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A non-catalytic scaffolding activity of hexokinase 2 contributes to EMT and metastasis

Nature communications, 2022-02, Vol.13 (1), p.899-20, Article 899

2022

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Hexokinase 2 Is Required for Tumor Initiation and Maintenance and Its Systemic Deletion Is Therapeutic in Mouse Models of Cancer

Cancer cell, 2013-08, Vol.24 (2), p.213-228

2013

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CD36-Mediated Metabolic Rewiring of Breast Cancer Cells Promotes Resistance to HER2-Targeted Therapies

Cell reports (Cambridge), 2019-12, Vol.29 (11), p.3405-3420.e5

2019

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Metabolic reprogramming and dysregulated metabolism: cause, consequence and/or enabler of environmental carcinogenesis?

Carcinogenesis (New York), 2015-06, Vol.36 Suppl 1 (Suppl 1), p.S203-S231

2015

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Akt Inhibits Apoptosis Downstream of BID Cleavage via a Glucose-Dependent Mechanism Involving Mitochondrial Hexokinases

Molecular and Cellular Biology, 2004-01, Vol.24 (2), p.730-740

2004

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Is Akt the “Warburg kinase”?—Akt-energy metabolism interactions and oncogenesis

Seminars in cancer biology, 2009-02, Vol.19 (1), p.25-31

2009

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Mitochondrial Hexokinases: Guardians of the Mitochondria

Cell cycle (Georgetown, Tex.), 2005-05, Vol.4 (5), p.654-658

2005

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Chronic Kidney Disease Progression and Cardiovascular Outcomes Following Cardiac Catheterization—A Population‐Controlled Study

Journal of the American Heart Association, 2016-10, Vol.5 (10), p.n/a

2016

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AUF1/hnRNP D represses expression of VEGF in macrophages

Molecular biology of the cell, 2012-04, Vol.23 (8), p.1414-1422

2012

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Peptides modeled on the RGG domain of AUF1/hnRNP-D regulate 3′ UTR-dependent gene expression

International immunopharmacology, 2013-09, Vol.17 (1), p.132-141

2013

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Cyclical dehydration-induced renal injury and Mesoamerican nephropathy: as sweet by any other name?

Kidney international, 2014-08, Vol.86 (2), p.226-229

Robey, R Brooks

2014

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Increased Hexokinase Activity, of Either Ectopic or Endogenous Origin, Protects Renal Epithelial Cells against Acute Oxidant-induced Cell Death

The Journal of biological chemistry, 2002-03, Vol.277 (13), p.11392-11400

2002

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Adverse Effects of Low-Dose Methotrexate

Annals of internal medicine, 2020-07, Vol.173 (2), p.166-167

2020

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Changing the terminology of cancer

JAMA : the journal of the American Medical Association, 2014-01, Vol.311 (2), p.202

Robey, R Brooks

2014

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Perspectives from the Kidney Health Initiative on Advancing Technologies to Facilitate Remote Monitoring of Patient Self-Care in RRT

Clinical journal of the American Society of Nephrology, 2017-11, Vol.12 (11), p.1900-1909

2017

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Hexokinase-Mitochondria Interaction Mediated by Akt Is Required to Inhibit Apoptosis in the Presence or Absence of Bax and Bak

Molecular cell, 2004-12, Vol.16 (5), p.819-830

2004

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Inhibition of early apoptotic events by Akt/PKB is dependent on the first committed step of glycolysis and mitochondrial hexokinase

Genes & development, 2001-06, Vol.15 (11), p.1406-1418

2001

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Potassium levels after acute myocardial infarction

JAMA : the journal of the American Medical Association, 2012-04, Vol.307 (15), p.1578

Robey, R Brooks

2012

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Hexokinase: a novel sugar kinase coupled to renal epithelial cell survival

Kidney international, 2011-06, Vol.79 (11), p.1163-1165

Robey, R. Brooks

2011

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"Does sunscreen promote hypertension?" and other questions. Novel interactions between vitamin D and the renin-angiotensin axis. Focus on "The world pandemic of vitamin D deficiency could possibly be explained by cellular inflammatory response activity induced by the renin-angiotensin system"

