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OGG1 Inhibition Triggers Synthetic Lethality and Enhances The Effect of PARP Inhibitor Olaparib in BRCA1-Deficient TNBC Cells

Frontiers in oncology, 2022-05, Vol.12, p.888810-888810

2022

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Restored glyoxylate metabolism after AGXT gene correction and direct reprogramming of primary hyperoxaluria type 1 fibroblasts

iScience, 2024-04, Vol.27 (4), p.109530-109530, Article 109530

2024

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Alterations in SLC4A2, SLC26A7 and SLC26A9 Drive Acid-Base Imbalance in Gastric Neuroendocrine Tumors and Uncover a Novel Mechanism for a Co-Occurring Polyautoimmune Scenario

Cells (Basel, Switzerland), 2021-12, Vol.10 (12), p.3500

2021

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DNA methylation profiles and their relationship with cytogenetic status in adult acute myeloid leukemia

PloS one, 2010-08, Vol.5 (8), p.e12197-e12197

2010

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Generation and characterization of a human iPSC cell line expressing inducible Cas9 in the “safe harbor” AAVS1 locus

Stem cell research, 2017-05, Vol.21 (C), p.137-140

2017

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MGMT genomic rearrangements contribute to chemotherapy resistance in gliomas

Nature communications, 2020-08, Vol.11 (1), p.1-10, Article 3883

2020

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NHEJ-Mediated Repair of CRISPR-Cas9-Induced DNA Breaks Efficiently Corrects Mutations in HSPCs from Patients with Fanconi Anemia

Cell stem cell, 2019-11, Vol.25 (5), p.607-621.e7

2019

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CRISPR/Cas9 for Cancer Therapy: Hopes and Challenges

Biomedicines, 2018-11, Vol.6 (4), p.105

2018

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Regulation of Myc transcription by an enhancer cluster dedicated to pluripotency and early embryonic expression

Nature communications, 2024-05, Vol.15 (1), p.3931-3931

2024

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Somatic genome editing with the RCAS-TVA-CRISPR-Cas9 system for precision tumor modeling

Nature communications, 2018-04, Vol.9 (1), p.1466-16, Article 1466

2018

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CRISPR-Cas9: A Revolutionary Tool for Cancer Modelling

International journal of molecular sciences, 2015-09, Vol.16 (9), p.22151-22168

2015

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mTORC1 Inactivation Promotes Colitis-Induced Colorectal Cancer but Protects from APC Loss-Dependent Tumorigenesis

Cell metabolism, 2018-01, Vol.27 (1), p.118-135.e8

2018

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CRISPR Approaches for the Diagnosis of Human Diseases

International journal of molecular sciences, 2022-02, Vol.23 (3), p.1757

2022

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The TINCR ubiquitin-like microprotein is a tumor suppressor in squamous cell carcinoma

Nature communications, 2023-03, Vol.14 (1), p.1328-1328, Article 1328

2023

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Therapeutic gene editing in CD34+ hematopoietic progenitors from Fanconi anemia patients

EMBO molecular medicine, 2017-11, Vol.9 (11), p.1574-1588

2017

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Efficient Recreation of t(11;22) EWSR1-FLI1+ in Human Stem Cells Using CRISPR/Cas9

Stem cell reports, 2017-05, Vol.8 (5), p.1408-1420

2017

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TALEN mediated gene editing in a mouse model of Fanconi anemia

Scientific reports, 2020-04, Vol.10 (1), p.6997-6997, Article 6997

2020

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Comprehensive characterization of a novel, oncogenic and targetable SEPTIN6::ABL2 fusion in T-ALL

British journal of haematology, 2023-08, Vol.202 (3), p.693-698

2023

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Detection of chromosome instability by interphase FISH in mouse and human tissues

STAR protocols, 2021-09, Vol.2 (3), p.100631-100631, Article 100631

2021

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Biallelic germline mutations in MAD1L1 induce a syndrome of aneuploidy with high tumor susceptibility

Science advances, 2022-11, Vol.8 (44), p.eabq5914-eabq5914

2022

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Kras oncogene ablation prevents resistance in advanced lung adenocarcinomas

The Journal of clinical investigation, 2023-04, Vol.133 (7), p.1-13

2023

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Robustness of Catalytically Dead Cas9 Activators in Human Pluripotent and Mesenchymal Stem Cells

Molecular therapy. Nucleic acids, 2020-06, Vol.20, p.196-204

2020

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OGG1 Inhibition Triggers Synthetic Lethality and Enhances The Effect of PARP Inhibitor Olaparib in BRCA1-Deficient TNBC Cells

Restored glyoxylate metabolism after AGXT gene correction and direct reprogramming of primary hyperoxaluria type 1 fibroblasts

Alterations in SLC4A2, SLC26A7 and SLC26A9 Drive Acid-Base Imbalance in Gastric Neuroendocrine Tumors and Uncover a Novel Mechanism for a Co-Occurring Polyautoimmune Scenario

DNA methylation profiles and their relationship with cytogenetic status in adult acute myeloid leukemia

Generation and characterization of a human iPSC cell line expressing inducible Cas9 in the “safe harbor” AAVS1 locus

MGMT genomic rearrangements contribute to chemotherapy resistance in gliomas

NHEJ-Mediated Repair of CRISPR-Cas9-Induced DNA Breaks Efficiently Corrects Mutations in HSPCs from Patients with Fanconi Anemia

CRISPR/Cas9 for Cancer Therapy: Hopes and Challenges

Regulation of Myc transcription by an enhancer cluster dedicated to pluripotency and early embryonic expression

Somatic genome editing with the RCAS-TVA-CRISPR-Cas9 system for precision tumor modeling

CRISPR-Cas9: A Revolutionary Tool for Cancer Modelling

Gain-of-function mutations in DNMT3A in patients with paraganglioma

mTORC1 Inactivation Promotes Colitis-Induced Colorectal Cancer but Protects from APC Loss-Dependent Tumorigenesis

CRISPR Approaches for the Diagnosis of Human Diseases

The TINCR ubiquitin-like microprotein is a tumor suppressor in squamous cell carcinoma

Therapeutic gene editing in CD34+ hematopoietic progenitors from Fanconi anemia patients

Impaired condensin complex and Aurora B kinase underlie mitotic and chromosomal defects in hyperdiploid B-cell ALL

Expression of HMGCS2 in intestinal epithelial cells is downregulated in inflammatory bowel disease associated with endoplasmic reticulum stress

Efficient Recreation of t(11;22) EWSR1-FLI1+ in Human Stem Cells Using CRISPR/Cas9

TALEN mediated gene editing in a mouse model of Fanconi anemia

Comprehensive characterization of a novel, oncogenic and targetable SEPTIN6::ABL2 fusion in T-ALL

Detection of chromosome instability by interphase FISH in mouse and human tissues

Biallelic germline mutations in MAD1L1 induce a syndrome of aneuploidy with high tumor susceptibility

Kras oncogene ablation prevents resistance in advanced lung adenocarcinomas

Robustness of Catalytically Dead Cas9 Activators in Human Pluripotent and Mesenchymal Stem Cells

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