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Yeast and human P4-ATPases transport glycosphingolipids using conserved structural motifs

The Journal of biological chemistry, 2019-02, Vol.294 (6), p.1794-1806

2019

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Directed evolution of a sphingomyelin flippase reveals mechanism of substrate backbone discrimination by a P4-ATPase

Proceedings of the National Academy of Sciences - PNAS, 2016-08, Vol.113 (31), p.E4460-E4466

2016

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Adaptive substitutions underlying cardiac glycoside insensitivity in insects exhibit epistasis in vivo

eLife, 2019-08, Vol.8

2019

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Structural and Genetic Studies Demonstrate Neurologic Dysfunction in Triosephosphate Isomerase Deficiency Is Associated with Impaired Synaptic Vesicle Dynamics

PLoS genetics, 2016-03, Vol.12 (3), p.e1005941-e1005941

2016

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Exofacial membrane composition and lipid metabolism regulates plasma membrane P4-ATPase substrate specificity

The Journal of biological chemistry, 2020-12, Vol.295 (52), p.17997-18009

2020

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Impact of Updating Pharmacogenetic Results: Lessons Learned from the PREDICT Program

Journal of personalized medicine, 2021-10, Vol.11 (11), p.1051

2021

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Decoding P4-ATPase substrate interactions

Critical reviews in biochemistry and molecular biology, 2016-11, Vol.51 (6), p.513-527

2016

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A Tutorial for Pharmacogenomics Implementation Through End‐to‐End Clinical Decision Support Based on Ten Years of Experience from PREDICT

Clinical pharmacology and therapeutics, 2021-01, Vol.109 (1), p.101-115

2021

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Predatory fireflies and their toxic firefly prey have evolved distinct toxin resistance strategies

Current biology, 2023-12, Vol.33 (23), p.5160-5168.e7

2023

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Inhibiting the Nucleation of Amyloid Structure in a Huntingtin Fragment by Targeting α-Helix-Rich Oligomeric Intermediates

Journal of molecular biology, 2012-02, Vol.415 (5), p.900-917

2012

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Genetically engineered mesenchymal stem cells reduce behavioral deficits in the YAC 128 mouse model of Huntington's disease

Behavioural brain research, 2010-12, Vol.214 (2), p.193-200

2010

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A serendipitous survey of prediction algorithms for amyloidogenicity

Biopolymers, 2013-11, Vol.100 (6), p.780-789

2013

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Missense variant in TPI1 (Arg189Gln) causes neurologic deficits through structural changes in the triosephosphate isomerase catalytic site and reduced enzyme levels in vivo

Biochimica et biophysica acta. Molecular basis of disease, 2019-09, Vol.1865 (9), p.2257-2266

2019

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Triosephosphate isomerase I170V alters catalytic site, enhances stability and induces pathology in a Drosophila model of TPI deficiency

Biochimica et biophysica acta, 2015-01, Vol.1852 (1), p.61-69

2015

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Evidence of a triosephosphate isomerase non-catalytic function crucial to behavior and longevity

Journal of cell science, 2013-07, Vol.126 (Pt 14), p.3151-3158

2013

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Evidence of a triosephosphate isomerase non-catalytic function critical to behavior and longevity

Journal of cell science, 2013-01

2013

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Exofacial membrane composition and lipid metabolism regulates plasma membrane P4-ATPase substrate specificity

The Journal of biological chemistry, 2020-12, Vol.295 (52), p.17997

2020

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Structural and Genetic Studies Demonstrate Neurologic Dysfunction in Triosephosphate Isomerase Deficiency Is Associated with Impaired Synaptic Vesicle Dynamics

PLoS genetics, 2016-03, Vol.12 (3)

2016

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Triosephosphate isomerase I170V alters catalytic site, enhances stability and induces pathology in a Drosophila model of TPI deficiency

Biochimica et biophysica acta. Molecular basis of disease, 2014-10, Vol.1852 (1)

2014

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An in vivo structure-function analysis of the pathogenesis of triosephosphate isomerase deficiency

Roland, Bartholomew P

2014

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Development of a theory- and evidence-based intervention to enhance implementation of physical therapy guidelines for the management of low back pain

Archives of public health = Archives belges de santé publique, 2014-01, Vol.72 (1), p.1-1, Article 1

2014

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Water Ice on Triton

Icarus (New York, N.Y. 1962), 2000-09, Vol.147 (1), p.309-316

2000

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Characterization of highly purified, inactivated HIV-1 particles isolated by anion exchange chromatography

Vaccine, 1998-01, Vol.16 (2), p.119-129

1998

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Imidazo[1,2-c]pyrimidine nucleosides. Synthesis of N-bridgehead inosine monophosphate and guanosine monophosphate analogs related to 3-deazapurines

Journal of organic chemistry, 1975-12, Vol.40 (25), p.3708-3713

1975

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Yeast and human P4-ATPases transport glycosphingolipids using conserved structural motifs

Directed evolution of a sphingomyelin flippase reveals mechanism of substrate backbone discrimination by a P4-ATPase

Adaptive substitutions underlying cardiac glycoside insensitivity in insects exhibit epistasis in vivo

Structural and Genetic Studies Demonstrate Neurologic Dysfunction in Triosephosphate Isomerase Deficiency Is Associated with Impaired Synaptic Vesicle Dynamics

Exofacial membrane composition and lipid metabolism regulates plasma membrane P4-ATPase substrate specificity

Impact of Updating Pharmacogenetic Results: Lessons Learned from the PREDICT Program

Decoding P4-ATPase substrate interactions

A Tutorial for Pharmacogenomics Implementation Through End‐to‐End Clinical Decision Support Based on Ten Years of Experience from PREDICT

Predatory fireflies and their toxic firefly prey have evolved distinct toxin resistance strategies

Inhibiting the Nucleation of Amyloid Structure in a Huntingtin Fragment by Targeting α-Helix-Rich Oligomeric Intermediates

Genetically engineered mesenchymal stem cells reduce behavioral deficits in the YAC 128 mouse model of Huntington's disease

A serendipitous survey of prediction algorithms for amyloidogenicity

Missense variant in TPI1 (Arg189Gln) causes neurologic deficits through structural changes in the triosephosphate isomerase catalytic site and reduced enzyme levels in vivo

Triosephosphate isomerase I170V alters catalytic site, enhances stability and induces pathology in a Drosophila model of TPI deficiency

Evidence of a triosephosphate isomerase non-catalytic function crucial to behavior and longevity

Evidence of a triosephosphate isomerase non-catalytic function critical to behavior and longevity

Exofacial membrane composition and lipid metabolism regulates plasma membrane P4-ATPase substrate specificity

Structural and Genetic Studies Demonstrate Neurologic Dysfunction in Triosephosphate Isomerase Deficiency Is Associated with Impaired Synaptic Vesicle Dynamics

Triosephosphate isomerase I170V alters catalytic site, enhances stability and induces pathology in a Drosophila model of TPI deficiency

An in vivo structure-function analysis of the pathogenesis of triosephosphate isomerase deficiency

Development of a theory- and evidence-based intervention to enhance implementation of physical therapy guidelines for the management of low back pain

Water Ice on Triton

Characterization of highly purified, inactivated HIV-1 particles isolated by anion exchange chromatography

Imidazo[1,2-c]pyrimidine nucleosides. Synthesis of N-bridgehead inosine monophosphate and guanosine monophosphate analogs related to 3-deazapurines

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