UB Paderborn / Katalog / Suche / in CDI

Sortiert nach

Einfacher Volltextzugriff von (fast) überall

Installieren Sie die LibKey Nomad-Browsererweiterung und erhalten Sie von vielen Webseiten einfachen Zugriff auf lizenzierte Volltexte oder Open Access Publikationen. Mehr erfahren...

Recent advances in drug discovery of GPCR allosteric modulators for neurodegenerative disorders

Current opinion in pharmacology, 2017-02, Vol.32, p.91-95

2017

Volltextzugriff (PDF)

Discovery of 1‑Butyl-3-chloro-4-(4-phenyl-1-piperidinyl)-(1H)‑pyridone (JNJ-40411813): A Novel Positive Allosteric Modulator of the Metabotropic Glutamate 2 Receptor

Journal of medicinal chemistry, 2014-08, Vol.57 (15), p.6495-6512

2014

Volltextzugriff (PDF)

G-protein activation by a metabotropic glutamate receptor

Nature (London), 2021-07, Vol.595 (7867), p.450-454

2021

Volltextzugriff (PDF)

mGluR5 negative allosteric modulators overview: a medicinal chemistry approach towards a series of novel therapeutic agents

Current topics in medicinal chemistry, 2011-03, Vol.11 (6), p.680-695

2011

Volltextzugriff (PDF)

Effect of the Metabotropic Glutamate Receptor Type 5 Negative Allosteric Modulator Dipraglurant on Motor and Non-Motor Symptoms of Parkinson's Disease

Cells (Basel, Switzerland), 2023-03, Vol.12 (7), p.1004

2023

Volltextzugriff (PDF)

Boron Nitride Interphase in Ceramic-Matrix Composites

Journal of the American Ceramic Society, 1991-10, Vol.74 (10), p.2482-2488

1991

Volltextzugriff (PDF)

Discovery of 1,4-Disubstituted 3-Cyano-2-pyridones: A New Class of Positive Allosteric Modulators of the Metabotropic Glutamate 2 Receptor

Journal of medicinal chemistry, 2012-03, Vol.55 (5), p.2388-2405

2012

Volltextzugriff (PDF)

A novel series of metabotropic glutamate receptor 5 negative allosteric modulators based on a 4,5,6,7-tetrahydropyrazolo[1,5-a]pyridine core

Bioorganic & medicinal chemistry letters, 2013-08, Vol.23 (16), p.4523-4527

2013

Volltextzugriff (PDF)

New technologies enabling the industrialization of allosteric modulator discovery

Drug discovery today. Technologies, 2013, Vol.10 (2), p.e253-e260

2013

Volltextzugriff (PDF)

New positive allosteric modulators of the metabotropic glutamate receptor 2 (mGluR2): Identification and synthesis of N-propyl-8-chloro-6-substituted isoquinolones

Bioorganic & medicinal chemistry letters, 2011-02, Vol.21 (3), p.971-976

2011

Volltextzugriff (PDF)

mGluR2 Activators and mGluR5 Blockers Advancing in the Clinic for Major CNS Disorders

Annual Reports in Medicinal Chemistry, 2012, Vol.47, p.71-88

2012

Volltextzugriff (PDF)

Syntheses, activity and modeling studies of 3- and 4-(sulfo- and sulfonamidoalkyl)pyridine and piperidine-2-carboxylic acid derivatives as analogs of NMDA receptor antagonists

Bioorganic & medicinal chemistry, 1995-09, Vol.3 (9), p.1183-1201

1995

Volltextzugriff (PDF)

Electron impact mass spectra of 5-carboxymethyl dihydro-[2H]-pyran-2-ones

Organic Mass Spectrometry, 1987-12, Vol.22 (12), p.802-804

1987

Volltextzugriff (PDF)

Strategies in the Search for New Lead Compounds or Original Working Hypotheses

Practice of Medicinal Chemistry, 2015, p.2-2

4th Edition, 2015

Volltextzugriff (PDF)

Synthese et isomerisation de methoxycarbonyl-5 dihydropyrannones-2

Journal of heterocyclic chemistry, 1988-03, Vol.25 (2), p.599-601

1988

Volltextzugriff (PDF)

Chapter 12 - Application Strategies for the Primary Structure–Activity Relationship Exploration

The Practice of Medicinal Chemistry, 2015, p.301-318

Fourth Edition, 2015

Volltextzugriff (PDF)

Chapter 4 - Strategies in the Search for New Lead Compounds or Original Working Hypotheses

The Practice of Medicinal Chemistry, 2015, p.73-99

Fourth Edition, 2015

Volltextzugriff (PDF)

Application Strategies for the Primary Structure-Activity Relationship Exploration

Practice of Medicinal Chemistry, 2015, p.1-2

4th Edition, 2015

Volltextzugriff (PDF)

Synthese et isomerisation de methoxycarbonyl‐5 dihydropyrannones‐2

Journal of heterocyclic chemistry, 1988-03, Vol.25 (2), p.599-601

1988

Volltextzugriff (PDF)

