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Cancer acidity: an ultimate frontier of tumor immune escape and a novel target of immunomodulation

Seminars in cancer biology, 2017-04, Vol.43, p.74-89

2017

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Phenotype, function and clinical implications of myeloid-derived suppressor cells in cancer patients

Cancer Immunology, Immunotherapy, 2012-02, Vol.61 (2), p.255-263

2012

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Fasting-mimicking diet plus chemotherapy in breast cancer treatment

Nature communications, 2020-08, Vol.11 (1), p.4274-4274, Article 4274

2020

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Recent advances on the role of tumor exosomes in immunosuppression and disease progression

Seminars in cancer biology, 2012-08, Vol.22 (4), p.342-349

2012

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Immune surveillance properties of human NK cell-derived exosomes

The Journal of immunology (1950), 2012-09, Vol.189 (6), p.2833-2842

2012

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Potential role of HER2-overexpressing exosomes in countering trastuzumab-based therapy

Journal of cellular physiology, 2012-02, Vol.227 (2), p.658-667

2012

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Tumor-released microvesicles as vehicles of immunosuppression

Cancer research (Chicago, Ill.), 2007-04, Vol.67 (7), p.2912-2915

2007

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High levels of exosomes expressing CD63 and caveolin-1 in plasma of melanoma patients

PloS one, 2009-04, Vol.4 (4), p.e5219-e5219

2009

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Immunosuppressive circuits in tumor microenvironment and their influence on cancer treatment efficacy

Virchows Archiv : an international journal of pathology, 2019-04, Vol.474 (4), p.407-420

2019

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Identification of a New Subset of Myeloid Suppressor Cells in Peripheral Blood of Melanoma Patients With Modulation by a Granulocyte-Macrophage Colony-Stimulation Factor–Based Antitumor Vaccine

Journal of clinical oncology, 2007-06, Vol.25 (18), p.2546-2553

2007

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Pathologic complete response after neoadjuvant chemotherapy/(re)chemoradiation for pelvic relapse of rectal cancer undergoing complex pelvic surgery: more frequent than expected?

International journal of colorectal disease, 2022-10, Vol.37 (10), p.2257-2261

2022

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pH‐dependent antitumor activity of proton pump inhibitors against human melanoma is mediated by inhibition of tumor acidity

International journal of cancer, 2010-07, Vol.127 (1), p.207-219

2010

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Ipilimumab and fotemustine in patients with advanced melanoma (NIBIT-M1): an open-label, single-arm phase 2 trial

The lancet oncology, 2012-09, Vol.13 (9), p.879-886

2012

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A novel computational method for automatic segmentation, quantification and comparative analysis of immunohistochemically labeled tissue sections

BMC bioinformatics, 2018-10, Vol.19 (Suppl 10), p.357-357, Article 357

2018

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The acidity of the tumor microenvironment is a mechanism of immune escape that can be overcome by proton pump inhibitors

Oncoimmunology, 2013-01, Vol.2 (1), p.22-21

2013

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3D tumor explant as a novel platform to investigate therapeutic pathways and predictive biomarkers in cancer patients

Frontiers in immunology, 2022-12, Vol.13, p.1068091-1068091

2022

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pH regulators to target the tumor immune microenvironment in human hepatocellular carcinoma

Oncoimmunology, 2018-07, Vol.7 (7), p.e1445452-e1445452

2018

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Immunological characterization of a long-lasting response in a patient with metastatic triple-negative breast cancer treated with PD-1 and LAG-3 blockade

Scientific reports, 2024-02, Vol.14 (1), p.3379-3379, Article 3379

2024

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Alternative Activation of Human Plasmacytoid DCs In Vitro and in Melanoma Lesions: Involvement of LAG-3

Journal of investigative dermatology, 2014-07, Vol.134 (7), p.1893-1902

2014

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Salivary Cytokine Levels and Oral Mucositis in Head and Neck Cancer Patients Treated With Chemotherapy and Radiation Therapy

International journal of radiation oncology, biology, physics, 2016-12, Vol.96 (5), p.959-966

