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IL-13-induced airway mucus production is attenuated by MAPK13 inhibition

The Journal of clinical investigation, 2012-12, Vol.122 (12), p.4555-4568

2012

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Mitogen-activated protein kinase-guided drug discovery for post-viral and related types of lung disease

European respiratory review, 2024-01, Vol.33 (171), p.230220

2024

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A potent MAPK13-14 inhibitor prevents airway inflammation and mucus production

American journal of physiology. Lung cellular and molecular physiology, 2023-12, Vol.325 (6), p.L726-L740

2023

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The crystal structure of phosphorylated MAPK13 reveals common structural features and differences in p38 MAPK family activation

Acta crystallographica. Section D, Biological crystallography., 2015-04, Vol.71 (4), p.790-799

2015

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Self-cleavage of Human CLCA1 Protein by a Novel Internal Metalloprotease Domain Controls Calcium-activated Chloride Channel Activation

The Journal of biological chemistry, 2012-12, Vol.287 (50), p.42138-42149

2012

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First comprehensive structural and biophysical analysis of MAPK13 inhibitors targeting DFG-in and DFG-out binding modes

Biochimica et biophysica acta, 2016-11, Vol.1860 (11), p.2335-2344

2016

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Epithelial-Immune Cell Interactions for Drug Discovery in Chronic Obstructive Pulmonary Disease

Annals of the American Thoracic Society, 2018-12, Vol.15 (Suppl 4), p.S260-S265

2018

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Synthesis of the Selective D2 Receptor Agonist PNU-95666E from d-Phenylalanine Using a Sequential Oxidative Cyclization Strategy

Journal of organic chemistry, 1997-09, Vol.62 (19), p.6582-6587

1997

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High-throughput screening normalized to biological response: application to antiviral drug discovery

Journal of biomolecular screening, 2014-01, Vol.19 (1), p.119-130

2014

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Substituted 4-aminopiperidines having high in vitro affinity and selectivity for the cloned human dopamine D4 receptor

European journal of pharmacology, 1997-03, Vol.322 (2-3), p.283-286

1997

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Model for the polyepoxide cyclization route to polyether antibiotics

Journal of the American Chemical Society, 1986-04, Vol.108 (8), p.2105-2106

1986

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Synthesis of optically active isoquinuclidines utilizing a diastereoselectivity control element

Journal of organic chemistry, 1986-06, Vol.51 (12), p.2332-2342

1986

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Asymmetric Synthesis of the C3α Fragment of 5,6-Dihydro-α-pyrone Nonpeptidic HIV-1 Protease Inhibitors

Journal of organic chemistry, 1999-06, Vol.64 (13), p.4980-4984

1999

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First comprehensive structural and biophysical analysis of MAPK13 inhibitors targeting DFG-in and DFG-out binding modes

Biochimica et biophysica acta. General subjects, 2016-11, Vol.1860 (11 PA)

2016

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Self-Cleavage of Human CLCA1 by its Novel Metalloprotease Domain Controls Calcium-Activated Chloride Channel Activation

Biophysical journal, 2013-01, Vol.104 (2), p.629a-629a

2013

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Synthesis of an Azasteroid Using an Acyl Iminium Ion-Initiated Tandem Cyclization

Journal of organic chemistry, 1996-10, Vol.61 (20), p.6974-6979

1996

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Orally active central dopamine and serotonin receptor ligands: 5-, 6-, 7-, and 8-[[(trifluoromethyl)sulfonyl]oxy]-2-(di-n-propylamino)tetralins and the formation of active metabolites in vivo

Journal of medicinal chemistry, 1993-10, Vol.36 (22), p.3409-3416

1993

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Novel 2-substituted tetrahydro-3H-benz[e]indolamines: highly potent and selective agonists acting at the 5-HT1A receptor as possible anxiolytics and antidepressants

Journal of medicinal chemistry, 1993-07, Vol.36 (15), p.2066-2074

1993

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Asymmetric Synthesis of the C3alpha Fragment of 5,6-Dihydro-alpha-pyrone Nonpeptidic HIV-1 Protease Inhibitors

Journal of organic chemistry, 1999-06, Vol.64 (13), p.4980-4984

1999

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Synthesis of the Selective D 2 Receptor Agonist PNU-95666E from d -Phenylalanine Using a Sequential Oxidative Cyclization Strategy

