistry, 2018-12, Vol.160, p.94-107

2018

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Purification, some properties and nucleotide sequence of 5-carboxymethyl-2-hydroxymuconate isomerase of Escherichia coli C

FEBS letters, 1990-06, Vol.266 (1), p.63-66

1990

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The Escherichia coli C homoprotocatechuate degradative operon: hpc gene order, direction of transcription and control of expression

Molecular & general genetics, 1993-02, Vol.237 (1-2), p.241-250

1993

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Purification, nucleotide sequence and some properties of a bifunctional isomerase/decarboxylase from the homoprotocatechuate degradative pathway of Escherichia coli C

European journal of biochemistry, 1993-10, Vol.217 (2), p.575-580

1993

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Crystallization and preliminary X-ray characterization of VanA from Enterococcus faecium BM4147: towards the molecular basis of bacterial resistance to the glycopeptide antibiotic vancomycin

Acta crystallographica. Section D, Biological crystallography., 1999-08, Vol.55 (8), p.1481-1483

1999

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Crystallization and preliminary X-ray analysis of a bifunctional enzyme: HHDD isomerase/OPET decarboxylase from Escherichia coli

Acta crystallographica. Section D, Biological crystallography., 1996-09, Vol.52 (5), p.1036-1038

1996

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Preliminary crystallographic analysis of 5-carboxymethyl-2-hydroxymuconate isomerase from Escherichia coli

Journal of molecular biology, 1989-12, Vol.210 (4), p.881-882

1989

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Sequence of the hpcC and hpcG genes of the meta-fission homoprotocatechuic acid pathway of Escherichia coli C: nearly 40% amino-acid identity with the analogous enzymes of the catechol pathway

Gene, 1995-04, Vol.156 (1), p.47-51

1995

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Crystal Structure of Penicillin Binding Protein 4 (dacB) from Escherichia coli, both in the Native Form and Covalently Linked to Various Antibiotics

Biochemistry (Easton), 2006-01, Vol.45 (3), p.783-792

2006

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Allosteric Activation in Bacillus stearothermophilus Lactate Dehydrogenase Investigated by an X-ray Crystallographic Analysis of a Mutant Designed to Prevent Tetramerization of the Enzyme

Journal of molecular biology, 1994-05, Vol.238 (4), p.615-625

1994

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Preliminary crystallographic analysis of 4-oxalocrotonate tautomerase reveals the oligomeric structure of the enzyme

Journal of molecular biology, 1994-11, Vol.243 (4), p.799-801

1994

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Structure and Mechanism of HpcH: A Metal Ion Dependent Class II Aldolase from the Homoprotocatechuate Degradation Pathway of Escherichia coli

Journal of molecular biology, 2007-11, Vol.373 (4), p.866-876

2007

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Vancomycin resistance in enterococci: reprogramming of the d-Ala– d-Ala ligases in bacterial peptidoglycan biosynthesis

Chemistry & Biology, 2000-05, Vol.7 (5), p.R109-R119

2000

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Structural Characterisation of the Insecticidal Toxin XptA1, Reveals a 1.15 MDa Tetramer with a Cage-like Structure

Journal of molecular biology, 2007-03, Vol.366 (5), p.1558-1568

2007

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The structural consequences of exchanging tryptophan and tyrosine residues in B. stearothermophilus lactate dehydrogenase

Protein engineering, 1992-10, Vol.5 (7), p.611-615

1992

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Structure/Function Studies on a S-Adenosyl- l-methionine-dependent Uroporphyrinogen III C Methyltransferase (SUMT), a Key Regulatory Enzyme of Tetrapyrrole Biosynthesis

Journal of molecular biology, 2004-11, Vol.344 (2), p.419-433

2004

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A De Novo Designed Inhibitor of D-Ala-D-Ala Ligase from E. coli

Angewandte Chemie International Edition, 2005-10, Vol.44 (39), p.6403-6406

2005

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Structure and Mechanism of HpcG, a Hydratase in the Homoprotocatechuate Degradation Pathway of Escherichia coli

Journal of molecular biology, 2007-07, Vol.370 (5), p.899-911

2007

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Mutations in the DNA Mismatch Repair Proteins MutS and MutL of Oxazolidinone-Resistant or -Susceptible Enterococcus faecium

Antimicrobial Agents and Chemotherapy, 2003-10, Vol.47 (10), p.3061-3066

2003

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Enzymatic Ketonization of 2-Hydroxymuconate: Specificity and Mechanism Investigated by the Crystal Structures of Two Isomerases

Active membrane transport and receptor proteins from bacteria

Understanding the mechanism of ice binding by type III antifreeze proteins

The Molecular Basis of Vancomycin Resistance in Clinically Relevant Enterococci: Crystal Structure of D-Alanyl-D-Lactate Ligase (VanA)

Subcloning and nucleotide sequence of the 3,4-dihydroxyphenylacetate (homoprotocatechuate) 2,3-dioxygenase gene from Escherichia coli C

PhD students

A road map for prioritizing warheads for cysteine targeting covalent inhibitors

Purification, some properties and nucleotide sequence of 5-carboxymethyl-2-hydroxymuconate isomerase of Escherichia coli C

The Escherichia coli C homoprotocatechuate degradative operon: hpc gene order, direction of transcription and control of expression

Purification, nucleotide sequence and some properties of a bifunctional isomerase/decarboxylase from the homoprotocatechuate degradative pathway of Escherichia coli C

Crystallization and preliminary X-ray characterization of VanA from Enterococcus faecium BM4147: towards the molecular basis of bacterial resistance to the glycopeptide antibiotic vancomycin

Crystallization and preliminary X-ray analysis of a bifunctional enzyme: HHDD isomerase/OPET decarboxylase from Escherichia coli

Preliminary crystallographic analysis of 5-carboxymethyl-2-hydroxymuconate isomerase from Escherichia coli

Sequence of the hpcC and hpcG genes of the meta-fission homoprotocatechuic acid pathway of Escherichia coli C: nearly 40% amino-acid identity with the analogous enzymes of the catechol pathway

Crystal Structure of Penicillin Binding Protein 4 (dacB) from Escherichia coli, both in the Native Form and Covalently Linked to Various Antibiotics

Allosteric Activation in Bacillus stearothermophilus Lactate Dehydrogenase Investigated by an X-ray Crystallographic Analysis of a Mutant Designed to Prevent Tetramerization of the Enzyme

Preliminary crystallographic analysis of 4-oxalocrotonate tautomerase reveals the oligomeric structure of the enzyme

Structure and Mechanism of HpcH: A Metal Ion Dependent Class II Aldolase from the Homoprotocatechuate Degradation Pathway of Escherichia coli

Vancomycin resistance in enterococci: reprogramming of the d-Ala– d-Ala ligases in bacterial peptidoglycan biosynthesis

Structural Characterisation of the Insecticidal Toxin XptA1, Reveals a 1.15 MDa Tetramer with a Cage-like Structure

The structural consequences of exchanging tryptophan and tyrosine residues in B. stearothermophilus lactate dehydrogenase

Structure/Function Studies on a S-Adenosyl- l-methionine-dependent Uroporphyrinogen III C Methyltransferase (SUMT), a Key Regulatory Enzyme of Tetrapyrrole Biosynthesis

A De Novo Designed Inhibitor of D-Ala-D-Ala Ligase from E. coli

Structure and Mechanism of HpcG, a Hydratase in the Homoprotocatechuate Degradation Pathway of Escherichia coli

Mutations in the DNA Mismatch Repair Proteins MutS and MutL of Oxazolidinone-Resistant or -Susceptible Enterococcus faecium

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