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The ecophysiology of leaf cuticular transpiration: are cuticular water permeabilities adapted to ecological conditions?

Journal of experimental botany, 2017-11, Vol.68 (19), p.5271-5279

2017

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Selatogrel, a reversible P2Y12 receptor antagonist, has reduced off-target interference with haemostatic factors in a mouse thrombosis model

Thrombosis research, 2021-04, Vol.200, p.133-140

2021

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Multifunctional Contribution of the Inflated Fruiting Calyx: Implication for Cuticular Barrier Profiles of the Solanaceous Genera Physalis, Alkekengi, and Nicandra

Frontiers in plant science, 2022-07, Vol.13, p.888930-888930

2022

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Protecting against water loss: analysis of the barrier properties of plant cuticles

Journal of experimental botany, 2001-10, Vol.52 (363), p.2023-2032

2001

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P2X1 expressed on polymorphonuclear neutrophils and platelets is required for thrombosis in mice

Blood, 2014-10, Vol.124 (16), p.2575-2585

2014

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Building a Barrier: The Influence of Different Wax Fractions on the Water Transpiration Barrier of Leaf Cuticles

Frontiers in plant science, 2022-01, Vol.12, p.766602-766602

2022

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Insights from In Vitro and Clinical Data to Guide Transition from the Novel P2Y12 Antagonist Selatogrel to Clopidogrel, Prasugrel, and Ticagrelor

Thrombosis and haemostasis, 2021-06, Vol.121 (6), p.755-766

2021

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Distinct phyllosphere bacterial communities on Arabidopsis wax mutant leaves

PloS one, 2013-11, Vol.8 (11), p.e78613-e78613

2013

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The potency of selatogrel, a reversible antagonist of the P2Y12 receptor, is affected by calcium concentration

Platelets (Edinburgh), 2022-01, Vol.33 (1), p.147-156

2022

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4‑((R)‑2-{[6-((S)‑3-Methoxypyrrolidin-1-yl)-2-phenylpyrimidine-4-carbonyl]amino}-3-phosphonopropionyl)piperazine-1-carboxylic Acid Butyl Ester (ACT-246475) and Its Prodrug (ACT-281959), a Novel P2Y12 Receptor Antagonist with a Wider Therapeutic Window in the Rat Than Clopidogrel

Journal of medicinal chemistry, 2015-12, Vol.58 (23), p.9133-9153

2015

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Inverse agonist efficacy of selatogrel blunts constitutive P2Y12 receptor signaling by inducing the inactive receptor conformation

Biochemical pharmacology, 2022-12, Vol.206, p.115291-115291, Article 115291

2022

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Localization of the Transpiration Barrier in the Epi- and Intracuticular Waxes of Eight Plant Species: Water Transport Resistances Are Associated with Fatty Acyl Rather Than Alicyclic Components

Plant physiology (Bethesda), 2016-02, Vol.170 (2), p.921-934

2016

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Selatogrel and Other P2Y12 Inhibitors' Putative Off-Target Effects

Journal of cardiovascular pharmacology, 2022-02, Vol.79 (2), p.153-154

2022

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Identification of 2‑(2-(1-Naphthoyl)-8-fluoro-3,4-dihydro‑1H‑pyrido[4,3‑b]indol-5(2H)‑yl)acetic Acid (Setipiprant/ACT-129968), a Potent, Selective, and Orally Bioavailable Chemoattractant Receptor-Homologous Molecule Expressed on Th2 Cells (CRTH2) Antagonist

Journal of medicinal chemistry, 2013-06, Vol.56 (12), p.4899-4911

2013

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Optimization of 2-phenyl-pyrimidine-4-carboxamides towards potent, orally bioavailable and selective P2Y(12) antagonists for inhibition of platelet aggregation

Bioorganic & medicinal chemistry letters, 2014-09, Vol.24 (17), p.4323-4331

2014

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The P2Y12 Receptor Antagonist Selatogrel Dissolves Preformed Platelet Thrombi In Vivo

Journal of clinical medicine, 2021-11, Vol.10 (22), p.5349

2021

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Abscisic acid mediates the formation of a suberized stem scar tissue in tomato fruits

The New phytologist, 2012-04, Vol.194 (2), p.402-415

2012

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Optogenetic control of plant growth by a microbial rhodopsin

Nature plants, 2021-02, Vol.7 (2), p.144-151

2021

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Water loss from litchi (Litchi chinensis) and longan (Dimocarpus longan) fruits is biphasic and controlled by a complex pericarpal transpiration barrier

Planta, 2015-11, Vol.242 (5), p.1207-1219

2015

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The desert plant Phoenix dactylifera closes stomata via nitrate-regulated SLAC1 anion channel

The New phytologist, 2017-10, Vol.216 (1), p.150-162

2017

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Insights Into Olive Fruit Surface Functions: A Comparison of Cuticular Composition, Water Permeability, and Surface Topography in Nine Cultivars During Maturation

