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Resveratrol regulates the PTEN/AKT pathway through androgen receptor-dependent and -independent mechanisms in prostate cancer cell lines

Human molecular genetics, 2010-11, Vol.19 (22), p.4319-4329

2010

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SARS-CoV-2 3CL-protease inhibitors derived from ML300: investigation of P1 and replacements of the 1,2,3-benzotriazole

Medicinal chemistry research, 2023-07, Vol.32 (7), p.1383-1390

2023

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MC1R signaling through the cAMP-CREB/ATF-1 and ERK-NFκB pathways accelerates G1/S transition promoting breast cancer progression

NPJ precision oncology, 2023-09, Vol.7 (1), p.85-85, Article 85

2023

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The ERK1/2 pathway modulates nuclear PTEN-mediated cell cycle arrest by cyclin D1 transcriptional regulation

Human molecular genetics, 2006-09, Vol.15 (17), p.2553-2559

2006

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Characterization of cryptic splicing in germline PTEN intronic variants in Cowden syndrome

Human mutation, 2017-10, Vol.38 (10), p.1372-1377

2017

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PTEN interacts with RNA polymerase II to dephosphorylate polymerase II C-terminal domain

Oncotarget, 2019-08, Vol.10 (48), p.4951-4959

2019

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PTEN modulates gene transcription by redistributing genome-wide RNA polymerase II occupancy

Human molecular genetics, 2019-09, Vol.28 (17), p.2826-2834

2019

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Neural transcriptome of constitutional Pten dysfunction in mice and its relevance to human idiopathic autism spectrum disorder

Molecular psychiatry, 2016-01, Vol.21 (1), p.118-125

2016

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Redefining the PTEN promoter: identification of novel upstream transcription start regions

Human molecular genetics, 2021-11, Vol.30 (22), p.2135-2148

2021

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CDK9 Inhibition by Dinaciclib Is a Therapeutic Vulnerability in Epithelioid Hemangioendothelioma

Clinical cancer research, 2024-09, Vol.30 (18), p.4179-4189

2024

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Germline disruption of Pten localization causes enhanced sex-dependent social motivation and increased glial production

Human molecular genetics, 2014-06, Vol.23 (12), p.3212-3227

2014

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Characterization of cryptic splicing in germline PTEN intronic variants in Cowden syndrome: CHEN et al

Human mutation, 2017-10, Vol.38 (10), p.1372-1377

2017

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Germline EGFR mutation and cancer predisposition in adolescent and young adult (AYA) females with adrenocortical carcinoma

Journal of clinical oncology, 2019-05, Vol.37 (15_suppl), p.e13014-e13014

2019

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Activation of AR sensitizes breast carcinomas to NVP-BEZ235's therapeutic effect mediated by PTEN and KLLN upregulation

Molecular cancer therapeutics, 2014-02, Vol.13 (2), p.517-527

2014

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Germline compound heterozygous poly-glutamine deletion in USF3 may be involved in predisposition to heritable and sporadic epithelial thyroid carcinoma

Human molecular genetics, 2017-01, Vol.26 (2), p.243-257

2017

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Exome Sequencing Reveals Germline SMAD9 Mutation That Reduces Phosphatase and Tensin Homolog Expression and Is Associated With Hamartomatous Polyposis and Gastrointestinal Ganglioneuromas

Gastroenterology (New York, N.Y. 1943), 2015-10, Vol.149 (4), p.886-889.e5

2015

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Disruption of transforming growth factor-beta signaling by five frequently methylated genes leads to head and neck squamous cell carcinoma pathogenesis

Cancer research (Chicago, Ill.), 2009-12, Vol.69 (24), p.9301-9305

2009

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Germline mutations in MSR1, ASCC1, and CTHRC1 in patients with Barrett esophagus and esophageal adenocarcinoma

JAMA : the journal of the American Medical Association, 2011-07, Vol.306 (4), p.410

2011

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1. Germline EGFR variants over-represented in adolescent and young adult (AYA) females with adrenocortical carcinoma

Cancer genetics, 2020-06, Vol.244, p.1-1

2020

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AP-2alpha induces epigenetic silencing of tumor suppressive genes and microsatellite instability in head and neck squamous cell carcinoma

PloS one, 2009-09, Vol.4 (9), p.e6931-e6931

2009

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Cowden Syndrome-Related Mutations in PTEN Associate with Enhanced Proteasome Activity

