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Heterogeneity of human bone marrow and blood natural killer cells defined by single-cell transcriptome

Nature communications, 2019-09, Vol.10 (1), p.3931-16, Article 3931

2019

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Beyond the Cell Surface: Targeting Intracellular Negative Regulators to Enhance T cell Anti-Tumor Activity

International journal of molecular sciences, 2019-11, Vol.20 (23), p.5821

2019

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STING agonist inflames the pancreatic cancer immune microenvironment and reduces tumor burden in mouse models

Journal for immunotherapy of cancer, 2019-04, Vol.7 (1), p.115-115, Article 115

2019

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Deletion of Cbl-b inhibits CD8+ T-cell exhaustion and promotes CAR T-cell function

Journal for immunotherapy of cancer, 2021-01, Vol.9 (1), p.e001688

2021

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PERK Utilizes Intrinsic Lipid Kinase Activity To Generate Phosphatidic Acid, Mediate Akt Activation, and Promote Adipocyte Differentiation

Molecular and Cellular Biology, 2012-06, Vol.32 (12), p.2268-2278

2012

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Long-term outcomes of a phase I study of agonist CD40 antibody and CTLA-4 blockade in patients with metastatic melanoma

Oncoimmunology, 2018-10, Vol.7 (10), p.e1468956-e1468956

2018

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Uncoupling Therapeutic Efficacy from Immune-Related Adverse Events in Immune Checkpoint Blockade

iScience, 2020-10, Vol.23 (10), p.101580, Article 101580

2020

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Single-cell transcriptome reveals the novel role of T-bet in suppressing the immature NK gene signature

eLife, 2020-05, Vol.9

2020

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DGKζ exerts greater control than DGKα over CD8 + T cell activity and tumor inhibition

Oncoimmunology, 2021-01, Vol.10 (1), p.1941566-1941566

2021

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Loss of PIKfyve in platelets causes a lysosomal disease leading to inflammation and thrombosis in mice

Nature communications, 2014-09, Vol.5 (1), p.4691-4691, Article 4691

2014

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Conditional Deletion of PGC-1α Results in Energetic and Functional Defects in NK Cells

iScience, 2020-09, Vol.23 (9), p.101454-101454, Article 101454

2020

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IQGAP1: Insights into the function of a molecular puppeteer

Molecular immunology, 2015-06, Vol.65 (2), p.336-349

2015

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Enhanced Effector Responses in Activated CD8+ T Cells Deficient in Diacylglycerol Kinases

Cancer research (Chicago, Ill.), 2013-06, Vol.73 (12), p.3566-3577

2013

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Frontline Science: PECAM‐1 (CD31) expression in naïve and memory, but not acutely activated, CD8+ T cells

Journal of leukocyte biology, 2018-11, Vol.104 (5), p.883-893

2018

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Regulatory T cells require TCR signaling for their suppressive function

The Journal of immunology (1950), 2015-05, Vol.194 (9), p.4362-4370

2015

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TCR signaling intensity controls CD8+ T cell responsiveness to TGF‐β

Journal of leukocyte biology, 2015-11, Vol.98 (5), p.703-712

2015

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T Cells Deficient in Diacylglycerol Kinase ζ Are Resistant to PD-1 Inhibition and Help Create Persistent Host Immunity to Leukemia

Cancer research (Chicago, Ill.), 2017-10, Vol.77 (20), p.5676-5686

2017

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Diacylglycerol kinase ζ promotes allergic airway inflammation and airway hyperresponsiveness through distinct mechanisms

Science signaling, 2019-09, Vol.12 (597)

2019

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STING Activated Tumor-Intrinsic Type I Interferon Signaling Promotes CXCR3 Dependent Antitumor Immunity in Pancreatic Cancer

Cellular and molecular gastroenterology and hepatology, 2021-01, Vol.12 (1), p.41-58

2021

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MyD88 is an essential regulator of NK cell-mediated clearance of MCMV infection

Molecular immunology, 2021-09, Vol.137, p.94-104

2021

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Decreased Diacylglycerol Metabolism Enhances ERK Activation and Augments CD8+ T Cell Functional Responses

The Journal of biological chemistry, 2011-02, Vol.286 (7), p.5254-5265

2011

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The ζ isoform of diacylglycerol kinase plays a predominant role in regulatory T cell development and TCR-mediated ras signaling

Science signaling, 2013-11, Vol.6 (303), p.ra102

2013

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The adhesion molecule PECAM-1 enhances the TGF-β-mediated inhibition of T cell function

Science signaling, 2016-03, Vol.9 (418), p.ra27

2016

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Signaling in Effector Lymphocytes: Insights toward Safer Immunotherapy

Frontiers in immunology, 2016-05, Vol.7, p.176-176

2016

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Heterogeneity of human bone marrow and blood natural killer cells defined by single-cell transcriptome

Adenosine 2A Receptor Blockade as an Immunotherapy for Treatment-Refractory Renal Cell Cancer

Beyond the Cell Surface: Targeting Intracellular Negative Regulators to Enhance T cell Anti-Tumor Activity

STING agonist inflames the pancreatic cancer immune microenvironment and reduces tumor burden in mouse models

Deletion of Cbl-b inhibits CD8+ T-cell exhaustion and promotes CAR T-cell function

PERK Utilizes Intrinsic Lipid Kinase Activity To Generate Phosphatidic Acid, Mediate Akt Activation, and Promote Adipocyte Differentiation

Long-term outcomes of a phase I study of agonist CD40 antibody and CTLA-4 blockade in patients with metastatic melanoma

Uncoupling Therapeutic Efficacy from Immune-Related Adverse Events in Immune Checkpoint Blockade

Single-cell transcriptome reveals the novel role of T-bet in suppressing the immature NK gene signature

DGKζ exerts greater control than DGKα over CD8 + T cell activity and tumor inhibition

Loss of PIKfyve in platelets causes a lysosomal disease leading to inflammation and thrombosis in mice

Conditional Deletion of PGC-1α Results in Energetic and Functional Defects in NK Cells

IQGAP1: Insights into the function of a molecular puppeteer

Enhanced Effector Responses in Activated CD8+ T Cells Deficient in Diacylglycerol Kinases

Frontline Science: PECAM‐1 (CD31) expression in naïve and memory, but not acutely activated, CD8+ T cells

Regulatory T cells require TCR signaling for their suppressive function

TCR signaling intensity controls CD8+ T cell responsiveness to TGF‐β

T Cells Deficient in Diacylglycerol Kinase ζ Are Resistant to PD-1 Inhibition and Help Create Persistent Host Immunity to Leukemia

Diacylglycerol kinase ζ promotes allergic airway inflammation and airway hyperresponsiveness through distinct mechanisms

STING Activated Tumor-Intrinsic Type I Interferon Signaling Promotes CXCR3 Dependent Antitumor Immunity in Pancreatic Cancer

MyD88 is an essential regulator of NK cell-mediated clearance of MCMV infection

Decreased Diacylglycerol Metabolism Enhances ERK Activation and Augments CD8+ T Cell Functional Responses

The ζ isoform of diacylglycerol kinase plays a predominant role in regulatory T cell development and TCR-mediated ras signaling

The adhesion molecule PECAM-1 enhances the TGF-β-mediated inhibition of T cell function

Signaling in Effector Lymphocytes: Insights toward Safer Immunotherapy

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