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The Hedgehog signal transduction network

Science signaling, 2012-10, Vol.5 (246), p.re6

2012

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Pathways of signal transduction employed by vertebrate Hedgehogs

Biochemical journal, 2007-05, Vol.403 (3), p.369-379

2007

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Hedgehog proteins activate pro-angiogenic responses in endothelial cells through non-canonical signaling pathways

Cell cycle (Georgetown, Tex.), 2010-02, Vol.9 (3), p.570-579

2010

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Activation of Heterotrimeric G Proteins by Smoothened

Proceedings of the National Academy of Sciences - PNAS, 2006-08, Vol.103 (33), p.12607-12612

2006

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Cell cycle- and cancer-associated gene networks activated by Dsg2: evidence of cystatin A deregulation and a potential role in cell-cell adhesion

PloS one, 2015-03, Vol.10 (3), p.e0120091-e0120091

2015

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Annotation and automated segmentation of single-molecule localisation microscopy data

Journal of microscopy (Oxford), 2024-08

2024

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Receptors coupled to heterotrimeric G proteins of the G12 family

Trends in pharmacological sciences (Regular ed.), 2005-03, Vol.26 (3), p.146-154

2005

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Early mitochondrial dysfunction in electron transfer activity and reactive oxygen species generation after cardiac arrest

Critical care medicine, 2008-11, Vol.36 (11), p.S447-S453

2008

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Autophagic Flux Is Regulated by Interaction Between the C-terminal Domain of PATCHED1 and ATG101

Molecular cancer research, 2018-05, Vol.16 (5), p.909-919

2018

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Patched-1 Proapoptotic Activity Is Downregulated by Modification of K1413 by the E3 Ubiquitin-Protein Ligase Itchy Homolog

Molecular and cellular biology, 2014-10, Vol.34 (20), p.3855-3866

2014

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Trop-2 is up-regulated in invasive prostate cancer and displaces FAK from focal contacts

Oncotarget, 2015-06, Vol.6 (16), p.14318-14328

2015

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Cholesterol and its derivatives in Sonic Hedgehog signaling and cancer

Current opinion in pharmacology, 2012-12, Vol.12 (6), p.736-741

Riobo, Natalia A

2012

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Role of Hedgehog Signaling in Breast Cancer: Pathogenesis and Therapeutics

Cells (Basel, Switzerland), 2019-04, Vol.8 (4), p.375

2019

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Long non-coding RNA HOTAIR induces GLI2 expression through Notch signalling in systemic sclerosis dermal fibroblasts

Arthritis research & therapy, 2020-12, Vol.22 (1), p.286-286, Article 286

2020

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Hedgehog Signal Transduction: Signal Integration and Cross Talk in Development and Cancer

Cell cycle (Georgetown, Tex.), 2006-08, Vol.5 (15), p.1612-1615

2006

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PTCHD1 Binds Cholesterol but Not Sonic Hedgehog, Suggesting a Distinct Cellular Function

International journal of molecular sciences, 2023-01, Vol.24 (3), p.2682

2023

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Noncanonical Hedgehog Signaling

Hedgehog Signaling, 2012, Vol.88, p.55-72

2012

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Heterotrimeric Gi Proteins Link Hedgehog Signaling to Activation of Rho Small GTPases to Promote Fibroblast Migration

The Journal of biological chemistry, 2011-06, Vol.286 (22), p.19589-19596

2011

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Evaluating the Activity of Smoothened Toward G Proteins Using [³⁵S]Guanosine 5'-(3-O-thio)triphosphate ([³⁵S]GTPγS)

Methods in molecular biology (Clifton, N.J.), 2015, Vol.1322, p.35

2015

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Overexpression of Desmoglein 2 in a Mouse Model of Gorlin Syndrome Enhances Spontaneous Basal Cell Carcinoma Formation through STAT3-Mediated Gli1 Expression

Journal of investigative dermatology, 2019-02, Vol.139 (2), p.300-307

2019

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Phosphoinositide 3-Kinase and Akt Are Essential for Sonic Hedgehog Signaling

Proceedings of the National Academy of Sciences - PNAS, 2006-03, Vol.103 (12), p.4505-4510

2006

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Overlap in signaling between Smoothened and the α subunit of the heterotrimeric G protein G13

PloS one, 2018-05, Vol.13 (5), p.e0197442-e0197442

2018

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Methods for Detection of Ptc1-Driven LacZ Expression in Adult Mouse Skin

Methods in molecular biology (Clifton, N.J.), 2015, Vol.1322, p.167

2015

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Ubiquitin-protein ligase Ubr5 cooperates with hedgehog signalling to promote skeletal tissue homeostasis

PLoS genetics, 2021-04, Vol.17 (4), p.e1009275

2021

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Smoothened is a fully competent activator of the heterotrimeric G protein G(i)

Molecular pharmacology, 2013-03, Vol.83 (3), p.691-697

2013

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The Hedgehog signal transduction network

Pathways of signal transduction employed by vertebrate Hedgehogs

Hedgehog proteins activate pro-angiogenic responses in endothelial cells through non-canonical signaling pathways

Activation of Heterotrimeric G Proteins by Smoothened

Cell cycle- and cancer-associated gene networks activated by Dsg2: evidence of cystatin A deregulation and a potential role in cell-cell adhesion

Annotation and automated segmentation of single-molecule localisation microscopy data

Receptors coupled to heterotrimeric G proteins of the G12 family

Early mitochondrial dysfunction in electron transfer activity and reactive oxygen species generation after cardiac arrest

Autophagic Flux Is Regulated by Interaction Between the C-terminal Domain of PATCHED1 and ATG101

Patched-1 Proapoptotic Activity Is Downregulated by Modification of K1413 by the E3 Ubiquitin-Protein Ligase Itchy Homolog

Trop-2 is up-regulated in invasive prostate cancer and displaces FAK from focal contacts

Cholesterol and its derivatives in Sonic Hedgehog signaling and cancer

Role of Hedgehog Signaling in Breast Cancer: Pathogenesis and Therapeutics

Long non-coding RNA HOTAIR induces GLI2 expression through Notch signalling in systemic sclerosis dermal fibroblasts

Hedgehog Signal Transduction: Signal Integration and Cross Talk in Development and Cancer

PTCHD1 Binds Cholesterol but Not Sonic Hedgehog, Suggesting a Distinct Cellular Function

Noncanonical Hedgehog Signaling

Heterotrimeric Gi Proteins Link Hedgehog Signaling to Activation of Rho Small GTPases to Promote Fibroblast Migration

Evaluating the Activity of Smoothened Toward G Proteins Using [³⁵S]Guanosine 5'-(3-O-thio)triphosphate ([³⁵S]GTPγS)

Overexpression of Desmoglein 2 in a Mouse Model of Gorlin Syndrome Enhances Spontaneous Basal Cell Carcinoma Formation through STAT3-Mediated Gli1 Expression

Phosphoinositide 3-Kinase and Akt Are Essential for Sonic Hedgehog Signaling

Overlap in signaling between Smoothened and the α subunit of the heterotrimeric G protein G13

Methods for Detection of Ptc1-Driven LacZ Expression in Adult Mouse Skin

Ubiquitin-protein ligase Ubr5 cooperates with hedgehog signalling to promote skeletal tissue homeostasis

Smoothened is a fully competent activator of the heterotrimeric G protein G(i)

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