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Sestrin 2 and AMPK Connect Hyperglycemia to Nox4-Dependent Endothelial Nitric Oxide Synthase Uncoupling and Matrix Protein Expression

Molecular and Cellular Biology, 2013-09, Vol.33 (17), p.3439-3460

2013

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Oxidative stress induces phosphorylation of neuronal NOS in cardiomyocytes through AMP-activated protein kinase (AMPK)

Biochemical and biophysical research communications, 2015-04, Vol.459 (3), p.393-397

2015

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Neuronal nitric oxide synthase mediates insulin- and oxidative stress-induced glucose uptake in skeletal muscle myotubes

Free radical biology & medicine, 2017-09, Vol.110, p.261-269

2017

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Hydrophilic, Potent, and Selective 7‑Substituted 2‑Aminoquinolines as Improved Human Neuronal Nitric Oxide Synthase Inhibitors

Journal of medicinal chemistry, 2017-08, Vol.60 (16), p.7146-7165

2017

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Neuronal nitric oxide synthase is phosphorylated in response to insulin stimulation in skeletal muscle

Biochemical and biophysical research communications, 2013-06, Vol.435 (3), p.501-505

2013

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Minimal Pharmacophoric Elements and Fragment Hopping, an Approach Directed at Molecular Diversity and Isozyme Selectivity. Design of Selective Neuronal Nitric Oxide Synthase Inhibitors

Journal of the American Chemical Society, 2008-03, Vol.130 (12), p.3900-3914

2008

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Discovery of Highly Potent and Selective Inhibitors of Neuronal Nitric Oxide Synthase by Fragment Hopping

Journal of medicinal chemistry, 2009-02, Vol.52 (3), p.779-797

2009

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Electron Transfer by Neuronal Nitric-oxide Synthase Is Regulated by Concerted Interaction of Calmodulin and Two Intrinsic Regulatory Elements

The Journal of biological chemistry, 2006-08, Vol.281 (32), p.23111-23118

2006

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Conditional deletion of cytochrome p450 reductase in osteoprogenitor cells affects long bone and skull development in mice recapitulating antley-bixler syndrome: role of a redox enzyme in development

PloS one, 2013-09, Vol.8 (9), p.e75638

2013

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Differential calmodulin-modulatory and electron transfer properties of neuronal nitric oxide synthase mu compared to the alpha variant

FEBS letters, 2013-12, Vol.587 (24), p.3973-3978

2013

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Selective Monocationic Inhibitors of Neuronal Nitric Oxide Synthase. Binding Mode Insights from Molecular Dynamics Simulations

Journal of the American Chemical Society, 2012-07, Vol.134 (28), p.11559-11572

2012

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Design of Light-Sensitive Triggers for Endothelial NO-Synthase Activation

Antioxidants, 2020-02, Vol.9 (2), p.89

2020

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Nox4 NADPH oxidase mediates peroxynitrite-dependent uncoupling of endothelial nitric-oxide synthase and fibronectin expression in response to angiotensin II: role of mitochondrial reactive oxygen species

The Journal of biological chemistry, 2013-10, Vol.288 (40), p.28668-28686

2013

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Oxygen Metabolism by Endothelial Nitric-oxide Synthase

The Journal of biological chemistry, 2007-09, Vol.282 (39), p.28557-28565

2007

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The Role of Tetrahydrobiopterin in the Regulation of Neuronal Nitric-oxide Synthase-generated Superoxide

The Journal of biological chemistry, 2002-10, Vol.277 (43), p.40275-40280

2002

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Deciphering the binding of caveolin-1 to client protein endothelial nitric-oxide synthase (eNOS): scaffolding subdomain identification, interaction modeling, and biological significance

The Journal of biological chemistry, 2014-05, Vol.289 (19), p.13273-13283

2014

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Oxygen Metabolism by Neuronal Nitric-oxide Synthase

The Journal of biological chemistry, 2007-03, Vol.282 (11), p.7921-7929

2007

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Thermodynamics of Oxidation-Reduction Reactions in Mammalian Nitric-oxide Synthase Isoforms

The Journal of biological chemistry, 2004-04, Vol.279 (18), p.18759-18766

2004

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Generation and characterization of functional phosphoserine-incorporated neuronal nitric oxide synthase holoenzyme

Journal of biological inorganic chemistry, 2019-02, Vol.24 (1), p.1-9

2019

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Holoenzyme structures of endothelial nitric oxide synthase – An allosteric role for calmodulin in pivoting the FMN domain for electron transfer

Journal of structural biology, 2014-10, Vol.188 (1), p.46-54

2014

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Simplified 2‑Aminoquinoline-Based Scaffold for Potent and Selective Neuronal Nitric Oxide Synthase Inhibition

