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Engineering bacteria for diagnostic and therapeutic applications

Nature reviews. Microbiology, 2018-04, Vol.16 (4), p.214-225

2018

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Engineered bacteria can function in the mammalian gut long-term as live diagnostics of inflammation

Nature biotechnology, 2017-07, Vol.35 (7), p.653-658

2017

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Membrane-Wrapping Contributions to Malaria Parasite Invasion of the Human Erythrocyte

Biophysical journal, 2014-07, Vol.107 (1), p.43-54

2014

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Bacterial variability in the mammalian gut captured by a single-cell synthetic oscillator

Nature communications, 2019-10, Vol.10 (1), p.4665-12, Article 4665

2019

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Interaction between Plasmodium falciparum Apical Membrane Antigen 1 and the Rhoptry Neck Protein Complex Defines a Key Step in the Erythrocyte Invasion Process of Malaria Parasites

The Journal of biological chemistry, 2010-05, Vol.285 (19), p.14815-14822

2010

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Super-resolution dissection of coordinated events during malaria parasite invasion of the human erythrocyte

Cell host & microbe, 2011-01, Vol.9 (1), p.9-20

2011

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Isolation of viable Plasmodium falciparum merozoites to define erythrocyte invasion events and advance vaccine and drug development

Proceedings of the National Academy of Sciences - PNAS, 2010-08, Vol.107 (32), p.14378-14383

2010

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An EGF-like protein forms a complex with PfRh5 and is required for invasion of human erythrocytes by Plasmodium falciparum

PLoS pathogens, 2011-09, Vol.7 (9), p.e1002199-e1002199

2011

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Biosynthesis, Localization, and Macromolecular Arrangement of the Plasmodium falciparum Translocon of Exported Proteins (PTEX)

The Journal of biological chemistry, 2012-03, Vol.287 (11), p.7871-7884

2012

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Achieving spatially precise diagnosis and therapy in the mammalian gut using synthetic microbial gene circuits

Frontiers in bioengineering and biotechnology, 2022-09, Vol.10, p.959441-959441

2022

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Apoptosis is triggered when prosurvival Bcl-2 proteins cannot restrain Bax

Proceedings of the National Academy of Sciences - PNAS, 2008-11, Vol.105 (47), p.18081-18087

2008

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Author Correction: Bacterial variability in the mammalian gut captured by a single-cell synthetic oscillator

Nature communications, 2021-03, Vol.12 (1), p.1818-1818, Article 1818

2021

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Vaccination with conserved regions of erythrocyte-binding antigens induces neutralizing antibodies against multiple strains of Plasmodium falciparum

PloS one, 2013-09, Vol.8 (9), p.e72504

2013

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Spatial localisation of actin filaments across developmental stages of the malaria parasite

PloS one, 2012-02, Vol.7 (2), p.e32188-e32188

2012

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Engineered Interspecies Amino Acid Cross-Feeding Increases Population Evenness in a Synthetic Bacterial Consortium

mSystems, 2019-08, Vol.4 (4)

2019

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Subcompartmentalisation of proteins in the rhoptries correlates with ordered events of erythrocyte invasion by the blood stage malaria parasite

PloS one, 2012-09, Vol.7 (9), p.e46160-e46160

2012

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Cryo-electron tomography reveals four-membrane architecture of the Plasmodium apicoplast

Malaria journal, 2013-01, Vol.12 (1), p.25-25, Article 25

2013

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Plasmodium falciparum merozoite invasion is inhibited by antibodies that target the PfRh2a and b binding domains

PLoS pathogens, 2011-06, Vol.7 (6), p.e1002075

2011

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Synthetic Gene Circuits Enable Systems-Level Biosensor Trigger Discovery at the Host-Microbe Interface

mSystems, 2019-06, Vol.4 (4)

2019

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Minimal requirements for actin filament disassembly revealed by structural analysis of malaria parasite actin-depolymerizing factor 1

Proceedings of the National Academy of Sciences - PNAS, 2011-06, Vol.108 (24), p.9869-9874

2011

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Malaria Parasite Invasion: Achieving Superb Resolution

Cell host & microbe, 2017-03, Vol.21 (3), p.294-296

2017

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A 3D-printed flow-cell for on-grid purification of electron microscopy samples directly from lysate

Journal of structural biology, 2023-09, Vol.215 (3), p.107999-107999, Article 107999

2023

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The Plasmodium falciparum parasitophorous vacuole protein P113 interacts with the parasite protein export machinery and maintains normal vacuole architecture

Molecular microbiology, 2022-05, Vol.117 (5), p.1245-1262

2022

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Electron tomography of Plasmodium falciparum merozoites reveals core cellular events that underpin erythrocyte invasion

Cellular microbiology, 2013-09, Vol.15 (9), p.1457-1472

2013

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Localisation-based imaging of malarial antigens during erythrocyte entry reaffirms a role for AMA1 but not MTRAP in invasion

Journal of cell science, 2016-01, Vol.129 (1), p.228-242

2016

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Engineering bacteria for diagnostic and therapeutic applications

Engineered bacteria can function in the mammalian gut long-term as live diagnostics of inflammation

Membrane-Wrapping Contributions to Malaria Parasite Invasion of the Human Erythrocyte

Bacterial variability in the mammalian gut captured by a single-cell synthetic oscillator

Interaction between Plasmodium falciparum Apical Membrane Antigen 1 and the Rhoptry Neck Protein Complex Defines a Key Step in the Erythrocyte Invasion Process of Malaria Parasites

Super-resolution dissection of coordinated events during malaria parasite invasion of the human erythrocyte

Isolation of viable Plasmodium falciparum merozoites to define erythrocyte invasion events and advance vaccine and drug development

An EGF-like protein forms a complex with PfRh5 and is required for invasion of human erythrocytes by Plasmodium falciparum

Biosynthesis, Localization, and Macromolecular Arrangement of the Plasmodium falciparum Translocon of Exported Proteins (PTEX)

Achieving spatially precise diagnosis and therapy in the mammalian gut using synthetic microbial gene circuits

Apoptosis is triggered when prosurvival Bcl-2 proteins cannot restrain Bax

Author Correction: Bacterial variability in the mammalian gut captured by a single-cell synthetic oscillator

Vaccination with conserved regions of erythrocyte-binding antigens induces neutralizing antibodies against multiple strains of Plasmodium falciparum

Spatial localisation of actin filaments across developmental stages of the malaria parasite

Engineered Interspecies Amino Acid Cross-Feeding Increases Population Evenness in a Synthetic Bacterial Consortium

Subcompartmentalisation of proteins in the rhoptries correlates with ordered events of erythrocyte invasion by the blood stage malaria parasite

Cryo-electron tomography reveals four-membrane architecture of the Plasmodium apicoplast

Plasmodium falciparum merozoite invasion is inhibited by antibodies that target the PfRh2a and b binding domains

Synthetic Gene Circuits Enable Systems-Level Biosensor Trigger Discovery at the Host-Microbe Interface

Minimal requirements for actin filament disassembly revealed by structural analysis of malaria parasite actin-depolymerizing factor 1

Malaria Parasite Invasion: Achieving Superb Resolution

A 3D-printed flow-cell for on-grid purification of electron microscopy samples directly from lysate

The Plasmodium falciparum parasitophorous vacuole protein P113 interacts with the parasite protein export machinery and maintains normal vacuole architecture

Electron tomography of Plasmodium falciparum merozoites reveals core cellular events that underpin erythrocyte invasion

Localisation-based imaging of malarial antigens during erythrocyte entry reaffirms a role for AMA1 but not MTRAP in invasion

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