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Optimization of a Collagen-Targeted PET Probe for Molecular Imaging of Pulmonary Fibrosis

Journal of Nuclear Medicine, 2017-12, Vol.58 (12), p.1991-1996

2017

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Type I collagen-targeted PET probe for pulmonary fibrosis detection and staging in preclinical models

Science translational medicine, 2017-04, Vol.9 (384)

2017

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Fragment-based screening of programmed death ligand 1 (PD-L1)

Bioorganic & medicinal chemistry letters, 2019-03, Vol.29 (6), p.786-790

2019

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Fragment-Based Discovery of Small Molecules Bound to T‑Cell Immunoglobulin and Mucin Domain-Containing Molecule 3 (TIM-3)

Journal of medicinal chemistry, 2021-10, Vol.64 (19), p.14757-14772

2021

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Discovery of Potent Orally Bioavailable WD Repeat Domain 5 (WDR5) Inhibitors Using a Pharmacophore-Based Optimization

Journal of medicinal chemistry, 2022-04, Vol.65 (8), p.6287-6312

2022

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Multisite Thrombus Imaging and Fibrin Content Estimation With a Single Whole-Body PET Scan in Rats

Arteriosclerosis, thrombosis, and vascular biology, 2015-10, Vol.35 (10), p.2114-2121

2015

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3D molecular MR imaging of liver fibrosis and response to rapamycin therapy in a bile duct ligation rat model

Journal of hepatology, 2015-09, Vol.63 (3), p.689-696

2015

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Structure-based discovery of potent WD repeat domain 5 inhibitors that demonstrate efficacy and safety in preclinical animal models

Proceedings of the National Academy of Sciences - PNAS, 2023-01, Vol.120 (1), p.e2211297120

2023

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Discovery and Structure-Based Optimization of Potent and Selective WD Repeat Domain 5 (WDR5) Inhibitors Containing a Dihydroisoquinolinone Bicyclic Core

Journal of medicinal chemistry, 2020-01, Vol.63 (2), p.656-675

2020

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Multimodal Molecular Imaging Reveals High Target Uptake and Specificity of 111In- and 68Ga-Labeled Fibrin-Binding Probes for Thrombus Detection in Rats

The Journal of nuclear medicine (1978), 2015-10, Vol.56 (10), p.1587-1592

2015

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Fragment-Based Screen of SARS-CoV‑2 Papain-like Protease (PLpro)

ACS medicinal chemistry letters, 2024-08, Vol.15 (8), p.1351-1357

2024

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Fibrin-Targeted PET Probes for the Detection of Thrombi

Molecular pharmaceutics, 2013-03, Vol.10 (3), p.1100-1110

2013

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Effect of Chelate Type and Radioisotope on the Imaging Efficacy of 4 Fibrin-Specific PET Probes

Journal of Nuclear Medicine, 2014-07, Vol.55 (7), p.1157-1163

2014

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In vivo molecular imaging of thrombosis and thrombolysis using a fibrin-binding positron emission tomographic probe

Circulation. Cardiovascular imaging, 2014-07, Vol.7 (4), p.697-705

2014

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Hexameric MnII Dendrimer as MRI Contrast Agent

Chemistry : a European journal, 2014-10, Vol.20 (44), p.14507-14513

2014

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Hexameric Mn(II) dendrimer as MRI contrast agent

Chemistry : a European journal, 2014-10, Vol.20 (44), p.14507-14513

2014

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Radiation Dosimetry of the Fibrin-Binding Probe ⁶⁴Cu-FBP8 and Its Feasibility for PET Imaging of Deep Vein Thrombosis and Pulmonary Embolism in Rats

The Journal of nuclear medicine (1978), 2015-07, Vol.56 (7), p.1088-1093

2015

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Hexameric Mn II Dendrimer as MRI Contrast Agent

Chemistry : a European journal, 2014-10, Vol.20 (44), p.14507-14513

2014

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Multimodal Molecular Imaging Reveals High Target Uptake and Specificity of 111 In- and 68 Ga-Labeled Fibrin-Binding Probes for Thrombus Detection in Rats

Journal of Nuclear Medicine, 2015-10, Vol.56 (10), p.1587-1592

2015

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Multimodal Molecular Imaging Reveals High Target Uptake and Specificity of sigma up 111 member of n- and sigma up 68 Gamma a-Labeled Fibrin-Binding Probes for Thrombus Detection in Rats

