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The role of oxidative stress in blood–brain barrier disruption during ischemic stroke: Antioxidants in clinical trials

Biochemical pharmacology, 2024-03, p.116186-116186, Article 116186

2024

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Sex differences in physiological response to increased neuronal excitability in a knockin mouse model of pediatric epilepsy

Clinical science (1979), 2024-02, Vol.138 (4), p.205

2024

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Blood-brain barrier transporters: a translational consideration for CNS delivery of neurotherapeutics

Expert opinion on drug delivery, 2024, Vol.21 (1), p.71-89

2024

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CNS Drug Delivery in Stroke: Improving Therapeutic Translation From the Bench to the Bedside

Stroke (1970), 2024-01, Vol.55 (1), p.190

2024

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Oatp (Organic Anion Transporting Polypeptide)-Mediated Transport: A Mechanism for Atorvastatin Neuroprotection in Stroke

Stroke (1970), 2023-11, Vol.54 (11), p.2875

2023

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High Resolution Multiplex Confocal Imaging of the Neurovascular Unit in Health and Experimental Ischemic Stroke

Cells (Basel, Switzerland), 2023-02, Vol.12 (4), p.645

2023

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Abstract WP244: Localization And Expression Of Transporters For Cationic Drugs At The Blood-brain Barrier: Relevance To The Pharmacotherapy Of Ischemic Stroke

Stroke (1970), 2023-02, Vol.54 (Suppl_1)

2023

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Abstract TP205: Organic Anion Transporting Polypeptides: Endogenous Blood-brain Barrier Transporters That Are Required For Statins To Exert Neuroprotective Effects In Ischemic Stroke

Stroke (1970), 2023-02, Vol.54 (Suppl_1)

2023

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Abstract TP209: Role Of Endoglin In The Regulation Of Organic Anion Transporting Polypeptide 1a4 At The Blood-brain Barrier: Relevance To The Treatment Of Ischemic Stroke

Stroke (1970), 2023-02, Vol.54 (Suppl_1)

2023

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Methods to Study Drug Uptake at the Blood-Brain Barrier Following Experimental Ischemic Stroke: In Vitro and In Vivo Approaches

Methods in molecular biology (Clifton, N.J.), 2023, Vol.2616, p.403

2023

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Targeting organic cation transporters at the blood-brain barrier to treat ischemic stroke in rats

Experimental neurology, 2022-11, Vol.357, p.114181-114181, Article 114181

2022

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Transport Mechanisms at the Blood–Brain Barrier and in Cellular Compartments of the Neurovascular Unit: Focus on CNS Delivery of Small Molecule Drugs

Pharmaceutics, 2022-07, Vol.14 (7), p.1501

2022

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Regulation of Blood-Brain Barrier Transporters by Transforming Growth Factor- β /Activin Receptor-Like Kinase 1 Signaling: Relevance to the Brain Disposition of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Inhibitors (i.e., Statins)

Drug metabolism and disposition, 2022-07, Vol.50 (7), p.942-956

2022

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High-Dose Acetaminophen Alters the Integrity of the Blood-Brain Barrier and Leads to Increased CNS Uptake of Codeine in Rats

Pharmaceutics, 2022-04, Vol.14 (5), p.949

2022

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Blood-Brain Barrier Transporters: Opportunities for Therapeutic Development in Ischemic Stroke

International journal of molecular sciences, 2022-02, Vol.23 (3), p.1898

2022

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DRUG TRANSPORT IN THE BRAIN

Drug Transporters, 2022, p.283-317

2022

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Transport Properties of Statins by Organic Anion Transporting Polypeptide 1A2 and Regulation by Transforming Growth Factor- β Signaling in Human Endothelial Cells

The Journal of pharmacology and experimental therapeutics, 2021-02, Vol.376 (2), p.148

2021

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Organic Cation Transporter (OCT/OCTN) Expression at Brain Barrier Sites: Focus on CNS Drug Delivery

Organic Cation Transporters in the Central Nervous System, 2021, Vol.266, p.301-328

2021

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Regulation of blood–brain barrier integrity by microglia in health and disease: A therapeutic opportunity

Journal of Cerebral Blood Flow & Metabolism, 2020-12, Vol.40 (1_suppl), p.S6-S24

2020

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Structure, Function, and Regulation of the Blood-Brain Barrier Tight Junction in Central Nervous System Disorders

Frontiers in physiology, 2020-08, Vol.11, p.914

2020

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Transporter-Mediated Delivery of Small Molecule Drugs to the Brain: A Critical Mechanism That Can Advance Therapeutic Development for Ischemic Stroke

