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Blood-brain barrier dysfunction in ischemic stroke: targeting tight junctions and transporters for vascular protection

American Journal of Physiology: Cell Physiology, 2018-09, Vol.315 (3), p.C343-C356

2018

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Regulation of blood–brain barrier integrity by microglia in health and disease: A therapeutic opportunity

Journal of Cerebral Blood Flow & Metabolism, 2020-12, Vol.40 (1_suppl), p.S6-S24

2020

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Structure, Function, and Regulation of the Blood-Brain Barrier Tight Junction in Central Nervous System Disorders

Frontiers in physiology, 2020-08, Vol.11, p.914

2020

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Blood-brain barrier integrity and glial support: mechanisms that can be targeted for novel therapeutic approaches in stroke

Current pharmaceutical design, 2012-08, Vol.18 (25), p.3624

2012

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Transporters at CNS barrier sites: obstacles or opportunities for drug delivery?

Current pharmaceutical design, 2014-03, Vol.20 (10), p.1422

2014

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Distribution of insulin in trigeminal nerve and brain after intranasal administration

Scientific reports, 2019-02, Vol.9 (1), p.2621-2621, Article 2621

2019

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Functional Expression of P-glycoprotein and Organic Anion Transporting Polypeptides at the Blood-Brain Barrier: Understanding Transport Mechanisms for Improved CNS Drug Delivery?

The AAPS journal, 2017-07, Vol.19 (4), p.931-939

2017

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Hypoxic Stress and Inflammatory Pain Disrupt Blood-Brain Barrier Tight Junctions: Implications for Drug Delivery to the Central Nervous System

The AAPS journal, 2017-07, Vol.19 (4), p.910-920

2017

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Transport Mechanisms at the Blood–Brain Barrier and in Cellular Compartments of the Neurovascular Unit: Focus on CNS Delivery of Small Molecule Drugs

Pharmaceutics, 2022-07, Vol.14 (7), p.1501

2022

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Blood-Brain Barrier Transporters: Opportunities for Therapeutic Development in Ischemic Stroke

International journal of molecular sciences, 2022-02, Vol.23 (3), p.1898

2022

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HIV‐1 viral envelope glycoprotein gp120 produces oxidative stress and regulates the functional expression of multidrug resistance protein‐1 (Mrp1) in glial cells

Journal of neurochemistry, 2008-08, Vol.106 (3), p.1298-1313

2008

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Sex differences in physiological response to increased neuronal excitability in a knockin mouse model of pediatric epilepsy

Clinical science (1979), 2024-02, Vol.138 (4), p.205

2024

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HIV-1 Viral Envelope Glycoprotein gp120 Triggers an Inflammatory Response in Cultured Rat Astrocytes and Regulates the Functional Expression of P-Glycoprotein

Molecular pharmacology, 2006-09, Vol.70 (3), p.1087-1098

2006

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In Situ Localization of P-glycoprotein (ABCB1) in Human and Rat Brain

The journal of histochemistry and cytochemistry, 2006-10, Vol.54 (10), p.1159-1167

2006

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Sex-specific differences in organic anion transporting polypeptide 1a4 (Oatp1a4) functional expression at the blood-brain barrier in Sprague-Dawley rats

Fluids and barriers of the CNS, 2018-09, Vol.15 (1), p.25-25, Article 25

2018

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Transporter-Mediated Delivery of Small Molecule Drugs to the Brain: A Critical Mechanism That Can Advance Therapeutic Development for Ischemic Stroke

Pharmaceutics, 2020-02, Vol.12 (2), p.154

2020

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Hypoxia/Reoxygenation Stress Signals an Increase in Organic Anion Transporting polypeptide 1a4 (Oatp1a4) at the Blood–Brain Barrier: Relevance to CNS Drug Delivery

Journal of cerebral blood flow and metabolism, 2014-04, Vol.34 (4), p.699-707

2014

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P-glycoprotein trafficking at the blood-brain barrier altered by peripheral inflammatory hyperalgesia

Journal of neurochemistry, 2012-09, Vol.122 (5), p.962-975

2012

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Acetaminophen modulates P-glycoprotein functional expression at the blood-brain barrier by a constitutive androstane receptor-dependent mechanism

Molecular pharmacology, 2013-11, Vol.84 (5), p.774-786

2013

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Role of Transporters in Central Nervous System Drug Delivery and Blood-Brain Barrier Protection: Relevance to Treatment of Stroke