Frontiers in plant science, 2019-11, Vol.10, p.1484-1484

2019

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Revisiting the Functional Basis of Sclerophylly Within the Leaf Economics Spectrum of Oaks: Different Roads to Rome

Current forestry reports, 2020-12, Vol.6 (4), p.260-281

2020

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Phyllosphere bacterial communities of trichome-bearing and trichomeless Arabidopsis thaliana leaves

Antonie van Leeuwenhoek, 2012-03, Vol.101 (3), p.551-560

2012

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Novel 2-(2-(benzylthio)-1H-benzo[d]imidazol-1-yl)acetic acids: Discovery and hit-to-lead evolution of a selective CRTh2 receptor antagonist chemotype

Bioorganic & medicinal chemistry letters, 2012-07, Vol.22 (14), p.4660-4664

2012

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The reversible P2Y12 antagonist ACT‐246475 causes significantly less blood loss than ticagrelor at equivalent antithrombotic efficacy in rat

Pharmacology research & perspectives, 2017-10, Vol.5 (5), p.n/a

2017

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The ecophysiology of leaf cuticular transpiration: are cuticular water permeabilities adapted to ecological conditions?

Selatogrel, a reversible P2Y12 receptor antagonist, has reduced off-target interference with haemostatic factors in a mouse thrombosis model

Multifunctional Contribution of the Inflated Fruiting Calyx: Implication for Cuticular Barrier Profiles of the Solanaceous Genera Physalis, Alkekengi, and Nicandra

Protecting against water loss: analysis of the barrier properties of plant cuticles

P2X1 expressed on polymorphonuclear neutrophils and platelets is required for thrombosis in mice

Building a Barrier: The Influence of Different Wax Fractions on the Water Transpiration Barrier of Leaf Cuticles

Insights from In Vitro and Clinical Data to Guide Transition from the Novel P2Y12 Antagonist Selatogrel to Clopidogrel, Prasugrel, and Ticagrelor

Distinct phyllosphere bacterial communities on Arabidopsis wax mutant leaves

The potency of selatogrel, a reversible antagonist of the P2Y12 receptor, is affected by calcium concentration

4‑((R)‑2-{[6-((S)‑3-Methoxypyrrolidin-1-yl)-2-phenylpyrimidine-4-carbonyl]amino}-3-phosphonopropionyl)piperazine-1-carboxylic Acid Butyl Ester (ACT-246475) and Its Prodrug (ACT-281959), a Novel P2Y12 Receptor Antagonist with a Wider Therapeutic Window in the Rat Than Clopidogrel

Inverse agonist efficacy of selatogrel blunts constitutive P2Y12 receptor signaling by inducing the inactive receptor conformation

Localization of the Transpiration Barrier in the Epi- and Intracuticular Waxes of Eight Plant Species: Water Transport Resistances Are Associated with Fatty Acyl Rather Than Alicyclic Components

Selatogrel and Other P2Y12 Inhibitors' Putative Off-Target Effects

Identification of 2‑(2-(1-Naphthoyl)-8-fluoro-3,4-dihydro‑1H‑pyrido[4,3‑b]indol-5(2H)‑yl)acetic Acid (Setipiprant/ACT-129968), a Potent, Selective, and Orally Bioavailable Chemoattractant Receptor-Homologous Molecule Expressed on Th2 Cells (CRTH2) Antagonist

Optimization of 2-phenyl-pyrimidine-4-carboxamides towards potent, orally bioavailable and selective P2Y(12) antagonists for inhibition of platelet aggregation

The P2Y12 Receptor Antagonist Selatogrel Dissolves Preformed Platelet Thrombi In Vivo

Abscisic acid mediates the formation of a suberized stem scar tissue in tomato fruits

Optogenetic control of plant growth by a microbial rhodopsin

Water loss from litchi (Litchi chinensis) and longan (Dimocarpus longan) fruits is biphasic and controlled by a complex pericarpal transpiration barrier

The desert plant Phoenix dactylifera closes stomata via nitrate-regulated SLAC1 anion channel

Insights Into Olive Fruit Surface Functions: A Comparison of Cuticular Composition, Water Permeability, and Surface Topography in Nine Cultivars During Maturation

Revisiting the Functional Basis of Sclerophylly Within the Leaf Economics Spectrum of Oaks: Different Roads to Rome

Phyllosphere bacterial communities of trichome-bearing and trichomeless Arabidopsis thaliana leaves

Novel 2-(2-(benzylthio)-1H-benzo[d]imidazol-1-yl)acetic acids: Discovery and hit-to-lead evolution of a selective CRTh2 receptor antagonist chemotype

The reversible P2Y12 antagonist ACT‐246475 causes significantly less blood loss than ticagrelor at equivalent antithrombotic efficacy in rat

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