2016

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Assessing the safety, tolerability and efficacy of PLGA-based immunomodulatory nanoparticles in patients with advanced NY-ESO-1-positive cancers: a first-in-human phase I open-label dose-escalation study protocol

BMJ open, 2021-11, Vol.11 (11), p.e050725-e050725

2021

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Comprehensive genomic profiling on metastatic Melanoma: results from a network screening from 7 Italian Cancer Centres

Journal of translational medicine, 2024-01, Vol.22 (1), p.29-7, Article 29

2024

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Identification of MET and SRC Activation in Melanoma Cell Lines Showing Primary Resistance to PLX4032

Neoplasia (New York, N.Y.), 2011-12, Vol.13 (12), p.1132-IN17

2011

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A Pilot Low-Inflammatory Dietary Intervention to Reduce Inflammation and Improve Quality of Life in Patients With Familial Adenomatous Polyposis: Protocol Description and Preliminary Results

Integrative cancer therapies, 2019-05, Vol.18, p.1534735419846400-1534735419846400

2019

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Cancer acidity: an ultimate frontier of tumor immune escape and a novel target of immunomodulation

Phenotype, function and clinical implications of myeloid-derived suppressor cells in cancer patients

Fasting-mimicking diet plus chemotherapy in breast cancer treatment

Antibody-Fc/FcR Interaction on Macrophages as a Mechanism for Hyperprogressive Disease in Non-small Cell Lung Cancer Subsequent to PD-1/PD-L1 Blockade

Recent advances on the role of tumor exosomes in immunosuppression and disease progression

Immune surveillance properties of human NK cell-derived exosomes

Potential role of HER2-overexpressing exosomes in countering trastuzumab-based therapy

Tumor-released microvesicles as vehicles of immunosuppression

High levels of exosomes expressing CD63 and caveolin-1 in plasma of melanoma patients

Immunosuppressive circuits in tumor microenvironment and their influence on cancer treatment efficacy

Identification of a New Subset of Myeloid Suppressor Cells in Peripheral Blood of Melanoma Patients With Modulation by a Granulocyte-Macrophage Colony-Stimulation Factor–Based Antitumor Vaccine

Pathologic complete response after neoadjuvant chemotherapy/(re)chemoradiation for pelvic relapse of rectal cancer undergoing complex pelvic surgery: more frequent than expected?

pH‐dependent antitumor activity of proton pump inhibitors against human melanoma is mediated by inhibition of tumor acidity

Ipilimumab and fotemustine in patients with advanced melanoma (NIBIT-M1): an open-label, single-arm phase 2 trial

A novel computational method for automatic segmentation, quantification and comparative analysis of immunohistochemically labeled tissue sections

The acidity of the tumor microenvironment is a mechanism of immune escape that can be overcome by proton pump inhibitors

3D tumor explant as a novel platform to investigate therapeutic pathways and predictive biomarkers in cancer patients

pH regulators to target the tumor immune microenvironment in human hepatocellular carcinoma

Immunological characterization of a long-lasting response in a patient with metastatic triple-negative breast cancer treated with PD-1 and LAG-3 blockade

Alternative Activation of Human Plasmacytoid DCs In Vitro and in Melanoma Lesions: Involvement of LAG-3

Salivary Cytokine Levels and Oral Mucositis in Head and Neck Cancer Patients Treated With Chemotherapy and Radiation Therapy

Assessing the safety, tolerability and efficacy of PLGA-based immunomodulatory nanoparticles in patients with advanced NY-ESO-1-positive cancers: a first-in-human phase I open-label dose-escalation study protocol

Comprehensive genomic profiling on metastatic Melanoma: results from a network screening from 7 Italian Cancer Centres

Identification of MET and SRC Activation in Melanoma Cell Lines Showing Primary Resistance to PLX4032

A Pilot Low-Inflammatory Dietary Intervention to Reduce Inflammation and Improve Quality of Life in Patients With Familial Adenomatous Polyposis: Protocol Description and Preliminary Results

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