Journal of Central Nervous System Disease, 2017-04, Vol.2017 (9), p.1179573517693802-1179573517693802

2017

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P-glycoprotein modulates morphine uptake into the CNS: a role for the non-steroidal anti-inflammatory drug diclofenac

PloS one, 2014-02, Vol.9 (2), p.e88516

2014

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Modulation of Opioid Transport at the Blood-Brain Barrier by Altered ATP-Binding Cassette (ABC) Transporter Expression and Activity

Pharmaceutics, 2018-10, Vol.10 (4), p.192

2018

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Up-regulation of P-glycoprotein by HIV protease inhibitors in a human brain microvessel endothelial cell line

Journal of neuroscience research, 2009-03, Vol.87 (4), p.1023-1036

2009

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Inflammatory pain signals an increase in functional expression of organic anion transporting polypeptide 1a4 at the blood-brain barrier

The Journal of pharmacology and experimental therapeutics, 2011-03, Vol.336 (3), p.827

2011

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High Resolution Multiplex Confocal Imaging of the Neurovascular Unit in Health and Experimental Ischemic Stroke

Cells (Basel, Switzerland), 2023-02, Vol.12 (4), p.645

2023

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Blood-brain barrier dysfunction in ischemic stroke: targeting tight junctions and transporters for vascular protection

Regulation of blood–brain barrier integrity by microglia in health and disease: A therapeutic opportunity

Structure, Function, and Regulation of the Blood-Brain Barrier Tight Junction in Central Nervous System Disorders

Blood-brain barrier integrity and glial support: mechanisms that can be targeted for novel therapeutic approaches in stroke

Transporters at CNS barrier sites: obstacles or opportunities for drug delivery?

Distribution of insulin in trigeminal nerve and brain after intranasal administration

Functional Expression of P-glycoprotein and Organic Anion Transporting Polypeptides at the Blood-Brain Barrier: Understanding Transport Mechanisms for Improved CNS Drug Delivery?

Hypoxic Stress and Inflammatory Pain Disrupt Blood-Brain Barrier Tight Junctions: Implications for Drug Delivery to the Central Nervous System

Transport Mechanisms at the Blood–Brain Barrier and in Cellular Compartments of the Neurovascular Unit: Focus on CNS Delivery of Small Molecule Drugs

Blood-Brain Barrier Transporters: Opportunities for Therapeutic Development in Ischemic Stroke

HIV‐1 viral envelope glycoprotein gp120 produces oxidative stress and regulates the functional expression of multidrug resistance protein‐1 (Mrp1) in glial cells

Sex differences in physiological response to increased neuronal excitability in a knockin mouse model of pediatric epilepsy

HIV-1 Viral Envelope Glycoprotein gp120 Triggers an Inflammatory Response in Cultured Rat Astrocytes and Regulates the Functional Expression of P-Glycoprotein

In Situ Localization of P-glycoprotein (ABCB1) in Human and Rat Brain

Sex-specific differences in organic anion transporting polypeptide 1a4 (Oatp1a4) functional expression at the blood-brain barrier in Sprague-Dawley rats

Transporter-Mediated Delivery of Small Molecule Drugs to the Brain: A Critical Mechanism That Can Advance Therapeutic Development for Ischemic Stroke

Hypoxia/Reoxygenation Stress Signals an Increase in Organic Anion Transporting polypeptide 1a4 (Oatp1a4) at the Blood–Brain Barrier: Relevance to CNS Drug Delivery

P-glycoprotein trafficking at the blood-brain barrier altered by peripheral inflammatory hyperalgesia

Acetaminophen modulates P-glycoprotein functional expression at the blood-brain barrier by a constitutive androstane receptor-dependent mechanism

Role of Transporters in Central Nervous System Drug Delivery and Blood-Brain Barrier Protection: Relevance to Treatment of Stroke

P-glycoprotein modulates morphine uptake into the CNS: a role for the non-steroidal anti-inflammatory drug diclofenac

Modulation of Opioid Transport at the Blood-Brain Barrier by Altered ATP-Binding Cassette (ABC) Transporter Expression and Activity

Up-regulation of P-glycoprotein by HIV protease inhibitors in a human brain microvessel endothelial cell line

Inflammatory pain signals an increase in functional expression of organic anion transporting polypeptide 1a4 at the blood-brain barrier

High Resolution Multiplex Confocal Imaging of the Neurovascular Unit in Health and Experimental Ischemic Stroke

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