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FUS functions in coupling transcription to splicing by mediating an interaction between RNAP II and U1 snRNP

Proceedings of the National Academy of Sciences - PNAS, 2015-07, Vol.112 (28), p.8608-8613

2015

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An extensive network of coupling among gene expression machines

Nature (London), 2002-04, Vol.416 (6880), p.499-506

2002

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The anti-tumor drug E7107 reveals an essential role for SF3b in remodeling U2 snRNP to expose the branch point-binding region

Genes & development, 2011-03, Vol.25 (5), p.440-444

2011

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Splicing promotes rapid and efficient mRNA export in mammalian cells

Proceedings of the National Academy of Sciences - PNAS, 2008-03, Vol.105 (9), p.3386-3391

2008

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A role for TREX components in the release of spliced mRNA from nuclear speckle domains

Nature communications, 2010-10, Vol.1 (7), p.97-97, Article 97

2010

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Export and stability of naturally intronless mRNAs require specific coding region sequences and the TREX mRNA export complex

Proceedings of the National Academy of Sciences - PNAS, 2011-11, Vol.108 (44), p.17985-17990

2011

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Human mRNA Export Machinery Recruited to the 5′ End of mRNA

Cell, 2006-12, Vol.127 (7), p.1389-1400

2006

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Mechanisms of fidelity in pre-mRNA splicing

Current Opinion in Cell Biology, 2000-06, Vol.12 (3), p.340-345

Reed, Robin

2000

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ATP is required for interactions between UAP56 and two conserved mRNA export proteins, Aly and CIP29, to assemble the TREX complex

Genes & development, 2010-09, Vol.24 (18), p.2043-2053

2010

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Evidence that C9ORF72 Dipeptide Repeat Proteins Associate with U2 snRNP to Cause Mis-splicing in ALS/FTD Patients

Cell reports (Cambridge), 2017-06, Vol.19 (11), p.2244-2256

2017

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The neurodegenerative diseases ALS and SMA are linked at the molecular level via the ASC-1 complex

Nucleic acids research, 2018-12, Vol.46 (22), p.11939-11951

2018

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Recruitment of the human TREX complex to mRNA during splicing

Genes & development, 2005-07, Vol.19 (13), p.1512-1517

2005

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U1 snRNP is mislocalized in ALS patient fibroblasts bearing NLS mutations in FUS and is required for motor neuron outgrowth in zebrafish

Nucleic acids research, 2015-03, Vol.43 (6), p.3208-3218

2015

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TREX exposes the RNA-binding domain of Nxf1 to enable mRNA export

Nature communications, 2012, Vol.3 (1), p.1006-1006, Article 1006

2012

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Development of NAMASTE (New Anxiety Management Algorithm Standardizing Treatment Experience) and Implementation in Primary Care

Psychiatric services (Washington, D.C.), 2020-06, Vol.71 (6), p.627-630

2020

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SR Proteins Function in Coupling RNAP II Transcription to Pre-mRNA Splicing

Molecular cell, 2007-06, Vol.26 (6), p.867-881

2007

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FUS-SMN Protein Interactions Link the Motor Neuron Diseases ALS and SMA

Cell reports (Cambridge), 2012-10, Vol.2 (4), p.799-806

2012

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A U2-snRNP–independent role of SF3b in promoting mRNA export

Proceedings of the National Academy of Sciences - PNAS, 2019-04, Vol.116 (16), p.7837-7846

2019

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Comprehensive proteomic analysis of the human spliceosome

Nature (London), 2002-09, Vol.419 (6903), p.182-185

2002

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The proteins PDIP3 and ZC11A associate with the human TREX complex in an ATP-dependent manner and function in mRNA export

PloS one, 2012-08, Vol.7 (8), p.e43804-e43804

2012

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Initial splice-site recognition and pairing during pre-mRNA splicing

Current opinion in genetics & development, 1996-04, Vol.6 (2), p.215-220

Reed, Robin

1996

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Sus1, a Functional Component of the SAGA Histone Acetylase Complex and the Nuclear Pore-Associated mRNA Export Machinery

Cell, 2004-01, Vol.116 (1), p.75-86

2004

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Splicing Is Required for Rapid and Efficient mRNA Export in Metazoans

Proceedings of the National Academy of Sciences - PNAS, 1999-12, Vol.96 (26), p.14937-14942

1999

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Functional coupling of RNAP II transcription to spliceosome assembly

Genes & development, 2006-05, Vol.20 (9), p.1100-1109

2006

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FUS functions in coupling transcription to splicing by mediating an interaction between RNAP II and U1 snRNP

An extensive network of coupling among gene expression machines

The anti-tumor drug E7107 reveals an essential role for SF3b in remodeling U2 snRNP to expose the branch point-binding region

Splicing promotes rapid and efficient mRNA export in mammalian cells

A role for TREX components in the release of spliced mRNA from nuclear speckle domains

Export and stability of naturally intronless mRNAs require specific coding region sequences and the TREX mRNA export complex

Transcriptomic Characterization of SF3B1 Mutation Reveals Its Pleiotropic Effects in Chronic Lymphocytic Leukemia

Human mRNA Export Machinery Recruited to the 5′ End of mRNA

Mechanisms of fidelity in pre-mRNA splicing

ATP is required for interactions between UAP56 and two conserved mRNA export proteins, Aly and CIP29, to assemble the TREX complex

Evidence that C9ORF72 Dipeptide Repeat Proteins Associate with U2 snRNP to Cause Mis-splicing in ALS/FTD Patients

The neurodegenerative diseases ALS and SMA are linked at the molecular level via the ASC-1 complex

Recruitment of the human TREX complex to mRNA during splicing

U1 snRNP is mislocalized in ALS patient fibroblasts bearing NLS mutations in FUS and is required for motor neuron outgrowth in zebrafish

TREX exposes the RNA-binding domain of Nxf1 to enable mRNA export

Development of NAMASTE (New Anxiety Management Algorithm Standardizing Treatment Experience) and Implementation in Primary Care

SR Proteins Function in Coupling RNAP II Transcription to Pre-mRNA Splicing

FUS-SMN Protein Interactions Link the Motor Neuron Diseases ALS and SMA

A U2-snRNP–independent role of SF3b in promoting mRNA export

Comprehensive proteomic analysis of the human spliceosome

The proteins PDIP3 and ZC11A associate with the human TREX complex in an ATP-dependent manner and function in mRNA export

Initial splice-site recognition and pairing during pre-mRNA splicing

Sus1, a Functional Component of the SAGA Histone Acetylase Complex and the Nuclear Pore-Associated mRNA Export Machinery

Splicing Is Required for Rapid and Efficient mRNA Export in Metazoans

Functional coupling of RNAP II transcription to spliceosome assembly

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