UB Paderborn / Katalog / Suche / in CDI

1 – 25 von 33

Sortiert nach

Stabilizing the closed SARS-CoV-2 spike trimer

Nature communications, 2021-01, Vol.12 (1), p.244-244, Article 244

2021

Link zum Volltext

Verfügbarkeit prüfen

Efficacious human metapneumovirus vaccine based on AI-guided engineering of a closed prefusion trimer

Nature communications, 2024-07, Vol.15 (1), p.6270-17, Article 6270

2024

Link zum Volltext

Verfügbarkeit prüfen

Current progress in Structure-Based Rational Drug Design marks a new mindset in drug discovery

Computational and structural biotechnology journal, 2013-02, Vol.5 (6), p.e201302011, Article e201302011

2013

Link zum Volltext

Verfügbarkeit prüfen

Steering Siglec–Sialic Acid Interactions on Living Cells using Bioorthogonal Chemistry

Angewandte Chemie (International ed.), 2017-03, Vol.56 (12), p.3309-3313

International ed. in English, 2017

Link zum Volltext

Verfügbarkeit prüfen

Statin Lactonization by Uridine 5′-Diphospho-glucuronosyltransferases (UGTs)

Molecular pharmaceutics, 2015-11, Vol.12 (11), p.4048-4055

2015

Link zum Volltext

Verfügbarkeit prüfen

Discovery of Small Molecule CD40–TRAF6 Inhibitors

Journal of chemical information and modeling, 2015-02, Vol.55 (2), p.294-307

2015

Link zum Volltext

Verfügbarkeit prüfen

3D-e-Chem-VM: Structural Cheminformatics Research Infrastructure in a Freely Available Virtual Machine

Journal of chemical information and modeling, 2017-02, Vol.57 (2), p.115-121

2017

Link zum Volltext

Verfügbarkeit prüfen

RSV A2-Based Prefusion F Vaccine Candidates Induce RSV A and RSV B Cross Binding and Neutralizing Antibodies and Provide Protection against RSV A and RSV B Challenge in Preclinical Models

Vaccines (Basel), 2023-03, Vol.11 (3), p.672

2023

Link zum Volltext

Verfügbarkeit prüfen

Involvement of a Hydrophobic Pocket and Helix 11 in Determining the Modes of Action of Prenylated Flavonoids and Isoflavonoids in the Human Estrogen Receptor

Chembiochem : a European journal of chemical biology, 2015-12, Vol.16 (18), p.2668-2677

2015

Link zum Volltext

Verfügbarkeit prüfen

Snooker structure-based pharmacophore model explains differences in agonist and blocker binding to bitter receptor hTAS2R39

PloS one, 2015-03, Vol.10 (3), p.e0118200-e0118200

2015

Link zum Volltext

Verfügbarkeit prüfen

Mitochondrial ADP/ATP exchange inhibition: a novel off-target mechanism underlying ibipinabant-induced myotoxicity

Scientific reports, 2015-09, Vol.5 (1), p.14533, Article 14533

2015

Link zum Volltext

Verfügbarkeit prüfen

An Integrative Approach Combining Noncovalent Mass Spectrometry, Enzyme Kinetics and X-ray Crystallography to Decipher Tgt Protein-Protein and Protein-RNA Interaction

Journal of molecular biology, 2009-11, Vol.393 (4), p.833-847

2009

Link zum Volltext

Verfügbarkeit prüfen

Potent Inhibitors of tRNA-Guanine Transglycosylase, an Enzyme Linked to the Pathogenicity of the Shigella Bacterium: Charge-Assisted Hydrogen Bonding

Angewandte Chemie (International ed.), 2007, Vol.46 (43), p.8266-8269

2007

Link zum Volltext

Verfügbarkeit prüfen

Pharmacophore Fingerprint-Based Approach to Binding Site Subpocket Similarity and Its Application to Bioisostere Replacement

Journal of chemical information and modeling, 2012-08, Vol.52 (8), p.2031-2043

2012

Link zum Volltext

Verfügbarkeit prüfen

Statin-Induced Myopathy Is Associated with Mitochondrial Complex III Inhibition

Cell metabolism, 2015-09, Vol.22 (3), p.399-407

2015

Link zum Volltext

Verfügbarkeit prüfen

Molecular interaction fingerprint approaches for GPCR drug discovery

Current opinion in pharmacology, 2016-10, Vol.30, p.59-68

2016

Link zum Volltext

Verfügbarkeit prüfen

Universal stabilization of the influenza hemagglutinin by structure-based redesign of the pH switch regions

Proceedings of the National Academy of Sciences - PNAS, 2022-02, Vol.119 (6), p.1

2022

Link zum Volltext

Verfügbarkeit prüfen

Finding the right approach to big data-driven medicinal chemistry

Future medicinal chemistry, 2015-01, Vol.7 (10), p.1213-1216

2015

Link zum Volltext

Verfügbarkeit prüfen

Involvement of a Hydrophobic Pocket and Helix11 in Determining the Modes of Action of Prenylated Flavonoids and Isoflavonoids in the Human Estrogen Receptor

Chembiochem : a European journal of chemical biology, 2015-12, Vol.16 (18), p.2668

2015

Link zum Volltext

Verfügbarkeit prüfen

In Silico Identification and in Vitro Validation of Potential Cholestatic Compounds through 3D Ligand-Based Pharmacophore Modeling of BSEP Inhibitors

Chemical research in toxicology, 2014-05, Vol.27 (5), p.873-881

2014

Link zum Volltext

Verfügbarkeit prüfen

High-affinity inhibitors of Zymomonas mobilis tRNA-guanine transglycosylase through convergent optimization

