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In vivo generation of neurotoxic prion protein: role for hsp70 in accumulation of misfolded isoforms

PLoS genetics, 2009-06, Vol.5 (6), p.e1000507-e1000507

2009

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Identification of potential pathways and biomarkers linked to progression in ALS

Annals of clinical and translational neurology, 2023-02, Vol.10 (2), p.150-165

2023

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Bringing Light to Transcription: The Optogenetics Repertoire

Frontiers in genetics, 2018-11, Vol.9, p.518-518

2018

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NCBP2 modulates neurodevelopmental defects of the 3q29 deletion in Drosophila and Xenopus laevis models

PLoS genetics, 2020-02, Vol.16 (2), p.e1008590

2020

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Engineered Hsp70 chaperones prevent Aβ42-induced memory impairments in a Drosophila model of Alzheimer's disease

Scientific reports, 2018-07, Vol.8 (1), p.9915-14, Article 9915

2018

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Insights from Drosophila on Aβ- and tau-induced mitochondrial dysfunction: mechanisms and tools

Frontiers in neuroscience, 2023-04, Vol.17, p.1184080-1184080

2023

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TDP-35, a truncated fragment of TDP-43, induces dose-dependent toxicity and apoptosis in flies

Neural regeneration research, 2022-11, Vol.17 (11), p.2441-2442

2022

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Molecular, functional, and pathological aspects of TDP-43 fragmentation

iScience, 2021-05, Vol.24 (5), p.102459-102459, Article 102459

2021

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Amyloid fibril proteomics of AD brains reveals modifiers of aggregation and toxicity

Molecular neurodegeneration, 2023-09, Vol.18 (1), p.61-61, Article 61

2023

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PhotoGal4: A Versatile Light-Dependent Switch for Spatiotemporal Control of Gene Expression in Drosophila Explants

iScience, 2020-07, Vol.23 (7), p.101308-101308, Article 101308

2020

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Combined pharmacological induction of Hsp70 suppresses prion protein neurotoxicity in Drosophila

PloS one, 2014-02, Vol.9 (2), p.e88522

2014

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secHsp70 as a tool to approach amyloid-β42 and other extracellular amyloids

Fly (Austin, Tex.), 2017-07, Vol.11 (3), p.179-184

2017

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Modeling the complex pathology of Alzheimer's disease in Drosophila

Experimental neurology, 2015-12, Vol.274 (Pt A), p.58-71

2015

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The ER stress factor XBP1s prevents amyloid-β neurotoxicity

Human molecular genetics, 2011-06, Vol.20 (11), p.2144-2160

2011

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Differential Activation of the ER Stress Factor XBP1 by Oligomeric Assemblies

Neurochemical research, 2012-08, Vol.37 (8), p.1707-1717

2012

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Aß40 displays amyloidogenic properties in the non-transgenic mouse brain but does not exacerbate Aß42 toxicity in Drosophila

Alzheimer's research & therapy, 2020-10, Vol.12 (1), p.132-12, Article 132

2020

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Drosophila models of prionopathies: insight into prion protein function, transmission, and neurotoxicity

Current opinion in genetics & development, 2017-06, Vol.44, p.141-148

2017

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Lmx1a is required for the development of the ovarian stem cell niche in Drosophila

Development (Cambridge), 2018-04, Vol.145 (8), p.dev163394-dev163394

2018

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Holdase activity of secreted Hsp70 masks amyloid-β42 neurotoxicity in Drosophila

Proceedings of the National Academy of Sciences - PNAS, 2016-08, Vol.113 (35), p.E5212-E5221

2016

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Holdase activity of secreted Hsp70 masks amyloid- beta 42 neurotoxicity in Drosophila

Proceedings of the National Academy of Sciences - PNAS, 2016-08, Vol.113 (35), p.E5212-E5212

2016

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Drosophila models of proteinopathies: the little fly that could

Current pharmaceutical design, 2012-03, Vol.18 (8), p.1108

2012

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Protein arginine methyltransferase 1 and 8 interact with FUS to modify its sub-cellular distribution and toxicity in vitro and in vivo

PloS one, 2013-04, Vol.8 (4), p.e61576

2013

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Anti-Aβ single-chain variable fragment antibodies restore memory acquisition in a Drosophila model of Alzheimer's disease

Scientific reports, 2017-09, Vol.7 (1), p.11268-13, Article 11268

2017

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KCNC3R420H , a K+ channel mutation causative in spinocerebellar ataxia 13 displays aberrant intracellular trafficking

Neurobiology of disease, 2014-11, Vol.71, p.270-279

2014

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In vivo generation of neurotoxic prion protein: role for hsp70 in accumulation of misfolded isoforms

Identification of potential pathways and biomarkers linked to progression in ALS

Bringing Light to Transcription: The Optogenetics Repertoire

NCBP2 modulates neurodevelopmental defects of the 3q29 deletion in Drosophila and Xenopus laevis models

Engineered Hsp70 chaperones prevent Aβ42-induced memory impairments in a Drosophila model of Alzheimer's disease

Insights from Drosophila on Aβ- and tau-induced mitochondrial dysfunction: mechanisms and tools

TDP-35, a truncated fragment of TDP-43, induces dose-dependent toxicity and apoptosis in flies

Molecular, functional, and pathological aspects of TDP-43 fragmentation

Amyloid fibril proteomics of AD brains reveals modifiers of aggregation and toxicity

PhotoGal4: A Versatile Light-Dependent Switch for Spatiotemporal Control of Gene Expression in Drosophila Explants

A KCNC3 mutation causes a neurodevelopmental, non-progressive SCA13 subtype associated with dominant negative effects and aberrant EGFR trafficking

Combined pharmacological induction of Hsp70 suppresses prion protein neurotoxicity in Drosophila

secHsp70 as a tool to approach amyloid-β42 and other extracellular amyloids

Modeling the complex pathology of Alzheimer's disease in Drosophila

The ER stress factor XBP1s prevents amyloid-β neurotoxicity

Differential Activation of the ER Stress Factor XBP1 by Oligomeric Assemblies

Aß40 displays amyloidogenic properties in the non-transgenic mouse brain but does not exacerbate Aß42 toxicity in Drosophila

Drosophila models of prionopathies: insight into prion protein function, transmission, and neurotoxicity

Lmx1a is required for the development of the ovarian stem cell niche in Drosophila

Holdase activity of secreted Hsp70 masks amyloid-β42 neurotoxicity in Drosophila

Holdase activity of secreted Hsp70 masks amyloid- beta 42 neurotoxicity in Drosophila

Drosophila models of proteinopathies: the little fly that could

Protein arginine methyltransferase 1 and 8 interact with FUS to modify its sub-cellular distribution and toxicity in vitro and in vivo

Anti-Aβ single-chain variable fragment antibodies restore memory acquisition in a Drosophila model of Alzheimer's disease

KCNC3R420H , a K+ channel mutation causative in spinocerebellar ataxia 13 displays aberrant intracellular trafficking

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