Occurrence of estrogens in sewage sludge and their fate during plant-scale anaerobic digestion

Chemosphere (Oxford), 2010-09, Vol.81 (1), p.65-71

2010

Volltextzugriff (PDF)

Replacement of primary monkey kidney cells by L20B cell line in the test for effective inactivation of inactivated poliovirus vaccine

Journal of virological methods, 2018-06, Vol.256, p.77-84

2018

Volltextzugriff (PDF)

Hypersusceptibility to Azole Antifungals in a Clinical Isolate of Candida glabrata with Reduced Aerobic Growth

Antimicrobial Agents and Chemotherapy, 2009-07, Vol.53 (7), p.3034-3041

2009

Volltextzugriff (PDF)

1 – 25 von 33

Suche als RSS-Feed

Suchergebnisse filtern

Filter anzeigen

Nur zeigen

Geprüft (Peer-Review)
(26)
Mit Volltextzugriff
(22)

Publikationsform

Artikel
(28)
Buchkapitel
(5)

Sprache

Erscheinungsjahr

n.n

Thema

Science & Technology
(21)
Life Sciences & Biomedicine
(17)
Humans
(13)
Pharmacology & Pharmacy
(11)
Chemistry, Medicinal
(8)
Animals
(7)
Allosteric Regulation
(6)
Pyridines - Pharmacology
(6)
Structure-Activity Relationship
(6)
Female
(5)
Glutamate
(5)
Pyridines - Chemistry
(5)
Receptors, Metabotropic Glutamate - Metabolism
(5)
Analoging
(4)
Biochemistry & Molecular Biology
(4)
Biological And Medical Sciences
(4)
Chemistry
(4)
Chemistry, Organic
(4)
Male
(4)
Medical Sciences
(4)

15 weitere anzeigen...

Weniger anzeigen...

Menü

Weitere Dienste

Einstellungen

Recent advances in drug discovery of GPCR allosteric modulators for neurodegenerative disorders

Discovery of 1‑Butyl-3-chloro-4-(4-phenyl-1-piperidinyl)-(1H)‑pyridone (JNJ-40411813): A Novel Positive Allosteric Modulator of the Metabotropic Glutamate 2 Receptor

G-protein activation by a metabotropic glutamate receptor

mGluR5 negative allosteric modulators overview: a medicinal chemistry approach towards a series of novel therapeutic agents

Effect of the Metabotropic Glutamate Receptor Type 5 Negative Allosteric Modulator Dipraglurant on Motor and Non-Motor Symptoms of Parkinson's Disease

Mechanism based neurotoxicity of mGlu5 positive allosteric modulators – Development challenges for a promising novel antipsychotic target

Boron Nitride Interphase in Ceramic-Matrix Composites

Discovery of 1,4-Disubstituted 3-Cyano-2-pyridones: A New Class of Positive Allosteric Modulators of the Metabotropic Glutamate 2 Receptor

A novel series of metabotropic glutamate receptor 5 negative allosteric modulators based on a 4,5,6,7-tetrahydropyrazolo[1,5-a]pyridine core

New technologies enabling the industrialization of allosteric modulator discovery

New positive allosteric modulators of the metabotropic glutamate receptor 2 (mGluR2): Identification and synthesis of N-propyl-8-chloro-6-substituted isoquinolones

Discovery of 1,5-Disubstituted Pyridones: A New Class of Positive Allosteric Modulators of the Metabotropic Glutamate 2 Receptor

New positive allosteric modulators of the metabotropic glutamate receptor 2 (mGluR2). Identification and synthesis of N-propyl-5-substituted isoquinolones

mGluR2 Activators and mGluR5 Blockers Advancing in the Clinic for Major CNS Disorders

Syntheses, activity and modeling studies of 3- and 4-(sulfo- and sulfonamidoalkyl)pyridine and piperidine-2-carboxylic acid derivatives as analogs of NMDA receptor antagonists

Electron impact mass spectra of 5-carboxymethyl dihydro-[2H]-pyran-2-ones

Strategies in the Search for New Lead Compounds or Original Working Hypotheses

Synthese et isomerisation de methoxycarbonyl-5 dihydropyrannones-2

Chapter 12 - Application Strategies for the Primary Structure–Activity Relationship Exploration

Chapter 4 - Strategies in the Search for New Lead Compounds or Original Working Hypotheses

Application Strategies for the Primary Structure-Activity Relationship Exploration

Synthese et isomerisation de methoxycarbonyl‐5 dihydropyrannones‐2

Occurrence of estrogens in sewage sludge and their fate during plant-scale anaerobic digestion

Replacement of primary monkey kidney cells by L20B cell line in the test for effective inactivation of inactivated poliovirus vaccine

Hypersusceptibility to Azole Antifungals in a Clinical Isolate of Candida glabrata with Reduced Aerobic Growth

Suchergebnisse filtern