Acta crystallographica. Section D, Biological crystallography., 2013-09, Vol.69 (9), p.1798-1807

2013

Link zum Volltext

Verfügbarkeit prüfen

From lin-Benzoguanines to lin-Benzohypoxanthines as Ligands for Zymomonas mobilis tRNA-Guanine Transglycosylase: Replacement of Protein-Ligand Hydrogen Bonding by Importing Water Clusters

Chemistry : a European journal, 2012-07, Vol.18 (30), p.9246-9257

2012

Link zum Volltext

Verfügbarkeit prüfen

Crystal Structure Analysis and in Silico pKa Calculations Suggest Strong pKa Shifts of Ligands as Driving Force for High-Affinity Binding to TGT

Chembiochem : a European journal of chemical biology, 2009-03, Vol.10 (4), p.716-727

2009

Link zum Volltext

Verfügbarkeit prüfen

High-Affinity Inhibitors of tRNA-Guanine Transglycosylase Replacing the Function of a Structural Water Cluster

Chemistry : a European journal, 2009-10, Vol.15 (41), p.10809-10817

2009

Link zum Volltext

Verfügbarkeit prüfen

1 – 25 von 33

Suche als RSS-Feed

Suchergebnisse filtern

Filter anzeigen

Nur zeigen

Geprüft (Peer-Review)
(33)
Mit Volltextzugriff
(33)

Publikationsform

Artikel
(33)

Sprache

Englisch
(32)
Japanisch
(11)
Deutsch
(3)

Erscheinungsjahr

n.n

Thema

Science & Technology
(22)
Life Sciences & Biomedicine
(15)
Ligands
(12)
Models, Molecular
(11)
Chemistry
(10)
Humans
(10)
Drug Design
(9)
Pharmacology & Pharmacy
(9)
Proteins
(9)
Binding Sites
(8)
Physical Sciences
(8)
Protein Binding
(8)
Chemistry, Medicinal
(7)
Chemistry, Multidisciplinary
(6)
Pentosyltransferases - Chemistry
(6)
Biochemistry & Molecular Biology
(5)
Crystallography, X-Ray
(5)
Molecular Docking Simulation
(5)
Pentosyltransferases - Antagonists & Inhibitors
(5)
Protein Conformation
(5)

15 weitere anzeigen...

Weniger anzeigen...

Neu hinzugefügt

... seit 7 Tagen
(1)

Menü

Weitere Dienste

Einstellungen

Stabilizing the closed SARS-CoV-2 spike trimer

Efficacious human metapneumovirus vaccine based on AI-guided engineering of a closed prefusion trimer

Current progress in Structure-Based Rational Drug Design marks a new mindset in drug discovery

Steering Siglec–Sialic Acid Interactions on Living Cells using Bioorthogonal Chemistry

Statin Lactonization by Uridine 5′-Diphospho-glucuronosyltransferases (UGTs)

Discovery of Small Molecule CD40–TRAF6 Inhibitors

3D-e-Chem-VM: Structural Cheminformatics Research Infrastructure in a Freely Available Virtual Machine

RSV A2-Based Prefusion F Vaccine Candidates Induce RSV A and RSV B Cross Binding and Neutralizing Antibodies and Provide Protection against RSV A and RSV B Challenge in Preclinical Models

Involvement of a Hydrophobic Pocket and Helix 11 in Determining the Modes of Action of Prenylated Flavonoids and Isoflavonoids in the Human Estrogen Receptor

Snooker structure-based pharmacophore model explains differences in agonist and blocker binding to bitter receptor hTAS2R39

Mitochondrial ADP/ATP exchange inhibition: a novel off-target mechanism underlying ibipinabant-induced myotoxicity

Enhancing breadth and durability of humoral immune responses in non-human primates with an adjuvanted group 1 influenza hemagglutinin stem antigen

An Integrative Approach Combining Noncovalent Mass Spectrometry, Enzyme Kinetics and X-ray Crystallography to Decipher Tgt Protein-Protein and Protein-RNA Interaction

Potent Inhibitors of tRNA-Guanine Transglycosylase, an Enzyme Linked to the Pathogenicity of the Shigella Bacterium: Charge-Assisted Hydrogen Bonding

Pharmacophore Fingerprint-Based Approach to Binding Site Subpocket Similarity and Its Application to Bioisostere Replacement

Statin-Induced Myopathy Is Associated with Mitochondrial Complex III Inhibition

Molecular interaction fingerprint approaches for GPCR drug discovery

Universal stabilization of the influenza hemagglutinin by structure-based redesign of the pH switch regions

Finding the right approach to big data-driven medicinal chemistry

Involvement of a Hydrophobic Pocket and Helix11 in Determining the Modes of Action of Prenylated Flavonoids and Isoflavonoids in the Human Estrogen Receptor

In Silico Identification and in Vitro Validation of Potential Cholestatic Compounds through 3D Ligand-Based Pharmacophore Modeling of BSEP Inhibitors

High-affinity inhibitors of Zymomonas mobilis tRNA-guanine transglycosylase through convergent optimization

From lin-Benzoguanines to lin-Benzohypoxanthines as Ligands for Zymomonas mobilis tRNA-Guanine Transglycosylase: Replacement of Protein-Ligand Hydrogen Bonding by Importing Water Clusters

Crystal Structure Analysis and in Silico pKa Calculations Suggest Strong pKa Shifts of Ligands as Driving Force for High-Affinity Binding to TGT

High-Affinity Inhibitors of tRNA-Guanine Transglycosylase Replacing the Function of a Structural Water Cluster

Suchergebnisse filtern