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Synergistic Effects of A Combined Treatment of Glioblastoma U251 Cells with An Anti-miR-10b-5p Molecule and An AntiCancer Agent Based on 1-(3′,4′,5′-Trimethoxyphenyl)-2-Aryl-1H-Imidazole Scaffold

International journal of molecular sciences, 2022-06, Vol.23 (11), p.5991

2022

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Apoptosis Pathways Triggered by a Potent Antiproliferative Hybrid Chalcone on Human Melanoma Cells

International journal of molecular sciences, 2021-12, Vol.22 (24), p.13462

2021

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Design, synthesis, and biological investigation of selective human carbonic anhydrase II, IX, and XII inhibitors using 7-aryl/heteroaryl triazolopyrimidines bearing a sulfanilamide scaffold

Journal of enzyme inhibition and medicinal chemistry, 2023-12, Vol.38 (1), p.2270180-2270180

2023

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Synthesis and Biological Evaluation of New Antitubulin Agents Containing 2-(3',4',5'-trimethoxyanilino)-3,6-disubstituted-4,5,6,7-tetrahydrothieno[2,3- c ]pyridine Scaffold

Molecules (Basel, Switzerland), 2020-04, Vol.25 (7), p.1690

2020

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Structural and Conformational Requisites in DNA Quadruplex Groove Binding: Another Piece to the Puzzle

Journal of the American Chemical Society, 2010-05, Vol.132 (18), p.6425-6433

2010

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Concise Synthesis and Biological Evaluation of 2‑Aroyl-5-Amino Benzo[b]thiophene Derivatives As a Novel Class of Potent Antimitotic Agents

Journal of medicinal chemistry, 2013-11, Vol.56 (22), p.9296-9309

2013

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DNA minor groove binders as potential antitumor and antimicrobial agents

Medicinal research reviews, 2004-07, Vol.24 (4), p.475-528

2004

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Synthesis and Biological Evaluation of 2-Substituted Benzyl-/Phenylethylamino-4-amino-5-aroylthiazoles as Apoptosis-Inducing Anticancer Agents

Molecules (Basel, Switzerland), 2020-05, Vol.25 (9), p.2177

2020

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Design, Synthesis and Biological Investigation of 2-Anilino Triazolopyrimidines as Tubulin Polymerization Inhibitors with Anticancer Activities

Pharmaceuticals (Basel, Switzerland), 2022-08, Vol.15 (8), p.1031

2022

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Synthesis and Biological Evaluation of Highly Active 7-Anilino Triazolopyrimidines as Potent Antimicrotubule Agents

Pharmaceutics, 2022-06, Vol.14 (6), p.1191

2022

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Design, synthesis and biological evaluation of 3,5-disubstituted 2-amino thiophene derivatives as a novel class of antitumor agents

Bioorganic & medicinal chemistry, 2014-09, Vol.22 (18), p.5097-5109

2014

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Synthesis and Biological Evaluation of 2- and 3-Aminobenzo[b]thiophene Derivatives as Antimitotic Agents and Inhibitors of Tubulin Polymerization

Journal of medicinal chemistry, 2007-05, Vol.50 (9), p.2273-2277

2007

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The Detrimental Action of Adenosine on Glutamate-Induced Cytotoxicity in PC12 Cells Can Be Shifted towards a Neuroprotective Role through A1AR Positive Allosteric Modulation

Cells (Basel, Switzerland), 2020-05, Vol.9 (5), p.1242

2020

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Design, synthesis, in vitro antiproliferative activity and apoptosis-inducing studies of 1-(3′,4′,5′-trimethoxyphenyl)-3-(2′-alkoxycarbonylindolyl)-2-propen-1-one derivatives obtained by a molecular hybridisation approach

Journal of enzyme inhibition and medicinal chemistry, 2018-01, Vol.33 (1), p.1225-1238

2018

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Design, synthesis and structure–activity relationship of 2-(3′,4′,5′-trimethoxybenzoyl)-benzo[ b]furan derivatives as a novel class of inhibitors of tubulin polymerization

Bioorganic & medicinal chemistry, 2009-10, Vol.17 (19), p.6862-6871

2009

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Synthesis and biological evaluation of alpha-bromoacryloylamido indolyl pyridinyl propenones as potent apoptotic inducers in human leukaemia cells

Journal of enzyme inhibition and medicinal chemistry, 2018-01, Vol.33 (1), p.727-742

2018

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Synthesis and Biological Evaluation of 1-Methyl-2-(3′,4′,5′-trimethoxybenzoyl)-3-aminoindoles as a New Class of Antimitotic Agents and Tubulin Inhibitors

Journal of medicinal chemistry, 2008-03, Vol.51 (5), p.1464-1468

2008

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Allosteric modulation of A1-adenosine receptor: a review

Drug discovery today. Technologies, 2013, Vol.10 (2), p.e285-e296

2013

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One-pot synthesis and biological evaluation of 2-pyrrolidinyl-4-amino-5-(3′,4′,5′-trimethoxybenzoyl)thiazole: A unique, highly active antimicrotubule agent

European journal of medicinal chemistry, 2011-12, Vol.46 (12), p.6015-6024

2011

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Agonists and antagonists acting at P2X7 receptor