Cancer research (Chicago, Ill.), 2013-05, Vol.73 (10), p.3029-3040

2013

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PTEN Lipid Phosphatase Activity and Proper Subcellular Localization Are Necessary and Sufficient for Down-Regulating AKT Phosphorylation in the Nucleus in Cowden Syndrome

The journal of clinical endocrinology and metabolism, 2012-11, Vol.97 (11), p.E2179-E2187

2012

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Cytoplasm-predominant Pten associates with increased region-specific brain tyrosine hydroxylase and dopamine D2 receptors in mouse model with autistic traits

Molecular autism, 2015-11, Vol.6 (56), p.63-63, Article 63

2015

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Utility of PTEN Protein Dosage in Predicting for Underlying Germline PTEN Mutations among Patients Presenting with Thyroid Cancer and Cowden-Like Phenotypes

The journal of clinical endocrinology and metabolism, 2012-12, Vol.97 (12), p.E2320-E2327

2012

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AP-2[alpha] Induces Epigenetic Silencing of Tumor Suppressive Genes and Microsatellite Instability in Head and Neck Squamous Cell Carcinoma

PloS one, 2009-09, Vol.4 (9), p.e6931

2009

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Resveratrol regulates the PTEN/AKT pathway through androgen receptor-dependent and -independent mechanisms in prostate cancer cell lines

SARS-CoV-2 3CL-protease inhibitors derived from ML300: investigation of P1 and replacements of the 1,2,3-benzotriazole

MC1R signaling through the cAMP-CREB/ATF-1 and ERK-NFκB pathways accelerates G1/S transition promoting breast cancer progression

The ERK1/2 pathway modulates nuclear PTEN-mediated cell cycle arrest by cyclin D1 transcriptional regulation

Characterization of cryptic splicing in germline PTEN intronic variants in Cowden syndrome

PTEN interacts with RNA polymerase II to dephosphorylate polymerase II C-terminal domain

PTEN modulates gene transcription by redistributing genome-wide RNA polymerase II occupancy

Neural transcriptome of constitutional Pten dysfunction in mice and its relevance to human idiopathic autism spectrum disorder

Redefining the PTEN promoter: identification of novel upstream transcription start regions

CDK9 Inhibition by Dinaciclib Is a Therapeutic Vulnerability in Epithelioid Hemangioendothelioma

Germline disruption of Pten localization causes enhanced sex-dependent social motivation and increased glial production

Characterization of cryptic splicing in germline PTEN intronic variants in Cowden syndrome: CHEN et al

Germline EGFR mutation and cancer predisposition in adolescent and young adult (AYA) females with adrenocortical carcinoma

Activation of AR sensitizes breast carcinomas to NVP-BEZ235's therapeutic effect mediated by PTEN and KLLN upregulation

Germline compound heterozygous poly-glutamine deletion in USF3 may be involved in predisposition to heritable and sporadic epithelial thyroid carcinoma

Exome Sequencing Reveals Germline SMAD9 Mutation That Reduces Phosphatase and Tensin Homolog Expression and Is Associated With Hamartomatous Polyposis and Gastrointestinal Ganglioneuromas

Disruption of transforming growth factor-beta signaling by five frequently methylated genes leads to head and neck squamous cell carcinoma pathogenesis

Germline mutations in MSR1, ASCC1, and CTHRC1 in patients with Barrett esophagus and esophageal adenocarcinoma

1. Germline EGFR variants over-represented in adolescent and young adult (AYA) females with adrenocortical carcinoma

AP-2alpha induces epigenetic silencing of tumor suppressive genes and microsatellite instability in head and neck squamous cell carcinoma

Cowden Syndrome-Related Mutations in PTEN Associate with Enhanced Proteasome Activity

PTEN Lipid Phosphatase Activity and Proper Subcellular Localization Are Necessary and Sufficient for Down-Regulating AKT Phosphorylation in the Nucleus in Cowden Syndrome

Cytoplasm-predominant Pten associates with increased region-specific brain tyrosine hydroxylase and dopamine D2 receptors in mouse model with autistic traits

Utility of PTEN Protein Dosage in Predicting for Underlying Germline PTEN Mutations among Patients Presenting with Thyroid Cancer and Cowden-Like Phenotypes

AP-2[alpha] Induces Epigenetic Silencing of Tumor Suppressive Genes and Microsatellite Instability in Head and Neck Squamous Cell Carcinoma

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