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Revisiting the role of ABC transporters in multidrug-resistant cancer

Nature reviews. Cancer, 2018-07, Vol.18 (7), p.452-464

2018

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Mitochondrial ATP fuels ABC transporter-mediated drug efflux in cancer chemoresistance

Nature communications, 2021-05, Vol.12 (1), p.2804-19, Article 2804

2021

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Sunitinib (Sutent, SU11248), a small-molecule receptor tyrosine kinase inhibitor, blocks function of the ATP-binding cassette (ABC) transporters P-glycoprotein (ABCB1) and ABCG2

Drug metabolism and disposition, 2009-02, Vol.37 (2), p.359-365

2009

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ABC transporters: unvalidated therapeutic targets in cancer and the CNS

Anti-cancer agents in medicinal chemistry, 2010-10, Vol.10 (8), p.625-633

2010

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The challenge of exploiting ABCG2 in the clinic

Current pharmaceutical biotechnology, 2011-04, Vol.12 (4), p.595-608

2011

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Lapatinib (Tykerb, GW572016) Reverses Multidrug Resistance in Cancer Cells by Inhibiting the Activity of ATP-Binding Cassette Subfamily B Member 1 and G Member 2

Cancer research (Chicago, Ill.), 2008-10, Vol.68 (19), p.7905-7914

2008

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Sildenafil Reverses ABCB1- and ABCG2-Mediated Chemotherapeutic Drug Resistance

Cancer research (Chicago, Ill.), 2011-04, Vol.71 (8), p.3029-3041

2011

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Leptin Signaling Affects Survival and Chemoresistance of Estrogen Receptor Negative Breast Cancer

International journal of molecular sciences, 2020-05, Vol.21 (11), p.3794

2020

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Characterization and tissue localization of zebrafish homologs of the human ABCB1 multidrug transporter

Scientific reports, 2021-12, Vol.11 (1), p.24150-24150, Article 24150

2021

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Erlotinib (Tarceva, OSI-774) Antagonizes ATP-Binding Cassette Subfamily B Member 1 and ATP-Binding Cassette Subfamily G Member 2-Mediated Drug Resistance

Cancer research (Chicago, Ill.), 2007-11, Vol.67 (22), p.11012-11020

2007

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Pheophorbide a is a specific probe for ABCG2 function and inhibition

Cancer research (Chicago, Ill.), 2004-02, Vol.64 (4), p.1242-1246

2004

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Novel Therapeutic Strategies Exploiting the Unique Properties of Neuroendocrine Neoplasms

Cancers, 2023-10, Vol.15 (20), p.4960

2023

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A Histone Deacetylase Inhibitor Induces Acetyl-CoA Depletion Leading to Lethal Metabolic Stress in RAS-Pathway Activated Cells

Cancers, 2022-05, Vol.14 (11), p.2643

2022

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Multidrug transporters: recent insights from cryo-electron microscopy-derived atomic structures and animal models [version 1; peer review: awaiting peer review]

F1000 research, 2020, Vol.9, p.17

2020

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Escape from hsa-miR-519c enables drug-resistant cells to maintain high expression of ABCG2

Molecular cancer therapeutics, 2009-10, Vol.8 (10), p.2959-2968

2009

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Abcg2a is the functional homolog of human ABCG2 expressed at the zebrafish blood-brain barrier

Fluids and barriers of the CNS, 2024-03, Vol.21 (1), p.27-27, Article 27

2024

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Cross-resistance of cisplatin selected cells to anti-microtubule agents: Role of general survival mechanisms

Translational oncology, 2021-01, Vol.14 (1), p.100917-100917, Article 100917

2021

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CCR 20th Anniversary Commentary: Expanding the Epigenetic Therapeutic Portfolio

Clinical cancer research, 2015-05, Vol.21 (10), p.2195-2197

2015

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Association of variant ABCG2 and the pharmacokinetics of epidermal growth factor receptor tyrosine kinase inhibitors in cancer patients

Cancer biology & therapy, 2007-03, Vol.6 (3), p.432-438

2007

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Side Population Analysis Using a Violet‐Excited Cell‐Permeable DNA Binding Dye

