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11β-hydroxysteroid dehydrogenase type 1 gene knockout attenuates atherosclerosis and in vivo foam cell formation in hyperlipidemic apoE⁻/⁻ mice

PloS one, 2013-02, Vol.8 (2), p.e53192-e53192

2013

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2-Hydroxy- N-arylbenzenesulfonamides as ATP-citrate lyase inhibitors

Bioorganic & medicinal chemistry letters, 2007-06, Vol.17 (11), p.3208-3211

2007

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(3R,5S,E)-7-(4-(4-Fluorophenyl)-6-isopropyl-2-(methyl(1-methyl-1H-1,2,4-triazol-5-yl)amino)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoic Acid (BMS-644950): A Rationally Designed Orally Efficacious 3-Hydroxy-3-methylglutaryl Coenzyme-A Reductase Inhibitor with Reduced Myotoxicity Potential

Journal of medicinal chemistry, 2008-05, Vol.51 (9), p.2722-2733

2008

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5-Carboxamido-1,3,2-dioxaphosphorinanes, Potent Inhibitors of MTP

ChemInform, 2005-01, Vol.36 (4), p.no-no

2005

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5-Carboxamido-1,3,2-dioxaphosphorinanes, potent inhibitors of MTP

Bioorganic & medicinal chemistry letters, 2004-10, Vol.14 (20), p.5067-5070

2004

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Accounts in drug discovery: case studies in medicinal chemistry.

1, 2010

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Acridone-Based Inhibitors of Inosine 5‘-Monophosphate Dehydrogenase: Discovery and SAR Leading to the Identification of N-(2-(6-(4-Ethylpiperazin-1-yl)pyridin-3-yl)propan-2-yl)-2- fluoro-9-oxo-9,10-dihydroacridine-3-carboxamide (BMS-566419)

Journal of medicinal chemistry, 2007-07, Vol.50 (15), p.3730-3742

2007

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Amino(methyl) pyrrolidines as novel scaffolds for factor Xa inhibitors

Bioorganic & medicinal chemistry letters, 2007-11, Vol.17 (21), p.5952-5958

2007

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Arylsulfonamidopiperidone derivatives as a novel class of factor Xa inhibitors

Bioorganic & medicinal chemistry letters, 2011-12, Vol.21 (24), p.7516-7521

2011

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ATTEMPTS TO ESTABLISH EXPERIMENTAL CYCLOSPORA CAYETANENSIS INFECTION IN LABORATORY ANIMALS

The Journal of parasitology, 2000-06, Vol.86 (3), p.577-582

2000

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Attempts to Establish Experimental Cyclospora cayetanensis Infection in Laboratory Animals

The Journal of parasitology, 2000, Vol.86 (3), p.577

2000

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Chapter 1 - The Discovery of the Dipeptidyl Peptidase-4 (DPP4) Inhibitor Onglyza™: From Concept to Market

Accounts in Drug Discovery: Case Studies in Medicinal Chemistry, 2011, p.1-24

2011

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ChemInform Abstract: A General Synthesis of Dioxolenone Prodrug Moieties

ChemInform, 2002-05, Vol.33 (21), p.no-no

2002

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ChemInform Abstract: N-Formyl Hydroxylamine Containing Dipeptides: Generation of a New Class of Vasopeptidase Inhibitors

ChemInform, 2000-05, Vol.31 (21), p.no-no

2000

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ChemPlate and Hopkins, a template and font for drawing molecular structures with the Macintosh computer

Journal of chemical education, 1987-02, Vol.64 (2), p.135

1987

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A Convenient Synthesis of Tetrazolo[1,5-a]-α-cycloalkanones

ChemInform, 2007-04, Vol.38 (17), p.no-no

2007

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A convenient synthesis of tetrazolo[1,5- a]-α-cycloalkanones

Tetrahedron letters, 2007-01, Vol.48 (4), p.555-558

2007

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( d)-2- tert-Butoxycarbonylamino-5,5-difluoro-5-phenyl-pentanoic acid: Synthesis and incorporation into the growth hormone secretagogues

Bioorganic & medicinal chemistry, 2008-07, Vol.18 (14), p.4072-4074

2008

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Design and synthesis of tetrazole-based growth hormone secretagogue: The SAR studies of the O-benzyl serine side chain

Bioorganic & medicinal chemistry, 2008-03, Vol.18 (6), p.1825-1829

2008

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Design, synthesis, and SAR studies of novel polycyclic acids as potent and selective inhibitors of human 11I super(2)-hydroxysteroid dehydrogenase type 1 (11I super(2)-HSD-1)

