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PARP1-SNAI2 transcription axis drives resistance to PARP inhibitor, Talazoparib

Scientific reports, 2022-07, Vol.12 (1), p.12501-12501, Article 12501

2022

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Large-scale structure of genomic methylation patterns

Genome Research, 2006-02, Vol.16 (2), p.157-163

2006

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Drosophila Nipped-B Protein Supports Sister Chromatid Cohesion and Opposes the Stromalin/Scc3 Cohesion Factor To Facilitate Long-Range Activation of the cut Gene

Molecular and Cellular Biology, 2004-04, Vol.24 (8), p.3100-3111

2004

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Computational Prediction of Methylation Status in Human Genomic Sequences

Proceedings of the National Academy of Sciences - PNAS, 2006-07, Vol.103 (28), p.10713-10716

2006

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Nipped-B, a Drosophila Homologue of Chromosomal Adherins, Participates in Activation by Remote Enhancers in the cut and Ultrabithorax Genes

Genetics (Austin), 1999-06, Vol.152 (2), p.577-593

1999

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Metazoan Scc4 homologs link sister chromatid cohesion to cell and axon migration guidance

PLoS biology, 2006-08, Vol.4 (8), p.e242-e242

2006

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Optimization of Orally Bioavailable Enhancer of Zeste Homolog 2 (EZH2) Inhibitors Using Ligand and Property-Based Design Strategies: Identification of Development Candidate (R)-5,8-Dichloro-7-(methoxy(oxetan-3-yl)methyl)-2-((4-methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-3,4-dihydroisoquinolin-1(2H)-one (PF-06821497)

Journal of medicinal chemistry, 2018-02, Vol.61 (3), p.650-665

2018

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The complex role of EZH2 in the tumor microenvironment: opportunities and challenges for immunotherapy combinations

Future medicinal chemistry, 2020-08, Vol.12 (15), p.1415-1430

2020

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Cooperation Between Distinct Cancer Driver Genes Underlies Intertumor Heterogeneity in Hepatocellular Carcinoma

Gastroenterology (New York, N.Y. 1943), 2020-12, Vol.159 (6), p.2203-2220.e14

2020

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Functional links between Drosophila Nipped-B and cohesin in somatic and meiotic cells

Chromosoma, 2008-02, Vol.117 (1), p.51-66

2008

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Chromatin and sequence features that define the fine and gross structure of genomic methylation patterns

Genome research, 2010-07, Vol.20 (7), p.972-980

2010

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Reciprocal regulation of amino acid import and epigenetic state through Lat1 and EZH2

The EMBO journal, 2015-07, Vol.34 (13), p.1773-1785

2015

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Epigenetic reprogramming by tumor-derived EZH2 gain-of-function mutations promotes aggressive 3D cell morphologies and enhances melanoma tumor growth

Oncotarget, 2015-02, Vol.6 (5), p.2928-2938

2015

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Epigenetic reprogramming in solid tumors: therapeutic implications of EZH2 gain-of-function mutations

Epigenomics, 2015-08, Vol.7 (5), p.687-690

2015

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Methylation Abnormalities in Mammary Carcinoma: The Methylation Suicide Hypothesis

Journal of cancer therapy, 2014-12, Vol.5 (14), p.1311-1324

2014

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Cooperation between distinct cancer driver genes underlies inter-tumor heterogeneity in hepatocellular carcinoma

Gastroenterology (New York, N.Y. 1943), 2020-08, Vol.159 (6), p.2203-2220.e14

2020

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Epigenetic reprogramming in solid tumors: therapeutic implications of

Epigenomics, 2015-08, Vol.7 (5), p.687-690

2015

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Control of mammary tumor differentiation by SKI-606 (bosutinib)

Oncogene, 2011-01, Vol.30 (3), p.301-312

2011

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Reciprocal regulation of amino acid import and epigenetic state through Lat1 and EZH 2

The EMBO journal, 2015-07, Vol.34 (13), p.1773-1785

2015

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Abstract 5144: Epigenetic reprogramming by tumor-derived EZH2 gain of function mutants leads to aggressive 3D-cell morphologies in both epithelial and melanoma cells

Cancer research (Chicago, Ill.), 2014-10, Vol.74 (19_Supplement), p.5144-5144

2014

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Assessment of energy reserves by damselflies engaged in aerial contests for mating territories

Animal behaviour, 1994-11, Vol.48 (5), p.1023-1030

1994

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MIP1, a new yeast gene homologous to the rat mitochondrial intermediate peptidase gene, is required for oxidative metabolism in Saccharomyces cerevisiae

Molecular and Cellular Biology, 1994-08, Vol.14 (8), p.5603-5616

1994

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Design and Synthesis of Pyridone-Containing 3,4-Dihydroisoquinoline-1(2H)‑ones as a Novel Class of Enhancer of Zeste Homolog 2 (EZH2) Inhibitors

PARP1-SNAI2 transcription axis drives resistance to PARP inhibitor, Talazoparib

Large-scale structure of genomic methylation patterns

Drosophila Nipped-B Protein Supports Sister Chromatid Cohesion and Opposes the Stromalin/Scc3 Cohesion Factor To Facilitate Long-Range Activation of the cut Gene

Computational Prediction of Methylation Status in Human Genomic Sequences

Nipped-B, a Drosophila Homologue of Chromosomal Adherins, Participates in Activation by Remote Enhancers in the cut and Ultrabithorax Genes

Metazoan Scc4 homologs link sister chromatid cohesion to cell and axon migration guidance

The complex role of EZH2 in the tumor microenvironment: opportunities and challenges for immunotherapy combinations

Cooperation Between Distinct Cancer Driver Genes Underlies Intertumor Heterogeneity in Hepatocellular Carcinoma

Functional links between Drosophila Nipped-B and cohesin in somatic and meiotic cells

Chromatin and sequence features that define the fine and gross structure of genomic methylation patterns

Reciprocal regulation of amino acid import and epigenetic state through Lat1 and EZH2

Epigenetic reprogramming by tumor-derived EZH2 gain-of-function mutations promotes aggressive 3D cell morphologies and enhances melanoma tumor growth

Epigenetic reprogramming in solid tumors: therapeutic implications of EZH2 gain-of-function mutations

Correction to Design and Synthesis of Pyridone-Containing 3,4-Dihydroisoquinoline-1(2H)‑ones as a Novel Class of Enhancer of Zeste Homolog 2 (EZH2) Inhibitors

Analysis of seven SARS-CoV-2 rapid antigen tests in detecting omicron (B.1.1.529) versus delta (B.1.617.2) using cell culture supernatants and clinical specimens

Methylation Abnormalities in Mammary Carcinoma: The Methylation Suicide Hypothesis

Cooperation between distinct cancer driver genes underlies inter-tumor heterogeneity in hepatocellular carcinoma

Epigenetic reprogramming in solid tumors: therapeutic implications of

Control of mammary tumor differentiation by SKI-606 (bosutinib)

Reciprocal regulation of amino acid import and epigenetic state through Lat1 and EZH 2

Abstract 5144: Epigenetic reprogramming by tumor-derived EZH2 gain of function mutants leads to aggressive 3D-cell morphologies in both epithelial and melanoma cells

Assessment of energy reserves by damselflies engaged in aerial contests for mating territories

MIP1, a new yeast gene homologous to the rat mitochondrial intermediate peptidase gene, is required for oxidative metabolism in Saccharomyces cerevisiae

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