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The Expanded Genetic Alphabet

Angewandte Chemie (International ed.), 2015-10, Vol.54 (41), p.11930-11944

International ed. in English, 2015

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Expansion of the Genetic Alphabet: A Chemist’s Approach to Synthetic Biology

Accounts of chemical research, 2018-02, Vol.51 (2), p.394-403

2018

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A semisynthetic organism engineered for the stable expansion of the genetic alphabet

Proceedings of the National Academy of Sciences - PNAS, 2017-02, Vol.114 (6), p.1317-1322

2017

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Polymerase Chain Transcription: Exponential Synthesis of RNA and Modified RNA

Journal of the American Chemical Society, 2017-07, Vol.139 (29), p.9949-9954

2017

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Reprograming the Replisome of a Semisynthetic Organism for the Expansion of the Genetic Alphabet

Journal of the American Chemical Society, 2018-01, Vol.140 (2), p.758-765

2018

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New codons for efficient production of unnatural proteins in a semisynthetic organism

Nature chemical biology, 2020-05, Vol.16 (5), p.570

2020

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In Vivo Structure–Activity Relationships and Optimization of an Unnatural Base Pair for Replication in a Semi-Synthetic Organism

Journal of the American Chemical Society, 2017-08, Vol.139 (33), p.11427-11433

2017

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Expansion of the genetic code via expansion of the genetic alphabet

Current opinion in chemical biology, 2018-10, Vol.46, p.196-202

2018

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Evolved polymerases facilitate selection of fully 2'-OMe-modified aptamers

Chemical science (Cambridge), 2017, Vol.8 (12), p.8179-8182

2017

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Progress toward Eukaryotic Semisynthetic Organisms: Translation of Unnatural Codons

Journal of the American Chemical Society, 2019-12, Vol.141 (51), p.20166-20170

2019

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Natural-like Replication of an Unnatural Base Pair for the Expansion of the Genetic Alphabet and Biotechnology Applications

Journal of the American Chemical Society, 2014-01, Vol.136 (3), p.826-829

2014

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Optimization of Replication, Transcription, and Translation in a Semi-Synthetic Organism

Journal of the American Chemical Society, 2019-07, Vol.141 (27), p.10644-10653

2019

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Transcription and Reverse Transcription of an Expanded Genetic Alphabet In Vitro and in a Semisynthetic Organism

Journal of the American Chemical Society, 2020-11, Vol.142 (45), p.19029-19032

2020

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Systematic exploration of a class of hydrophobic unnatural base pairs yields multiple new candidates for the expansion of the genetic alphabet

Nucleic acids research, 2014-09, Vol.42 (16), p.10235

2014

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Combating bacteria and drug resistance by inhibiting mechanisms of persistence and adaptation

Nature chemical biology, 2007-09, Vol.3 (9), p.549-556

2007

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Efficient and sequence-independent replication of DNA containing a third base pair establishes a functional six-letter genetic alphabet

Proceedings of the National Academy of Sciences - PNAS, 2012-07, Vol.109 (30), p.12005-12010

2012

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Transcription of an Expanded Genetic Alphabet

Journal of the American Chemical Society, 2009-04, Vol.131 (14), p.5046-5047

2009

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Genetic Code Expansion: Inception, Development, Commercialization

Journal of the American Chemical Society, 2021-04, Vol.143 (13), p.4859-4878

2021

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Discovery, implications and initial use of semi-synthetic organisms with an expanded genetic alphabet/code

Philosophical transactions of the Royal Society of London. Series B. Biological sciences, 2023-02, Vol.378 (1871), p.20220030

Romesberg, Floyd E

2023

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Creation, Optimization, and Use of Semi-Synthetic Organisms that Store and Retrieve Increased Genetic Information

Journal of molecular biology, 2022-04, Vol.434 (8), p.167331-167331, Article 167331

Romesberg, Floyd E.

2022

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Site-Specific Labeling of DNA and RNA Using an Efficiently Replicated and Transcribed Class of Unnatural Base Pairs

Journal of the American Chemical Society, 2011-12, Vol.133 (49), p.19878-19888

2011

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Optimization of an Unnatural Base Pair toward Natural-Like Replication

Journal of the American Chemical Society, 2009-03, Vol.131 (9), p.3246-3252

2009

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Inhibition of mutation and combating the evolution of antibiotic resistance

PLoS biology, 2005-06, Vol.3 (6), p.e176-e176

2005

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Transparent Window Vibrational Probes for the Characterization of Proteins With High Structural and Temporal Resolution

Chemical reviews, 2017-02, Vol.117 (3), p.1927-1969

2017

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Discovery, Characterization, and Optimization of an Unnatural Base Pair for Expansion of the Genetic Alphabet

Journal of the American Chemical Society, 2008-02, Vol.130 (7), p.2336-2343

2008

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The Expanded Genetic Alphabet

Expansion of the Genetic Alphabet: A Chemist’s Approach to Synthetic Biology

A semisynthetic organism engineered for the stable expansion of the genetic alphabet

Polymerase Chain Transcription: Exponential Synthesis of RNA and Modified RNA

Reprograming the Replisome of a Semisynthetic Organism for the Expansion of the Genetic Alphabet

New codons for efficient production of unnatural proteins in a semisynthetic organism

In Vivo Structure–Activity Relationships and Optimization of an Unnatural Base Pair for Replication in a Semi-Synthetic Organism

Expansion of the genetic code via expansion of the genetic alphabet

Evolved polymerases facilitate selection of fully 2'-OMe-modified aptamers

Progress toward Eukaryotic Semisynthetic Organisms: Translation of Unnatural Codons

Natural-like Replication of an Unnatural Base Pair for the Expansion of the Genetic Alphabet and Biotechnology Applications

Optimization of Replication, Transcription, and Translation in a Semi-Synthetic Organism

Transcription and Reverse Transcription of an Expanded Genetic Alphabet In Vitro and in a Semisynthetic Organism

Systematic exploration of a class of hydrophobic unnatural base pairs yields multiple new candidates for the expansion of the genetic alphabet

Combating bacteria and drug resistance by inhibiting mechanisms of persistence and adaptation

Efficient and sequence-independent replication of DNA containing a third base pair establishes a functional six-letter genetic alphabet

Transcription of an Expanded Genetic Alphabet

Genetic Code Expansion: Inception, Development, Commercialization

Discovery, implications and initial use of semi-synthetic organisms with an expanded genetic alphabet/code

Creation, Optimization, and Use of Semi-Synthetic Organisms that Store and Retrieve Increased Genetic Information

Site-Specific Labeling of DNA and RNA Using an Efficiently Replicated and Transcribed Class of Unnatural Base Pairs

Optimization of an Unnatural Base Pair toward Natural-Like Replication

Inhibition of mutation and combating the evolution of antibiotic resistance

Transparent Window Vibrational Probes for the Characterization of Proteins With High Structural and Temporal Resolution

Discovery, Characterization, and Optimization of an Unnatural Base Pair for Expansion of the Genetic Alphabet

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