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Taccalonolide Binding to Tubulin Imparts Microtubule Stability and Potent In Vivo Activity

Cancer research (Chicago, Ill.), 2013-11, Vol.73 (22), p.6780-6792

2013

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Abstract P5-08-06: Differential effects of eribulin on key transcription factors snail and slug

Cancer research (Chicago, Ill.), 2019-02, Vol.79 (4_Supplement), p.P5-P5-08-06

2019

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Abstract P5-04-04: Eribulin differentially disrupts TGF-β signaling pathway in BT-549 and HCC1937 breast cancer cell lines

Cancer research (Chicago, Ill.), 2018-02, Vol.78 (4_Supplement), p.P5-P5-04-04

2018

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Abstract P4-04-04: Eribulin impairs TGF-β type I receptor localization and signaling in BT-549 cells

Cancer research (Chicago, Ill.), 2017-02, Vol.77 (4_Supplement), p.P4-P4-04-04

2017

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Abstract P2-13-01: Differential efficacies of DNA damaging agents in basal-like TNBC subtypes

Cancer research (Chicago, Ill.), 2018-02, Vol.78 (4_Supplement), p.P2-P2-13-01

2018

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Abstract P6-13-07: The taccalonolides are novel microtubule stabilizers that covalently bind tubulin and have in vivo efficacy in drug resistant tumors

Cancer research (Chicago, Ill.), 2016-02, Vol.76 (4_Supplement), p.P6-P6-13-07

2016

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Abstract P5-03-08: Eribulin impairs the transport of TGF-β type I receptor leading to inhibition of downstream non-canonical TGF-β signaling necessary for cancer metastasis and survival

Cancer research (Chicago, Ill.), 2016-02, Vol.76 (4_Supplement), p.P5-P5-03-08

2016

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Abstract P5-03-04: Identification of compounds from natural sources with selective activity against triple-negative breast cancer molecular subtypes

Cancer research (Chicago, Ill.), 2016-02, Vol.76 (4_Supplement), p.P5-P5-03-04

2016

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Abstract P5-03-09: Eribulin affects E-cadherin localization consistent with a reversal of the epithelial-to-mesenchymal transition

Cancer research (Chicago, Ill.), 2016-02, Vol.76 (4_Supplement), p.P5-P5-03-09

2016

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Abstract P1-15-07: The neuroprotective aminopropyl carbazole, P7C3-A20, prevents paclitaxel-induced pain

Cancer research (Chicago, Ill.), 2016-02, Vol.76 (4_Supplement), p.P1-P1-15-07

2016

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Design, synthesis and biological evaluation of new bulky acyloxy taccalonolides as potent microtubule stabilizers

Planta medica, 2015, Vol.81 (11)

2015

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Design, synthesis and biological evaluation of new bulky acyloxy taccalonolides as potent microtubule stabilizers

Planta medica, 2015, Vol.81 (11)

2015

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Abstract P5-04-18: Extracts derived from fungi and plants demonstrate specificity for subtyptes of triple negative breast cancer

Cancer research (Chicago, Ill.), 2016-02, Vol.76 (4_Supplement), p.P5-P5-04-18

2016

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Identifying specific inhibitors of triple-negative breast cancer subtypes

Planta medica, 2016, Vol.81 (S 01), p.S1-S381

2016

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Novel Retro-Chalcone Derivatives Isolated from Tacca chantrieri

Planta medica, 2013, Vol.79 (10)

2013

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Antimalarial metabolites from Buxus sempervirens

Planta medica, 2015, Vol.81 (11)

2015

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Utilizing differential cytotoxicity screening to identify lead compounds for rare adult and pediatric tumors

Planta medica, 2015, Vol.81 (11)

2015

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Structure-activity relationships study of new microtubule stabilizing taccalonolides

Planta medica, 2012, Vol.78 (11)

2012

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Epoxidation at C22-C23 significantly increases the potency of microtubule stabilizing taccalonolides

Planta medica, 2012, Vol.78 (11)

2012

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Potent new microtubule stabilizers with unique biochemical and cellular effects show promise for cancer treatment

Planta medica, 2012, Vol.78 (11)

2012

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The Bat Flower: Ying and Yang of Microtubule Targeting Agents

Planta medica, 2013, Vol.79 (10)

2013

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The taccalonolides are a novel class of microtubule stabilizers that circumvent clinically relevant taxane resistance mechanisms

Cancer research (Chicago, Ill.), 2009-01, Vol.69 (2_Supplement), p.2142

2009

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Mapping chromatin structure in vivo using DNA methyltransferases

Methods (San Diego, Calif.), 2004-05, Vol.33 (1), p.68-80

2004

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Microtubule-Targeting Drugs: More than Antimitotics

Journal of natural products (Washington, D.C.), 2019-03, Vol.82 (3), p.680-685

2019

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Eribulin mesylate: mechanism of action of a unique microtubule-targeting agent

Clinical cancer research, 2015-06, Vol.21 (11), p.2445-2452

2015

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Taccalonolide Binding to Tubulin Imparts Microtubule Stability and Potent In Vivo Activity

Abstract P5-08-06: Differential effects of eribulin on key transcription factors snail and slug

Abstract P5-04-04: Eribulin differentially disrupts TGF-β signaling pathway in BT-549 and HCC1937 breast cancer cell lines

Abstract P4-04-04: Eribulin impairs TGF-β type I receptor localization and signaling in BT-549 cells

Abstract P2-13-01: Differential efficacies of DNA damaging agents in basal-like TNBC subtypes

Abstract P6-13-07: The taccalonolides are novel microtubule stabilizers that covalently bind tubulin and have in vivo efficacy in drug resistant tumors

Abstract P5-03-08: Eribulin impairs the transport of TGF-β type I receptor leading to inhibition of downstream non-canonical TGF-β signaling necessary for cancer metastasis and survival

Abstract P5-03-04: Identification of compounds from natural sources with selective activity against triple-negative breast cancer molecular subtypes

Abstract P5-03-09: Eribulin affects E-cadherin localization consistent with a reversal of the epithelial-to-mesenchymal transition

Abstract P1-15-07: The neuroprotective aminopropyl carbazole, P7C3-A20, prevents paclitaxel-induced pain

Design, synthesis and biological evaluation of new bulky acyloxy taccalonolides as potent microtubule stabilizers

Design, synthesis and biological evaluation of new bulky acyloxy taccalonolides as potent microtubule stabilizers

Abstract P5-04-18: Extracts derived from fungi and plants demonstrate specificity for subtyptes of triple negative breast cancer

Identifying specific inhibitors of triple-negative breast cancer subtypes

Novel Retro-Chalcone Derivatives Isolated from Tacca chantrieri

Antimalarial metabolites from Buxus sempervirens

Utilizing differential cytotoxicity screening to identify lead compounds for rare adult and pediatric tumors

Structure-activity relationships study of new microtubule stabilizing taccalonolides

Epoxidation at C22-C23 significantly increases the potency of microtubule stabilizing taccalonolides

Potent new microtubule stabilizers with unique biochemical and cellular effects show promise for cancer treatment

The Bat Flower: Ying and Yang of Microtubule Targeting Agents

The taccalonolides are a novel class of microtubule stabilizers that circumvent clinically relevant taxane resistance mechanisms

Mapping chromatin structure in vivo using DNA methyltransferases

Microtubule-Targeting Drugs: More than Antimitotics

Eribulin mesylate: mechanism of action of a unique microtubule-targeting agent

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