The Journal of nuclear medicine (1978), 2015-10, Vol.56 (10), p.1587-1587

2015

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Multimodal Molecular Imaging Reveals High Target Uptake and Specificity of ^sup 111^In- and ^sup 68^Ga-Labeled Fibrin-Binding Probes for Thrombus Detection in Rats

The Journal of nuclear medicine (1978), 2015-10, Vol.56 (10), p.1587

2015

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Discovery and Structure-Based Optimization of Potent and Selective WDR5 Inhibitors Containing a Dihydroisoquinolinone Bicyclic Core

Journal of medicinal chemistry, 2020-01, Vol.63 (2), p.656-675

2020

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Hexameric Mn super(II) Dendrimer as MRI Contrast Agent

Chemistry : a European journal, 2014-10, Vol.20 (44), p.14507-14513

2014

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Radiation Dosimetry of the Fibrin-Binding Probe ^sup 64^Cu-FBP8 and Its Feasibility for PET Imaging of Deep Vein Thrombosis and Pulmonary Embolism in Rats

The Journal of nuclear medicine (1978), 2015-07, Vol.56 (7), p.1088

2015

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Optimization of a Collagen-Targeted PET Probe for Molecular Imaging of Pulmonary Fibrosis

Type I collagen-targeted PET probe for pulmonary fibrosis detection and staging in preclinical models

Fragment-based screening of programmed death ligand 1 (PD-L1)

Fragment-Based Discovery of Small Molecules Bound to T‑Cell Immunoglobulin and Mucin Domain-Containing Molecule 3 (TIM-3)

Discovery of Potent Orally Bioavailable WD Repeat Domain 5 (WDR5) Inhibitors Using a Pharmacophore-Based Optimization

Multisite Thrombus Imaging and Fibrin Content Estimation With a Single Whole-Body PET Scan in Rats

3D molecular MR imaging of liver fibrosis and response to rapamycin therapy in a bile duct ligation rat model

Structure-based discovery of potent WD repeat domain 5 inhibitors that demonstrate efficacy and safety in preclinical animal models

Discovery and Structure-Based Optimization of Potent and Selective WD Repeat Domain 5 (WDR5) Inhibitors Containing a Dihydroisoquinolinone Bicyclic Core

Multimodal Molecular Imaging Reveals High Target Uptake and Specificity of 111In- and 68Ga-Labeled Fibrin-Binding Probes for Thrombus Detection in Rats

Fragment-Based Screen of SARS-CoV‑2 Papain-like Protease (PLpro)

Fibrin-Targeted PET Probes for the Detection of Thrombi

Effect of Chelate Type and Radioisotope on the Imaging Efficacy of 4 Fibrin-Specific PET Probes

In vivo molecular imaging of thrombosis and thrombolysis using a fibrin-binding positron emission tomographic probe

Hexameric MnII Dendrimer as MRI Contrast Agent

Hexameric Mn(II) dendrimer as MRI contrast agent

Radiation Dosimetry of the Fibrin-Binding Probe ⁶⁴Cu-FBP8 and Its Feasibility for PET Imaging of Deep Vein Thrombosis and Pulmonary Embolism in Rats

Hexameric Mn II Dendrimer as MRI Contrast Agent

Multimodal Molecular Imaging Reveals High Target Uptake and Specificity of 111 In- and 68 Ga-Labeled Fibrin-Binding Probes for Thrombus Detection in Rats

Multimodal Molecular Imaging Reveals High Target Uptake and Specificity of sigma up 111 member of n- and sigma up 68 Gamma a-Labeled Fibrin-Binding Probes for Thrombus Detection in Rats

Multimodal Molecular Imaging Reveals High Target Uptake and Specificity of ^sup 111^In- and ^sup 68^Ga-Labeled Fibrin-Binding Probes for Thrombus Detection in Rats

Discovery and Structure-Based Optimization of Potent and Selective WDR5 Inhibitors Containing a Dihydroisoquinolinone Bicyclic Core

Discovery and Structure-Based Optimization of Potent and Selective WD Repeat Domain 5 (WDR5) Inhibitors Containing a Dihydroisoquinolinone Bicyclic Core

Hexameric Mn super(II) Dendrimer as MRI Contrast Agent

Radiation Dosimetry of the Fibrin-Binding Probe ^sup 64^Cu-FBP8 and Its Feasibility for PET Imaging of Deep Vein Thrombosis and Pulmonary Embolism in Rats

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