Current topics in medicinal chemistry, 2004, Vol.4 (16), p.1707

2004

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[3H]MRE 3008F20: A Novel Antagonist Radioligand for the Pharmacological and Biochemical Characterization of Human A3 Adenosine Receptors

Molecular pharmacology, 2000-05, Vol.57 (5), p.968

2000

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Design, synthesis and antiproliferative activity of novel heterobivalent hybrids based on imidazo[2,1-b][1,3,4]thiadiazole and imidazo[2,1-b][1,3]thiazole scaffolds

European journal of medicinal chemistry, 2015-08, Vol.101, p.205-217

2015

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alpha-halogenoacrylic derivatives of antitumor agents

Mini reviews in medicinal chemistry, 2009-01, Vol.9 (1), p.81

2009

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Synthesis and Biological Evaluation of Pyrazolo[3,4-b]pyridin-4-ones as a New Class of Topoisomerase II Inhibitors

Medicinal chemistry (Shp-sariqah, United Arab Emirates), 2015-01, Vol.11 (4), p.342

2015

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Synergistic effects of the combined treatment of U251 and T98G glioma cells with an anti‑tubulin tetrahydrothieno[2,3‑c]pyridine derivative and a peptide nucleic acid targeting miR‑221‑3p

International journal of oncology, 2021-08, Vol.59 (2), p.1, Article 61

2021

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Synergistic Effects of A Combined Treatment of Glioblastoma U251 Cells with An Anti-miR-10b-5p Molecule and An AntiCancer Agent Based on 1-(3′,4′,5′-Trimethoxyphenyl)-2-Aryl-1H-Imidazole Scaffold

Apoptosis Pathways Triggered by a Potent Antiproliferative Hybrid Chalcone on Human Melanoma Cells

Design, synthesis, and biological investigation of selective human carbonic anhydrase II, IX, and XII inhibitors using 7-aryl/heteroaryl triazolopyrimidines bearing a sulfanilamide scaffold

Synthesis and Biological Evaluation of New Antitubulin Agents Containing 2-(3',4',5'-trimethoxyanilino)-3,6-disubstituted-4,5,6,7-tetrahydrothieno[2,3- c ]pyridine Scaffold

Structural and Conformational Requisites in DNA Quadruplex Groove Binding: Another Piece to the Puzzle

Concise Synthesis and Biological Evaluation of 2‑Aroyl-5-Amino Benzo[b]thiophene Derivatives As a Novel Class of Potent Antimitotic Agents

DNA minor groove binders as potential antitumor and antimicrobial agents

Synthesis and Biological Evaluation of 2-Substituted Benzyl-/Phenylethylamino-4-amino-5-aroylthiazoles as Apoptosis-Inducing Anticancer Agents

Design, Synthesis and Biological Investigation of 2-Anilino Triazolopyrimidines as Tubulin Polymerization Inhibitors with Anticancer Activities

Synthesis and Biological Evaluation of Highly Active 7-Anilino Triazolopyrimidines as Potent Antimicrotubule Agents

Design, synthesis and biological evaluation of 3,5-disubstituted 2-amino thiophene derivatives as a novel class of antitumor agents

Synthesis and Biological Evaluation of 2- and 3-Aminobenzo[b]thiophene Derivatives as Antimitotic Agents and Inhibitors of Tubulin Polymerization

The Detrimental Action of Adenosine on Glutamate-Induced Cytotoxicity in PC12 Cells Can Be Shifted towards a Neuroprotective Role through A1AR Positive Allosteric Modulation

Design, synthesis, in vitro antiproliferative activity and apoptosis-inducing studies of 1-(3′,4′,5′-trimethoxyphenyl)-3-(2′-alkoxycarbonylindolyl)-2-propen-1-one derivatives obtained by a molecular hybridisation approach

Design, synthesis and structure–activity relationship of 2-(3′,4′,5′-trimethoxybenzoyl)-benzo[ b]furan derivatives as a novel class of inhibitors of tubulin polymerization

Synthesis and biological evaluation of alpha-bromoacryloylamido indolyl pyridinyl propenones as potent apoptotic inducers in human leukaemia cells

Synthesis and Biological Evaluation of 1-Methyl-2-(3′,4′,5′-trimethoxybenzoyl)-3-aminoindoles as a New Class of Antimitotic Agents and Tubulin Inhibitors

Allosteric modulation of A1-adenosine receptor: a review

One-pot synthesis and biological evaluation of 2-pyrrolidinyl-4-amino-5-(3′,4′,5′-trimethoxybenzoyl)thiazole: A unique, highly active antimicrotubule agent

Agonists and antagonists acting at P2X7 receptor

[3H]MRE 3008F20: A Novel Antagonist Radioligand for the Pharmacological and Biochemical Characterization of Human A3 Adenosine Receptors

Design, synthesis and antiproliferative activity of novel heterobivalent hybrids based on imidazo[2,1-b][1,3,4]thiadiazole and imidazo[2,1-b][1,3]thiazole scaffolds

alpha-halogenoacrylic derivatives of antitumor agents

Synthesis and Biological Evaluation of Pyrazolo[3,4-b]pyridin-4-ones as a New Class of Topoisomerase II Inhibitors

Synergistic effects of the combined treatment of U251 and T98G glioma cells with an anti‑tubulin tetrahydrothieno[2,3‑c]pyridine derivative and a peptide nucleic acid targeting miR‑221‑3p

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