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Effects of sclerostin antibodies in animal models of osteoporosis
Bone (New York, N.Y.), 2017-03, Vol.96, p.63-75
2017
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Choice of Morphometric Methods and Consequences in the Regulatory Environment
Toxicologic Pathology, 2010-12, Vol.38 (7), p.1128-1133
2010
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Kinetic reconstruction reveals time-dependent effects of romosozumab on bone formation and osteoblast function in vertebral cancellous and cortical bone in cynomolgus monkeys
Bone (New York, N.Y.), 2017-08, Vol.101, p.77-87
2017
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Society of Toxicologic Pathology Position Paper: Review Series: Assessment of Circulating Hormones in Nonclinical Toxicity Studies: General Concepts and Considerations
Toxicologic pathology, 2012-08, Vol.40 (6), p.943-950
2012
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Nonproliferative and Proliferative Lesions of the Rat and Mouse Skeletal Tissues (Bones, Joints, and Teeth)
Journal of Toxicologic Pathology, 2016, Vol.29(3_Suppl), pp.49S-103S
2016
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Design-based Stereology: Introduction to Basic Concepts and Practical Approaches for Estimation of Cell Number
Toxicologic Pathology, 2010-12, Vol.38 (7), p.1011-1025
2010
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Differential temporal effects of sclerostin antibody and parathyroid hormone on cancellous and cortical bone and quantitative differences in effects on the osteoblast lineage in young intact rats
Bone (New York, N.Y.), 2015-12, Vol.81, p.380-391
2015
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Carcinogenicity risk assessment of romosozumab: A review of scientific weight-of-evidence and findings in a rat lifetime pharmacology study
Regulatory toxicology and pharmacology, 2016-11, Vol.81, p.212-222
2016
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Decreased osteoprogenitor proliferation precedes attenuation of cancellous bone formation in ovariectomized rats treated with sclerostin antibody
Bone Reports, 2018-06, Vol.8, p.90-94
2018
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Differential time-dependent transcriptional changes in the osteoblast lineage in cortical bone associated with sclerostin antibody treatment in ovariectomized rats
Bone Reports, 2018-06, Vol.8, p.95-103
2018
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Recommendations for the Evaluation of Pathology Data in Nonclinical Safety Biomarker Qualification Studies
Toxicologic Pathology, 2011-12, Vol.39 (7), p.1129-1137
2011
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Inhibition of both sclerostin and DKK1 results in novel skull findings in the rat and non-human primate that is not observed with inhibition of sclerostin alone
Bone (New York, N.Y.), 2024-02, Vol.179, p.116985-116985, Article 116985
2024
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Topic of Histopathology Blinding in Nonclinical Safety Biomarker Qualification Studies
Toxicologic pathology, 2010-06, Vol.38 (4), p.666-667
2010
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Modeling‐Based Bone Formation After 2 Months of Romosozumab Treatment: Results From the FRAME Clinical Trial
Journal of bone and mineral research, 2022-01, Vol.37 (1), p.36-40
2022
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Based Bone Formation After 2 Months of Romosozumab Treatment: Results From the FRAME Clinical Trial
Journal of bone and mineral research, 2022
2022
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Modeling‐Based Bone Formation After 2Months of Romosozumab Treatment: Results From the FRAME Clinical Trial
Journal of bone and mineral research, 2022-01, Vol.37 (1), p.36-40
2022
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Transcriptional Profiling of Laser Capture Microdissected Subpopulations of the Osteoblast Lineage Provides Insight Into the Early Response to Sclerostin Antibody in Rats
Journal of bone and mineral research, 2015-08, Vol.30 (8), p.1457-1467
2015
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Time-dependent cellular and transcriptional changes in the osteoblast lineage associated with sclerostin antibody treatment in ovariectomized rats
Bone (New York, N.Y.), 2016-03, Vol.84, p.148-159
2016
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A Metric Fractionator for Estimation of Total Cell Number in Paraffin-Embedded Flat or Hollow Organs
Toxicologic pathology, 2020-08, Vol.48 (6), p.784-790
2020
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Nonclinical cardiovascular safety evaluation of romosozumab, an inhibitor of sclerostin for the treatment of osteoporosis in postmenopausal women at high risk of fracture
Regulatory toxicology and pharmacology, 2020-08, Vol.115, p.104697, Article 104697
2020
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Stereological Solutions for Common Quantitative Endpoints in Neurotoxicology
Fundamental Neuropathology for Pathologists and Toxicologists, 2011, p.209-228
2011
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Evaluation of the skeletal effects of combined mild dietary calcium restriction and ovariectomy in sinclair S‐1 minipigs: A pilot study
Journal of bone and mineral research, 1993-11, Vol.8 (11), p.1311-1321
1993
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Stereological Principles and Sampling Procedures for Toxicologic Pathologists
Haschek and Rousseaux's Handbook of Toxicologic Pathology, 2013, p.215-286
Third Edition, 2013
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Chapter 8 - Stereological Principles and Sampling Procedures for Toxicologic Pathologists
Haschek and Rousseaux’s Handbook of Toxicologic Pathology, 2013, p.215-286
Third Edition, 2013
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EFFECTS OF DIETARY CALCIUM AND UREMIA ON 1,25-DIHYDROXYCHOLECALCIFEROL - INDUCED BONE FORMATION
1982
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