Journal of organic chemistry, 1997-09, Vol.62 (19), p.6582-6587

1997

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Oxidative cyclization of acyclic ureas with bis(trifluoroacetoxy)iodobenzene to generate N-substituted 2-benzimidazolinones

Tetrahedron letters, 1996-04, Vol.37 (14), p.2361-2364

1996

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Substituted 4-aminopiperidines having high in vitro affinity and selectivity for the cloned human dopamine D 4 receptor

European journal of pharmacology, 1997-03, Vol.322 (2), p.283-286

1997

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Tea and Atherosclerosis

Nature (London), 1967-12, Vol.216 (5119), p.1014-1016

1967

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Synthesis of metabolically stable arylpiperazine 5-HT1A receptor agonists

Bioorganic & medicinal chemistry letters, 1992-12, Vol.2 (12), p.1703-1706

1992

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An improved synthesis of the dopamine autoreceptor antagonist (+)- cis-8-methoxy-1-methyl-2-(dipropylamino)tetralin (AJ-76)

Bioorganic & medicinal chemistry letters, 1992-12, Vol.2 (12), p.1691-1692

1992

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IL-13-induced airway mucus production is attenuated by MAPK13 inhibition

Mitogen-activated protein kinase-guided drug discovery for post-viral and related types of lung disease

A potent MAPK13-14 inhibitor prevents airway inflammation and mucus production

The crystal structure of phosphorylated MAPK13 reveals common structural features and differences in p38 MAPK family activation

Self-cleavage of Human CLCA1 Protein by a Novel Internal Metalloprotease Domain Controls Calcium-activated Chloride Channel Activation

First comprehensive structural and biophysical analysis of MAPK13 inhibitors targeting DFG-in and DFG-out binding modes

Epithelial-Immune Cell Interactions for Drug Discovery in Chronic Obstructive Pulmonary Disease

Synthesis of the Selective D2 Receptor Agonist PNU-95666E from d-Phenylalanine Using a Sequential Oxidative Cyclization Strategy

High-throughput screening normalized to biological response: application to antiviral drug discovery

Substituted 4-aminopiperidines having high in vitro affinity and selectivity for the cloned human dopamine D4 receptor

Model for the polyepoxide cyclization route to polyether antibiotics

Synthesis of optically active isoquinuclidines utilizing a diastereoselectivity control element

Asymmetric Synthesis of the C3α Fragment of 5,6-Dihydro-α-pyrone Nonpeptidic HIV-1 Protease Inhibitors

First comprehensive structural and biophysical analysis of MAPK13 inhibitors targeting DFG-in and DFG-out binding modes

Self-Cleavage of Human CLCA1 by its Novel Metalloprotease Domain Controls Calcium-Activated Chloride Channel Activation

Synthesis of an Azasteroid Using an Acyl Iminium Ion-Initiated Tandem Cyclization

Orally active central dopamine and serotonin receptor ligands: 5-, 6-, 7-, and 8-[[(trifluoromethyl)sulfonyl]oxy]-2-(di-n-propylamino)tetralins and the formation of active metabolites in vivo

Novel 2-substituted tetrahydro-3H-benz[e]indolamines: highly potent and selective agonists acting at the 5-HT1A receptor as possible anxiolytics and antidepressants

Asymmetric Synthesis of the C3alpha Fragment of 5,6-Dihydro-alpha-pyrone Nonpeptidic HIV-1 Protease Inhibitors

Synthesis of the Selective D 2 Receptor Agonist PNU-95666E from d -Phenylalanine Using a Sequential Oxidative Cyclization Strategy

Oxidative cyclization of acyclic ureas with bis(trifluoroacetoxy)iodobenzene to generate N-substituted 2-benzimidazolinones

Substituted 4-aminopiperidines having high in vitro affinity and selectivity for the cloned human dopamine D 4 receptor

Tea and Atherosclerosis

Synthesis of metabolically stable arylpiperazine 5-HT1A receptor agonists

An improved synthesis of the dopamine autoreceptor antagonist (+)- cis-8-methoxy-1-methyl-2-(dipropylamino)tetralin (AJ-76)

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