Journal of medicinal chemistry, 2014-02, Vol.57 (4), p.1513-1530

2014

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Deciphering the Binding of Caveolin-1 to Client Protein Endothelial Nitric-oxide Synthase (eNOS)

The Journal of biological chemistry, 2014-05, Vol.289 (19), p.13273-13283

2014

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Phenyl Ether- and Aniline-Containing 2‑Aminoquinolines as Potent and Selective Inhibitors of Neuronal Nitric Oxide Synthase

Journal of medicinal chemistry, 2015-11, Vol.58 (21), p.8694-8712

2015

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Potent and Selective Human Neuronal Nitric Oxide Synthase Inhibition by Optimization of the 2‑Aminopyridine-Based Scaffold with a Pyridine Linker

Journal of medicinal chemistry, 2016-05, Vol.59 (10), p.4913-4925

2016

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Potent and Selective Double-Headed Thiophene-2-carboximidamide Inhibitors of Neuronal Nitric Oxide Synthase for the Treatment of Melanoma

Journal of medicinal chemistry, 2014-02, Vol.57 (3), p.686-700

2014

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Sestrin 2 and AMPK Connect Hyperglycemia to Nox4-Dependent Endothelial Nitric Oxide Synthase Uncoupling and Matrix Protein Expression

Oxidative stress induces phosphorylation of neuronal NOS in cardiomyocytes through AMP-activated protein kinase (AMPK)

Neuronal nitric oxide synthase mediates insulin- and oxidative stress-induced glucose uptake in skeletal muscle myotubes

Hydrophilic, Potent, and Selective 7‑Substituted 2‑Aminoquinolines as Improved Human Neuronal Nitric Oxide Synthase Inhibitors

Neuronal nitric oxide synthase is phosphorylated in response to insulin stimulation in skeletal muscle

Minimal Pharmacophoric Elements and Fragment Hopping, an Approach Directed at Molecular Diversity and Isozyme Selectivity. Design of Selective Neuronal Nitric Oxide Synthase Inhibitors

Discovery of Highly Potent and Selective Inhibitors of Neuronal Nitric Oxide Synthase by Fragment Hopping

Electron Transfer by Neuronal Nitric-oxide Synthase Is Regulated by Concerted Interaction of Calmodulin and Two Intrinsic Regulatory Elements

Conditional deletion of cytochrome p450 reductase in osteoprogenitor cells affects long bone and skull development in mice recapitulating antley-bixler syndrome: role of a redox enzyme in development

Differential calmodulin-modulatory and electron transfer properties of neuronal nitric oxide synthase mu compared to the alpha variant

Selective Monocationic Inhibitors of Neuronal Nitric Oxide Synthase. Binding Mode Insights from Molecular Dynamics Simulations

Design of Light-Sensitive Triggers for Endothelial NO-Synthase Activation

Nox4 NADPH oxidase mediates peroxynitrite-dependent uncoupling of endothelial nitric-oxide synthase and fibronectin expression in response to angiotensin II: role of mitochondrial reactive oxygen species

Oxygen Metabolism by Endothelial Nitric-oxide Synthase

The Role of Tetrahydrobiopterin in the Regulation of Neuronal Nitric-oxide Synthase-generated Superoxide

Deciphering the binding of caveolin-1 to client protein endothelial nitric-oxide synthase (eNOS): scaffolding subdomain identification, interaction modeling, and biological significance

Oxygen Metabolism by Neuronal Nitric-oxide Synthase

Thermodynamics of Oxidation-Reduction Reactions in Mammalian Nitric-oxide Synthase Isoforms

Generation and characterization of functional phosphoserine-incorporated neuronal nitric oxide synthase holoenzyme

Holoenzyme structures of endothelial nitric oxide synthase – An allosteric role for calmodulin in pivoting the FMN domain for electron transfer

Simplified 2‑Aminoquinoline-Based Scaffold for Potent and Selective Neuronal Nitric Oxide Synthase Inhibition

Deciphering the Binding of Caveolin-1 to Client Protein Endothelial Nitric-oxide Synthase (eNOS)

Phenyl Ether- and Aniline-Containing 2‑Aminoquinolines as Potent and Selective Inhibitors of Neuronal Nitric Oxide Synthase

Potent and Selective Human Neuronal Nitric Oxide Synthase Inhibition by Optimization of the 2‑Aminopyridine-Based Scaffold with a Pyridine Linker

Potent and Selective Double-Headed Thiophene-2-carboximidamide Inhibitors of Neuronal Nitric Oxide Synthase for the Treatment of Melanoma

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