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OSU-03012 and Viagra Treatment Inhibits the Activity of Multiple Chaperone Proteins and Disrupts the Blood-Brain Barrier: Implications for Anti-Cancer Therapies

Journal of cellular physiology, 2015-08, Vol.230 (8), p.1982-1998

2015

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GZ17-6.02 kills prostate cancer cells in vitro and in vivo

Frontiers in oncology, 2022-11, Vol.12, p.1045459-1045459

2022

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Axitinib and HDAC Inhibitors Interact to Kill Sarcoma Cells

Frontiers in oncology, 2021-09, Vol.11, p.723966-723966

2021

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The Lethality of [Pazopanib + HDAC Inhibitors] Is Enhanced by Neratinib

Frontiers in oncology, 2019-07, Vol.9, p.650-650

2019

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Fingolimod Augments Monomethylfumarate Killing of GBM Cells

Frontiers in oncology, 2020-01, Vol.10, p.22-22

2020

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The afatinib resistance of in vivo generated H1975 lung cancer cell clones is mediated by SRC/ERBB3/c-KIT/c-MET compensatory survival signaling

Oncotarget, 2016-04, Vol.7 (15), p.19620-19630

2016

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The role of cell signaling in the crosstalk between autophagy and apoptosis in the regulation of tumor cell survival in response to sorafenib and neratinib

Seminars in cancer biology, 2020-11, Vol.66, p.129-139

2020

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HDAC inhibitors enhance the immunotherapy response of melanoma cells

Oncotarget, 2017-10, Vol.8 (47), p.83155-83170

2017

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Formulated Curcumin Prevents Paclitaxel-Induced Peripheral Neuropathy through Reduction in Neuroinflammation by Modulation of α7 Nicotinic Acetylcholine Receptors

Pharmaceutics, 2022-06, Vol.14 (6), p.1296

2022

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A Fenofibrate Diet Prevents Paclitaxel-Induced Peripheral Neuropathy in Mice

Cancers, 2020-12, Vol.13 (1), p.69

2020

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Corrigendum: Fingolimod Augments Monomethylfumarate Killing of GBM Cells

Frontiers in oncology, 2020-04, Vol.10, p.684-684

2020

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AR12 (OSU-03012) suppresses GRP78 expression and inhibits SARS-CoV-2 replication

Biochemical pharmacology, 2020-12, Vol.182, p.114227-114227, Article 114227

2020

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Differential regulation of autophagy and cell viability by ceramide species

Cancer biology & therapy, 2015-01, Vol.16 (5), p.733-742

2015

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The multi-kinase inhibitor lenvatinib interacts with the HDAC inhibitor entinostat to kill liver cancer cells

Cellular signalling, 2020-06, Vol.70, p.109573, Article 109573

2020

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Autophagy as a therapeutic mechanism to kill drug-resistant cancer cells

Anti-cancer drugs, 2024-02, Vol.35 (2), p.177-182

2024

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(Curcumin+sildenafil) enhances the efficacy of 5FU and anti‐PD1 therapies in vivo

Journal of cellular physiology, 2020-10, Vol.235 (10), p.6862-6874

2020

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Neratinib inhibits Hippo/YAP signaling, reduces mutant K-RAS expression, and kills pancreatic and blood cancer cells

Oncogene, 2019-07, Vol.38 (30), p.5890-5904

2019

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GZ17-6.02 interacts with proteasome inhibitors to kill multiple myeloma cells

Oncotarget, 2024-03, Vol.15 (1), p.159-174

2024

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[pemetrexed + sildenafil], via autophagy-dependent HDAC downregulation, enhances the immunotherapy response of NSCLC cells

Cancer biology & therapy, 2017-09, Vol.18 (9), p.705-714

2017

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GZ17‐6.02 initiates DNA damage causing autophagosome‐dependent HDAC degradation resulting in enhanced anti‐PD1 checkpoint inhibitory antibody efficacy