Stem cells (Dayton, Ohio), 2007-04, Vol.25 (4), p.1029-1036

2007

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ABCG2-mediated transport of photosensitizers: Potential impact on photodynamic therapy

Cancer biology & therapy, 2005-02, Vol.4 (2), p.195-202

2005

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Ibrutinib disrupts blood-tumor barrier integrity and prolongs survival in rodent glioma model

Acta neuropathologica communications, 2024-04, Vol.12 (1), p.56-56, Article 56

2024

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Phase I Trial of the Histone Deacetylase Inhibitor, Depsipeptide (FR901228, NSC 630176), in Patients with Refractory Neoplasms

Clinical cancer research, 2002-03, Vol.8 (3), p.718

2002

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Histone deacetylase inhibitor-mediated cell death is distinct from its global effect on chromatin

Molecular oncology, 2014-12, Vol.8 (8), p.1379-1392

2014

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Proteasome inhibitors increase tubulin polymerization and stabilization in tissue culture cells: A possible mechanism contributing to peripheral neuropathy and cellular toxicity following proteasome inhibition

Cell cycle (Georgetown, Tex.), 2008-04, Vol.7 (7), p.940-949

2008

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Revisiting the role of ABC transporters in multidrug-resistant cancer

Mitochondrial ATP fuels ABC transporter-mediated drug efflux in cancer chemoresistance

Sunitinib (Sutent, SU11248), a small-molecule receptor tyrosine kinase inhibitor, blocks function of the ATP-binding cassette (ABC) transporters P-glycoprotein (ABCB1) and ABCG2

ABC transporters: unvalidated therapeutic targets in cancer and the CNS

The challenge of exploiting ABCG2 in the clinic

Lapatinib (Tykerb, GW572016) Reverses Multidrug Resistance in Cancer Cells by Inhibiting the Activity of ATP-Binding Cassette Subfamily B Member 1 and G Member 2

Sildenafil Reverses ABCB1- and ABCG2-Mediated Chemotherapeutic Drug Resistance

Leptin Signaling Affects Survival and Chemoresistance of Estrogen Receptor Negative Breast Cancer

Characterization and tissue localization of zebrafish homologs of the human ABCB1 multidrug transporter

Erlotinib (Tarceva, OSI-774) Antagonizes ATP-Binding Cassette Subfamily B Member 1 and ATP-Binding Cassette Subfamily G Member 2-Mediated Drug Resistance

Pheophorbide a is a specific probe for ABCG2 function and inhibition

Novel Therapeutic Strategies Exploiting the Unique Properties of Neuroendocrine Neoplasms

A Histone Deacetylase Inhibitor Induces Acetyl-CoA Depletion Leading to Lethal Metabolic Stress in RAS-Pathway Activated Cells

Multidrug transporters: recent insights from cryo-electron microscopy-derived atomic structures and animal models [version 1; peer review: awaiting peer review]

Escape from hsa-miR-519c enables drug-resistant cells to maintain high expression of ABCG2

Abcg2a is the functional homolog of human ABCG2 expressed at the zebrafish blood-brain barrier

Cross-resistance of cisplatin selected cells to anti-microtubule agents: Role of general survival mechanisms

CCR 20th Anniversary Commentary: Expanding the Epigenetic Therapeutic Portfolio

Association of variant ABCG2 and the pharmacokinetics of epidermal growth factor receptor tyrosine kinase inhibitors in cancer patients

Side Population Analysis Using a Violet‐Excited Cell‐Permeable DNA Binding Dye

ABCG2-mediated transport of photosensitizers: Potential impact on photodynamic therapy

Ibrutinib disrupts blood-tumor barrier integrity and prolongs survival in rodent glioma model

Phase I Trial of the Histone Deacetylase Inhibitor, Depsipeptide (FR901228, NSC 630176), in Patients with Refractory Neoplasms

Histone deacetylase inhibitor-mediated cell death is distinct from its global effect on chromatin

Proteasome inhibitors increase tubulin polymerization and stabilization in tissue culture cells: A possible mechanism contributing to peripheral neuropathy and cellular toxicity following proteasome inhibition

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