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Polyethylene Glycol Immunogenicity: Theoretical, Clinical, and Practical Aspects of Anti-Polyethylene Glycol Antibodies

ACS nano, 2021-09, Vol.15 (9), p.14022-14048

2021

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CD44v6 Dependence of Premetastatic Niche Preparation by Exosomes

Neoplasia (New York, N.Y.), 2009-10, Vol.11 (10), p.1093,IN13-1105,IN17

2009

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Interactions between nanoparticle corona proteins and the immune system

Current opinion in biotechnology, 2023-12, Vol.84, p.103010-103010, Article 103010

2023

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Premature Drug Release from Polyethylene Glycol (PEG)-Coated Liposomal Doxorubicin via Formation of the Membrane Attack Complex

ACS nano, 2020-07, Vol.14 (7), p.7808-7822

2020

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Measurement of Pre-Existing IgG and IgM Antibodies against Polyethylene Glycol in Healthy Individuals

Analytical chemistry (Washington), 2016-11, Vol.88 (21), p.10661-10666

2016

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Conditional internalization of PEGylated nanomedicines by PEG engagers for triple negative breast cancer therapy

Nature communications, 2017-06, Vol.8 (1), p.15507-15507, Article 15507

2017

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Liposomes with Low Levels of Grafted Poly(ethylene glycol) Remain Susceptible to Destabilization by Anti-Poly(ethylene glycol) Antibodies

ACS nano, 2024-08, Vol.18 (33), p.22122-22138

2024

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Antibodies against Poly(ethylene glycol) Activate Innate Immune Cells and Induce Hypersensitivity Reactions to PEGylated Nanomedicines

ACS nano, 2023-03, Vol.17 (6), p.5757-5772

2023

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Display of GPI‐anchored anti‐EGFR nanobodies on extracellular vesicles promotes tumour cell targeting

Journal of extracellular vesicles, 2016-01, Vol.5 (1), p.31053-n/a

2016

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Accelerated clearance by antibodies against methoxy PEG depends on pegylation architecture

Journal of controlled release, 2023-02, Vol.354, p.354-367

2023

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Effect of Cellular Location of Human Carboxylesterase 2 on CPT-11 Hydrolysis and Anticancer Activity

PloS one, 2015-10, Vol.10 (10), p.e0141088-e0141088

2015

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The interplay between membrane topology and mechanical forces in regulating T cell receptor activity

Communications biology, 2022-01, Vol.5 (1), p.40-16, Article 40

2022

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A genome-wide association study identifies a novel susceptibility locus for the immunogenicity of polyethylene glycol

Nature communications, 2017-09, Vol.8 (1), p.522-7, Article 522

2017

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Glucuronides: From biological waste to bio-nanomedical applications

Journal of controlled release, 2022-09, Vol.349, p.765-782

2022

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Replacement of L-amino acid peptides with D-amino acid peptides mitigates anti-PEG antibody generation against polymer-peptide conjugates in mice

Journal of controlled release, 2021-03, Vol.331, p.142-153

2021

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Pre-existing anti-polyethylene glycol antibody reduces the therapeutic efficacy and pharmacokinetics of PEGylated liposomes

Theranostics, 2018-01, Vol.8 (11), p.3164-3175

2018

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Analytical Measurement of PEGylated Molecules

Bioconjugate chemistry, 2012-05, Vol.23 (5), p.881-899

2012

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Bispecific T-cell engagers non-covalently decorated drug-loaded PEGylated nanocarriers for cancer immunochemotherapy

Journal of controlled release, 2022-04, Vol.344, p.235-248

2022

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Inhibition of gut microbial β-glucuronidase effectively prevents carcinogen-induced microbial dysbiosis and intestinal tumorigenesis

Pharmacological research, 2022-03, Vol.177, p.106115-106115, Article 106115

2022

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Engineering stable and non-immunogenic immunoenzymes for cancer therapy via in situ generated prodrugs

Journal of controlled release, 2024-05, Vol.369, p.179-198

2024

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Structural basis of polyethylene glycol recognition by antibody

Journal of biomedical science, 2020-01, Vol.27 (1), p.12-12, Article 12

2020

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Reversible glycosidic switch for secure delivery of molecular nanocargos

Nature communications, 2018-05, Vol.9 (1), p.1843-13, Article 1843

2018

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Signal peptide-CUB-EGF-like repeat-containing protein 1-promoted FLT3 signaling is critical for the initiation and maintenance of MLL-rearranged acute leukemia

Haematologica (Roma), 2023-05, Vol.108 (5), p.1284

2023

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Disruption of Scube2 Impairs Endochondral Bone Formation

Journal of bone and mineral research, 2015-07, Vol.30 (7), p.1255-1267

2015

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Flow cytometry analysis of anti-polyethylene glycol antibodies in human plasma

Toxicology reports, 2021-01, Vol.8, p.148-154

2021

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Polyethylene Glycol Immunogenicity: Theoretical, Clinical, and Practical Aspects of Anti-Polyethylene Glycol Antibodies

CD44v6 Dependence of Premetastatic Niche Preparation by Exosomes

Interactions between nanoparticle corona proteins and the immune system

Premature Drug Release from Polyethylene Glycol (PEG)-Coated Liposomal Doxorubicin via Formation of the Membrane Attack Complex

Measurement of Pre-Existing IgG and IgM Antibodies against Polyethylene Glycol in Healthy Individuals

Conditional internalization of PEGylated nanomedicines by PEG engagers for triple negative breast cancer therapy

Liposomes with Low Levels of Grafted Poly(ethylene glycol) Remain Susceptible to Destabilization by Anti-Poly(ethylene glycol) Antibodies

Antibodies against Poly(ethylene glycol) Activate Innate Immune Cells and Induce Hypersensitivity Reactions to PEGylated Nanomedicines

Display of GPI‐anchored anti‐EGFR nanobodies on extracellular vesicles promotes tumour cell targeting

Accelerated clearance by antibodies against methoxy PEG depends on pegylation architecture

Effect of Cellular Location of Human Carboxylesterase 2 on CPT-11 Hydrolysis and Anticancer Activity

The interplay between membrane topology and mechanical forces in regulating T cell receptor activity

A genome-wide association study identifies a novel susceptibility locus for the immunogenicity of polyethylene glycol

Glucuronides: From biological waste to bio-nanomedical applications

Replacement of L-amino acid peptides with D-amino acid peptides mitigates anti-PEG antibody generation against polymer-peptide conjugates in mice

Pre-existing anti-polyethylene glycol antibody reduces the therapeutic efficacy and pharmacokinetics of PEGylated liposomes

Analytical Measurement of PEGylated Molecules

Bispecific T-cell engagers non-covalently decorated drug-loaded PEGylated nanocarriers for cancer immunochemotherapy

Inhibition of gut microbial β-glucuronidase effectively prevents carcinogen-induced microbial dysbiosis and intestinal tumorigenesis

Engineering stable and non-immunogenic immunoenzymes for cancer therapy via in situ generated prodrugs

Structural basis of polyethylene glycol recognition by antibody

Reversible glycosidic switch for secure delivery of molecular nanocargos

Signal peptide-CUB-EGF-like repeat-containing protein 1-promoted FLT3 signaling is critical for the initiation and maintenance of MLL-rearranged acute leukemia

Disruption of Scube2 Impairs Endochondral Bone Formation

Flow cytometry analysis of anti-polyethylene glycol antibodies in human plasma

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