Bioorganic & medicinal chemistry letters, 2011-11, Vol.21 (22), p.6699-6704

2011

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Design, synthesis, and SAR studies of novel polycyclic acids as potent and selective inhibitors of human 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD-1)

Bioorganic & medicinal chemistry letters, 2011-11, Vol.21 (22), p.6699-6704

2011

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Dihydropyrrolopyrazol-6-one MCHR1 antagonists for the treatment of obesity: Insights on in vivo efficacy from a novel FLIPR assay setup

Bioorganic & medicinal chemistry letters, 2015-07, Vol.25 (14), p.2793-2799

2015

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Diprolyl nitriles as potent dipeptidyl peptidase IV inhibitors

Bioorganic & medicinal chemistry letters, 2005-09, Vol.15 (18), p.3992-3995

2005

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11[beta]-Hydroxysteroid Dehydrogenase Type 1 Gene Knockout Attenuates Atherosclerosis and In Vivo Foam Cell Formation in Hyperlipidemic apoE.sup.-/- Mice

11β-hydroxysteroid dehydrogenase type 1 gene knockout attenuates atherosclerosis and in vivo foam cell formation in hyperlipidemic apoE⁻/⁻ mice

2-Hydroxy- N-arylbenzenesulfonamides as ATP-citrate lyase inhibitors

(3R,5S,E)-7-(4-(4-Fluorophenyl)-6-isopropyl-2-(methyl(1-methyl-1H-1,2,4-triazol-5-yl)amino)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoic Acid (BMS-644950): A Rationally Designed Orally Efficacious 3-Hydroxy-3-methylglutaryl Coenzyme-A Reductase Inhibitor with Reduced Myotoxicity Potential

5-Carboxamido-1,3,2-dioxaphosphorinanes, Potent Inhibitors of MTP

5-Carboxamido-1,3,2-dioxaphosphorinanes, potent inhibitors of MTP

Accounts in drug discovery: case studies in medicinal chemistry.

Acridone-Based Inhibitors of Inosine 5‘-Monophosphate Dehydrogenase: Discovery and SAR Leading to the Identification of N-(2-(6-(4-Ethylpiperazin-1-yl)pyridin-3-yl)propan-2-yl)-2- fluoro-9-oxo-9,10-dihydroacridine-3-carboxamide (BMS-566419)

Acridone-based inhibitors of inosine 5'-monophosphate dehydrogenase : Discovery and sar leading to the identification of N-2 -(6 -(4 -ethylpiperazin -L-yl )pyridin -3 -yl )propan -2 -yl -2-fluoro-9-oxo-9,10-dihydroacridine-3-carboxamide (BMS-566419)

Amino(methyl) pyrrolidines as novel scaffolds for factor Xa inhibitors

Arylsulfonamidopiperidone derivatives as a novel class of factor Xa inhibitors

ATTEMPTS TO ESTABLISH EXPERIMENTAL CYCLOSPORA CAYETANENSIS INFECTION IN LABORATORY ANIMALS

Attempts to Establish Experimental Cyclospora cayetanensis Infection in Laboratory Animals

Chapter 1 - The Discovery of the Dipeptidyl Peptidase-4 (DPP4) Inhibitor Onglyza™: From Concept to Market

ChemInform Abstract: A General Synthesis of Dioxolenone Prodrug Moieties

ChemInform Abstract: N-Formyl Hydroxylamine Containing Dipeptides: Generation of a New Class of Vasopeptidase Inhibitors

ChemPlate and Hopkins, a template and font for drawing molecular structures with the Macintosh computer

A Convenient Synthesis of Tetrazolo[1,5-a]-α-cycloalkanones

A convenient synthesis of tetrazolo[1,5- a]-α-cycloalkanones

( d)-2- tert-Butoxycarbonylamino-5,5-difluoro-5-phenyl-pentanoic acid: Synthesis and incorporation into the growth hormone secretagogues

Design and synthesis of tetrazole-based growth hormone secretagogue: The SAR studies of the O-benzyl serine side chain

Design, synthesis, and SAR studies of novel polycyclic acids as potent and selective inhibitors of human 11I super(2)-hydroxysteroid dehydrogenase type 1 (11I super(2)-HSD-1)

Design, synthesis, and SAR studies of novel polycyclic acids as potent and selective inhibitors of human 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD-1)

Dihydropyrrolopyrazol-6-one MCHR1 antagonists for the treatment of obesity: Insights on in vivo efficacy from a novel FLIPR assay setup

Diprolyl nitriles as potent dipeptidyl peptidase IV inhibitors

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