Journal of cellular physiology, 2020-11, Vol.235 (11), p.8098-8113

2020

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Curcumin interacts with sildenafil to kill GI tumor cells via endoplasmic reticulum stress and reactive oxygen/ nitrogen species

Oncotarget, 2017-11, Vol.8 (59), p.99451-99469

2017

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GZ17-6.02 interacts with bexarotene to kill mycosis fungoides cells

Oncotarget, 2024-02, Vol.15 (1), p.124-133

2024

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PDE5 inhibitors enhance the lethality of pemetrexed through inhibition of multiple chaperone proteins and via the actions of cyclic GMP and nitric oxide

Oncotarget, 2017-01, Vol.8 (1), p.1449-1468

2017

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Fingolimod augments Pemetrexed killing of non-small cell lung cancer and overcomes resistance to ERBB inhibition

Cancer biology & therapy, 2019-05, Vol.20 (5), p.597-607

2019

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Regulation of OSU-03012 toxicity by ER stress proteins and ER stress-inducing drugs

Molecular cancer therapeutics, 2014-10, Vol.13 (10), p.2384-2398

2014

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OSU-03012 and Viagra Treatment Inhibits the Activity of Multiple Chaperone Proteins and Disrupts the Blood-Brain Barrier: Implications for Anti-Cancer Therapies

GZ17-6.02 kills prostate cancer cells in vitro and in vivo

Axitinib and HDAC Inhibitors Interact to Kill Sarcoma Cells

The Lethality of [Pazopanib + HDAC Inhibitors] Is Enhanced by Neratinib

Fingolimod Augments Monomethylfumarate Killing of GBM Cells

The afatinib resistance of in vivo generated H1975 lung cancer cell clones is mediated by SRC/ERBB3/c-KIT/c-MET compensatory survival signaling

The role of cell signaling in the crosstalk between autophagy and apoptosis in the regulation of tumor cell survival in response to sorafenib and neratinib

HDAC inhibitors enhance the immunotherapy response of melanoma cells

Formulated Curcumin Prevents Paclitaxel-Induced Peripheral Neuropathy through Reduction in Neuroinflammation by Modulation of α7 Nicotinic Acetylcholine Receptors

A Fenofibrate Diet Prevents Paclitaxel-Induced Peripheral Neuropathy in Mice

Corrigendum: Fingolimod Augments Monomethylfumarate Killing of GBM Cells

AR12 (OSU-03012) suppresses GRP78 expression and inhibits SARS-CoV-2 replication

Differential regulation of autophagy and cell viability by ceramide species

The multi-kinase inhibitor lenvatinib interacts with the HDAC inhibitor entinostat to kill liver cancer cells

Autophagy as a therapeutic mechanism to kill drug-resistant cancer cells

(Curcumin+sildenafil) enhances the efficacy of 5FU and anti‐PD1 therapies in vivo

Neratinib inhibits Hippo/YAP signaling, reduces mutant K-RAS expression, and kills pancreatic and blood cancer cells

GZ17-6.02 interacts with proteasome inhibitors to kill multiple myeloma cells

[pemetrexed + sildenafil], via autophagy-dependent HDAC downregulation, enhances the immunotherapy response of NSCLC cells

GZ17‐6.02 initiates DNA damage causing autophagosome‐dependent HDAC degradation resulting in enhanced anti‐PD1 checkpoint inhibitory antibody efficacy

Curcumin interacts with sildenafil to kill GI tumor cells via endoplasmic reticulum stress and reactive oxygen/ nitrogen species

GZ17-6.02 interacts with bexarotene to kill mycosis fungoides cells

PDE5 inhibitors enhance the lethality of pemetrexed through inhibition of multiple chaperone proteins and via the actions of cyclic GMP and nitric oxide

Fingolimod augments Pemetrexed killing of non-small cell lung cancer and overcomes resistance to ERBB inhibition

Regulation of OSU-03012 toxicity by ER stress proteins and ER stress-inducing drugs

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