American Journal of Physiology: Cell Physiology, 2013-06, Vol.304 (11), p.C1040-C1041

2013

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Varenicline for smoking reduction prior to cessation

JAMA : the journal of the American Medical Association, 2015-06, Vol.313 (22), p.2285

2015

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Reduced susceptibility to azoxymethane-induced aberrant crypt foci formation and colon cancer in growth hormone deficient rats

Growth hormone & IGF research, 2009-10, Vol.19 (5), p.447-456

2009

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mTORC1 Hyperactivity Inhibits Serum Deprivation-Induced Apoptosis via Increased Hexokinase II and GLUT1 Expression, Sustained Mcl-1 Expression, and Glycogen Synthase Kinase 3β Inhibition

Molecular and Cellular Biology, 2009-09, Vol.29 (18), p.5136-5147

2009

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Effects of antiplatelet therapy on mortality and cardiovascular and bleeding outcomes in persons with chronic kidney disease

Annals of internal medicine, 2012-08, Vol.157 (4), p.302

2012

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A central role for Pyk2-Src interaction in coupling diverse stimuli to increased epithelial NBC activity

American journal of physiology. Renal physiology, 2002-10, Vol.283 (4), p.F663-F670

2002

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A non-catalytic scaffolding activity of hexokinase 2 contributes to EMT and metastasis

Hexokinase 2 Is Required for Tumor Initiation and Maintenance and Its Systemic Deletion Is Therapeutic in Mouse Models of Cancer

CD36-Mediated Metabolic Rewiring of Breast Cancer Cells Promotes Resistance to HER2-Targeted Therapies

Metabolic reprogramming and dysregulated metabolism: cause, consequence and/or enabler of environmental carcinogenesis?

Akt Inhibits Apoptosis Downstream of BID Cleavage via a Glucose-Dependent Mechanism Involving Mitochondrial Hexokinases

Is Akt the “Warburg kinase”?—Akt-energy metabolism interactions and oncogenesis

Mitochondrial Hexokinases: Guardians of the Mitochondria

Chronic Kidney Disease Progression and Cardiovascular Outcomes Following Cardiac Catheterization—A Population‐Controlled Study

AUF1/hnRNP D represses expression of VEGF in macrophages

Peptides modeled on the RGG domain of AUF1/hnRNP-D regulate 3′ UTR-dependent gene expression

Cyclical dehydration-induced renal injury and Mesoamerican nephropathy: as sweet by any other name?

Increased Hexokinase Activity, of Either Ectopic or Endogenous Origin, Protects Renal Epithelial Cells against Acute Oxidant-induced Cell Death

Adverse Effects of Low-Dose Methotrexate

Changing the terminology of cancer

Perspectives from the Kidney Health Initiative on Advancing Technologies to Facilitate Remote Monitoring of Patient Self-Care in RRT

Hexokinase-Mitochondria Interaction Mediated by Akt Is Required to Inhibit Apoptosis in the Presence or Absence of Bax and Bak

Inhibition of early apoptotic events by Akt/PKB is dependent on the first committed step of glycolysis and mitochondrial hexokinase

Potassium levels after acute myocardial infarction

Hexokinase: a novel sugar kinase coupled to renal epithelial cell survival

"Does sunscreen promote hypertension?" and other questions. Novel interactions between vitamin D and the renin-angiotensin axis. Focus on "The world pandemic of vitamin D deficiency could possibly be explained by cellular inflammatory response activity induced by the renin-angiotensin system"

Varenicline for smoking reduction prior to cessation

Reduced susceptibility to azoxymethane-induced aberrant crypt foci formation and colon cancer in growth hormone deficient rats

mTORC1 Hyperactivity Inhibits Serum Deprivation-Induced Apoptosis via Increased Hexokinase II and GLUT1 Expression, Sustained Mcl-1 Expression, and Glycogen Synthase Kinase 3β Inhibition

Effects of antiplatelet therapy on mortality and cardiovascular and bleeding outcomes in persons with chronic kidney disease

A central role for Pyk2-Src interaction in coupling diverse stimuli to increased epithelial NBC activity

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