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ADAMTS5 is the major aggrecanase in mouse cartilage in vivo and in vitro

Nature, 2005-03, Vol.434 (7033), p.648-652

2005

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ADAMTS-9 in Mouse Cartilage Has Aggrecanase Activity That Is Distinct from ADAMTS-4 and ADAMTS-5

International journal of molecular sciences, 2019-01, Vol.20 (3), p.573

2019

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Identification and characterization of a ligand‐selective mineralocorticoid receptor coactivator

The FASEB journal, 2014-10, Vol.28 (10), p.4200-4210

2014

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Effects of stimulated aggrecanolysis on nanoscale morphological and mechanical properties of wild-type and aggrecanase-resistant mutant mice cartilages

The European physical journal. E, Soft matter and biological physics, 2017-08, Vol.40 (8), p.72-7, Article 72

2017

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Structural and Functional Characterization of the Interdomain Interaction in the Mineralocorticoid Receptor

Molecular endocrinology (Baltimore, Md.), 2009-09, Vol.23 (9), p.1360-1370

2009

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ADAMTS-5 Deficiency Does Not Block Aggrecanolysis at Preferred Cleavage Sites in the Chondroitin Sulfate-rich Region of Aggrecan

The Journal of biological chemistry, 2007-03, Vol.282 (12), p.8632-8640

2007

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Interdomain interactions in the mineralocorticoid receptor

Molecular and cellular endocrinology, 2003-02, Vol.200 (1), p.45-55

2003

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Distinguishing Aggrecan Loss from Aggrecan Proteolysis in ADAMTS-4 and ADAMTS-5 Single and Double Deficient Mice

The Journal of biological chemistry, 2007-12, Vol.282 (52), p.37420-37428

2007

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Mineralocorticoid receptor binding, structure and function

Molecular and cellular endocrinology, 2004-03, Vol.217 (1), p.203-212

2004

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Investigating ADAMTS-mediated aggrecanolysis in mouse cartilage

Nature protocols, 2011-03, Vol.6 (3), p.388-404

2011

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Differences in the determinants of eplerenone, spironolactone and aldosterone binding to the mineralocorticoid receptor

Clinical and experimental pharmacology & physiology, 2004-10, Vol.31 (10), p.704-709

2004

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A Disintegrin and Metalloproteinase with Thrombospondin Motifs-5 (ADAMTS-5) Forms Catalytically Active Oligomers

The Journal of biological chemistry, 2016-02, Vol.291 (7), p.3197-3208

2016

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Human hypertension caused by mutations in the kidney isozyme of 11β-hydroxysteroid dehydrogenase

Nature genetics, 1995-08, Vol.10 (4), p.394-399

1995

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Cartilage matrix degradation: an appropriate therapeutic target in osteoarthritis

Therapy, 2010-11, Vol.7 (6), p.579-582

Rogerson, Fraser M

2010

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Erratum: Cytokine‐induced increases in ADAMTS‐4 messenger RNA expression do not lead to increased aggrecanase activity in ADAMTS‐5–deficient mice

Arthritis & rheumatology (Hoboken, N.J.), 2011-01, Vol.63 (1), p.256-256

2011

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Mineralocorticoid action

Steroids, 2000-02, Vol.65 (2), p.61-73

2000

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Cortisol resistance in the New World revisited

Trends in endocrinology and metabolism, 2004-09, Vol.15 (7), p.296-299

2004

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Structural Determinants of Aldosterone Binding Selectivity in the Mineralocorticoid Receptor

The Journal of biological chemistry, 1999-12, Vol.274 (51), p.36305-36311

1999

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Dissecting mineralocorticoid receptor structure and function

Journal of steroid biochemistry and molecular biology, 2003-06, Vol.85 (2), p.389-396

2003

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Presence of angiotensin converting enzyme in the adventitia of large blood vessels

Journal of hypertension, 1992-07, Vol.10 (7), p.615-620

1992

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Mutants of 11β-Hydroxysteroid Dehydrogenase (11-HSD2) With Partial Activity: Improved Correlations Between Genotype and Biochemical Phenotype in Apparent Mineralocorticoid Excess

Hypertension (Dallas, Tex. 1979), 1999-10, Vol.34 (4, Part 1), p.638-642

1999

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Evidence of a novel aggrecan‐degrading activity in cartilage: Studies of mice deficient in both ADAMTS‐4 and ADAMTS‐5

Arthritis and rheumatism, 2008-06, Vol.58 (6), p.1664-1673

2008

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Variation in placental type 2 11 β-hydroxysteroid dehydrogenase activity is not related to birth weight or placental weight

Molecular and cellular endocrinology, 1997-04, Vol.128 (1), p.103-109

1997

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Pseudohypoaldosteronism: kidney, lungs and colon

Clinical endocrinology (Oxford), 2002-05, Vol.56 (5), p.571-572

2002

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ADAMTS-5: the story so far

European Cells and Materials, 2008-02, Vol.15, p.11-26

2008

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ADAMTS5 is the major aggrecanase in mouse cartilage in vivo and in vitro

ADAMTS-9 in Mouse Cartilage Has Aggrecanase Activity That Is Distinct from ADAMTS-4 and ADAMTS-5

Identification and characterization of a ligand‐selective mineralocorticoid receptor coactivator

Effects of stimulated aggrecanolysis on nanoscale morphological and mechanical properties of wild-type and aggrecanase-resistant mutant mice cartilages

Structural and Functional Characterization of the Interdomain Interaction in the Mineralocorticoid Receptor

ADAMTS-5 Deficiency Does Not Block Aggrecanolysis at Preferred Cleavage Sites in the Chondroitin Sulfate-rich Region of Aggrecan

Interdomain interactions in the mineralocorticoid receptor

Distinguishing Aggrecan Loss from Aggrecan Proteolysis in ADAMTS-4 and ADAMTS-5 Single and Double Deficient Mice

Mineralocorticoid receptor binding, structure and function

Investigating ADAMTS-mediated aggrecanolysis in mouse cartilage

Differences in the determinants of eplerenone, spironolactone and aldosterone binding to the mineralocorticoid receptor

A Disintegrin and Metalloproteinase with Thrombospondin Motifs-5 (ADAMTS-5) Forms Catalytically Active Oligomers

Human hypertension caused by mutations in the kidney isozyme of 11β-hydroxysteroid dehydrogenase

Cartilage matrix degradation: an appropriate therapeutic target in osteoarthritis

Erratum: Cytokine‐induced increases in ADAMTS‐4 messenger RNA expression do not lead to increased aggrecanase activity in ADAMTS‐5–deficient mice

Mineralocorticoid action

Cortisol resistance in the New World revisited

Structural Determinants of Aldosterone Binding Selectivity in the Mineralocorticoid Receptor

Dissecting mineralocorticoid receptor structure and function

Presence of angiotensin converting enzyme in the adventitia of large blood vessels

Mutants of 11β-Hydroxysteroid Dehydrogenase (11-HSD2) With Partial Activity: Improved Correlations Between Genotype and Biochemical Phenotype in Apparent Mineralocorticoid Excess

Evidence of a novel aggrecan‐degrading activity in cartilage: Studies of mice deficient in both ADAMTS‐4 and ADAMTS‐5

Variation in placental type 2 11 β-hydroxysteroid dehydrogenase activity is not related to birth weight or placental weight

Pseudohypoaldosteronism: kidney, lungs and colon

ADAMTS-5: the story so far

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