Pharmaceutics, 2020-02, Vol.12 (2), p.154

2020

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Abstract TP121: Organic Anion Transporting Polypeptide (Oatp)-Mediated Transport is Required for Statin-Induced Neuroprotection: A Role for Blood-Brain Barrier Transporters in Stroke Treatment

Stroke (1970), 2020-02, Vol.51 (Suppl_1)

2020

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Distribution of insulin in trigeminal nerve and brain after intranasal administration

Scientific reports, 2019-02, Vol.9 (1), p.2621-2621, Article 2621

2019

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Functional Expression of Organic Anion Transporting Polypeptide 1a4 Is Regulated by Transforming Growth Factor- β /Activin Receptor-like Kinase 1 Signaling at the Blood-Brain Barrier

Molecular pharmacology, 2018-12, Vol.94 (6), p.1321-1333

2018

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Sex-specific differences in organic anion transporting polypeptide 1a4 (Oatp1a4) functional expression at the blood-brain barrier in Sprague-Dawley rats

Fluids and barriers of the CNS, 2018-09, Vol.15 (1), p.25-25, Article 25

2018

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The role of oxidative stress in blood–brain barrier disruption during ischemic stroke: Antioxidants in clinical trials

Sex differences in physiological response to increased neuronal excitability in a knockin mouse model of pediatric epilepsy

Blood-brain barrier transporters: a translational consideration for CNS delivery of neurotherapeutics

CNS Drug Delivery in Stroke: Improving Therapeutic Translation From the Bench to the Bedside

Oatp (Organic Anion Transporting Polypeptide)-Mediated Transport: A Mechanism for Atorvastatin Neuroprotection in Stroke

High Resolution Multiplex Confocal Imaging of the Neurovascular Unit in Health and Experimental Ischemic Stroke

Abstract WP244: Localization And Expression Of Transporters For Cationic Drugs At The Blood-brain Barrier: Relevance To The Pharmacotherapy Of Ischemic Stroke

Abstract TP205: Organic Anion Transporting Polypeptides: Endogenous Blood-brain Barrier Transporters That Are Required For Statins To Exert Neuroprotective Effects In Ischemic Stroke

Abstract TP209: Role Of Endoglin In The Regulation Of Organic Anion Transporting Polypeptide 1a4 At The Blood-brain Barrier: Relevance To The Treatment Of Ischemic Stroke

Methods to Study Drug Uptake at the Blood-Brain Barrier Following Experimental Ischemic Stroke: In Vitro and In Vivo Approaches

Targeting organic cation transporters at the blood-brain barrier to treat ischemic stroke in rats

Transport Mechanisms at the Blood–Brain Barrier and in Cellular Compartments of the Neurovascular Unit: Focus on CNS Delivery of Small Molecule Drugs

Regulation of Blood-Brain Barrier Transporters by Transforming Growth Factor- β /Activin Receptor-Like Kinase 1 Signaling: Relevance to the Brain Disposition of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Inhibitors (i.e., Statins)

High-Dose Acetaminophen Alters the Integrity of the Blood-Brain Barrier and Leads to Increased CNS Uptake of Codeine in Rats

Blood-Brain Barrier Transporters: Opportunities for Therapeutic Development in Ischemic Stroke

DRUG TRANSPORT IN THE BRAIN

Transport Properties of Statins by Organic Anion Transporting Polypeptide 1A2 and Regulation by Transforming Growth Factor- β Signaling in Human Endothelial Cells

Organic Cation Transporter (OCT/OCTN) Expression at Brain Barrier Sites: Focus on CNS Drug Delivery

Regulation of blood–brain barrier integrity by microglia in health and disease: A therapeutic opportunity

Structure, Function, and Regulation of the Blood-Brain Barrier Tight Junction in Central Nervous System Disorders

Transporter-Mediated Delivery of Small Molecule Drugs to the Brain: A Critical Mechanism That Can Advance Therapeutic Development for Ischemic Stroke

Abstract TP121: Organic Anion Transporting Polypeptide (Oatp)-Mediated Transport is Required for Statin-Induced Neuroprotection: A Role for Blood-Brain Barrier Transporters in Stroke Treatment

Distribution of insulin in trigeminal nerve and brain after intranasal administration

Functional Expression of Organic Anion Transporting Polypeptide 1a4 Is Regulated by Transforming Growth Factor- β /Activin Receptor-like Kinase 1 Signaling at the Blood-Brain Barrier

Sex-specific differences in organic anion transporting polypeptide 1a4 (Oatp1a4) functional expression at the blood-brain barrier in Sprague-Dawley rats

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